SCHEMBL29586208

SCHEMBL29586208

CC(C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)CF

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 12/20 0.46
BACE2 Q9Y5Z0 3/20 0.46
CTSD P07339 2/20 0.45
ENPEP Q07075 5/20 0.43
CASP3 P42574 2/20 0.41
CASP8 Q14790 2/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2564476 0.89 BACE1 (0.45) BACE1BACE2CTSDENPEPCASP3
SCHEMBL31468688 0.88 BACE1 (0.46) BACE1BACE2CTSDENPEPCASP3
SCHEMBL29576249 0.88 GNPAT (0.44) BACE1BACE2ENPEPCASP3CASP8
SCHEMBL31089740 0.88 ENPEP (0.55) BACE1BACE2CTSDENPEP
SCHEMBL5194261 0.88 ENPEP (0.55) BACE1BACE2CTSDENPEP
SCHEMBL19794 0.87 BACE1 (0.52) BACE1BACE2CTSDENPEP
SCHEMBL4274620 0.85 BACE1 (0.46) BACE1BACE2CTSDENPEPCASP3
SCHEMBL31315589 0.85 BACE1 (0.47) BACE1BACE2CTSDENPEP
SCHEMBL29904046 0.85 BACE1 (0.51) BACE1BACE2CTSDENPEP
SCHEMBL1674822 0.84 BACE1 (0.47) BACE1BACE2CTSDENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053744-A1 NANODELIVERY SYSTEMS FOR EXTENDED RELEASE OF ANTIBODIES UNIV MARYLAND (US) 2026-02-26 US disclosed
EP-4658299-A1 SWITCH RECEPTOR FOR USE IN ADOPTIVE CELL THERAPY Oslo Universitetssykehus HF (NO) 2025-12-10 EP disclosed
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 US disclosed
US-20250011886-A1 Systems and Methods for Targeting COVID-19 Therapies AMPEL BIOSOLUTIONS, LLC 2025-01-09 US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 US disclosed
US-20240287574-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2024-08-29 US disclosed
WO-2024160976-A1 SWITCH RECEPTOR FOR USE IN ADOPTIVE CELL THERAPY OSLO UNIVERSITETSSYKEHUS HF (NO) 2024-08-08 WO disclosed
US-12023335-B2 Method for treating pancreatic cancer PTC THERAPEUTICS, INC. (US) 2024-07-02 US disclosed
US-20230018930-A1 BIOLOGIC PRESERVING COMPOSITION AND METHODS OF USE AESTHETICS BIOMEDICAL, INC. 2023-01-19 US disclosed
US-20230011398-A1 COMBINATION THERAPY APPROACH TO ELIMINATE HIV INFECTIONS THE METHODIST HOSPITAL SYSTEM 2023-01-12 US disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 US disclosed
US-20220354811-A1 METHODS AND COMPOSITIONS FOR MODULATING MACROPHAGES POLARIZATION INST NAT SANTE RECH MED (FR) 2022-11-10 US disclosed
US-11446330-B2 Biologic preserving composition and methods of use AESTHETICS BIOMEDICAL, INC. (US) 2022-09-20 US disclosed
US-20220251158-A1 INTERMEDIATE FILAMENT-DERIVED PEPTIDES AND THEIR USES FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA (ES) 2022-08-11 US disclosed
EP-4037714-A1 METHODS AND COMPOSITIONS FOR MODULATING MACROPHAGES POLARIZATION INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-08-10 EP disclosed
EP-3990002-A1 INTERMEDIATE FILAMENT-DERIVED PEPTIDES AND THEIR USES Universitat de Lleida (ES) 2022-05-04 EP disclosed
US-11299526-B2 p53-BAD fusion proteins UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2022-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 BACE1 2824/4885BACE2 1807/4885CTSD 189/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 BACE1 2824/4885BACE2 1807/4885CTSD 189/4885
US-20220354811-A1 METHODS AND COMPOSITIONS FOR MODULATING MACROPHAGES POLARIZATION CASP4, CASP8, CD14 BACE1 451/4885BACE2 242/4885CTSD 218/4885
US-20260053744-A1 NANODELIVERY SYSTEMS FOR EXTENDED RELEASE OF ANTIBODIES NPC1L1, APOL1, ABCB4 BACE1 128/4885BACE2 170/4885CTSD 1821/4885
US-12023335-B2 Method for treating pancreatic cancer TUBB1, TUBB, TUBB3 BACE1 3617/4885BACE2 2745/4885CTSD 1446/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 BACE1 2824/4885BACE2 1807/4885CTSD 189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.