SCHEMBL29640693

SCHEMBL29640693

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NTSR1 P30989 16/20 0.55
NTSR2 O95665 12/20 0.55
SORT1 Q99523 7/20 0.52
F2 P00734 1/20 0.48
OPRD1 P41143 2/20 0.47
OPRM1 P35372 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30602837 0.96 NTSR1 (0.55) NTSR1NTSR2SORT1F2OPRD1
SCHEMBL30545296 0.95 NTSR1 (0.53) NTSR1NTSR2SORT1F2OPRD1
SCHEMBL31401995 0.91 NTSR1 (0.56) NTSR1NTSR2SORT1F2OPRM1
SCHEMBL29748654 0.88 NTSR1 (0.50) NTSR1NTSR2SORT1F2OPRD1
SCHEMBL29801725 0.87 NTSR2 (0.57) NTSR1NTSR2OPRD1OPRM1
SCHEMBL29904128 0.87 APLNR (0.51) NTSR1NTSR2SORT1F2OPRD1
SCHEMBL29904044 0.86 OPRM1 (0.55) OPRM1
SCHEMBL38655507 0.86 OPRM1 (0.55) OPRM1
SCHEMBL30917327 0.84 NTSR1 (0.54) NTSR1NTSR2SORT1F2
SCHEMBL29679546 0.84 OPRD1 (0.60) F2OPRD1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3529614-B1 METHODS FOR IDENTIFYING A NON-HEALING SKIN WOUND AND FOR MONITORING THE HEALING OF A SKIN WOUND AKRIBES BIOMEDICAL GMBH (AT) 2026-05-06 EP disclosed
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists BAYER AKTIENGESELLSCHAFT (DE) 2025-08-26 US disclosed
CN-119119189-A Polypeptides having MMP2 inhibitory effect 大正制药株式会社 2024-12-13 CN disclosed
CN-114450294-B Polypeptides having MMP2 inhibitory effect 大正制药株式会社 2024-11-26 CN disclosed
US-20240199692-A1 POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT TAISHO PHARMACEUTICAL CO., LTD. (JP) 2024-06-20 US disclosed
EP-4058448-B1 HYDANTOIN DERIVATIVES AS ADAMTS7 ANTAGONISTS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES BAYER AG (DE) 2024-05-29 EP disclosed
US-11579141-B2 Methods for identifying a non-healing skin wound and for monitoring the healing of a skin wound AKRIBES BIOMEDICAL GMBH (AT) 2023-02-14 US disclosed
US-20230027346-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS BAYER AKTIENGESELLSCHAFT (DE) 2023-01-26 US disclosed
US-20230027985-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS BAYER AKTIENGESELLSCHAFT (DE) 2023-01-26 US disclosed
US-20220412975-A1 CHARACTERIZING MODULATORS OF ADAMTS-7 AND ADAMTS-12 BAYER AKTIENGESELLSCHAFT (DE) 2022-12-29 US disclosed
WO-2022265150-A1 EXOSOME-RICH CULTURE MEDIUM OF IMMORTALIZED STEM CELLS AND FUNCTIONAL COMPOSITION COMPRISING BOTULINUM TOXIN 충북대학교 산학협력단 2022-12-22 WO disclosed
EP-4104842-A1 FUNCTIONAL COMPOSITION COMPRISING EXOSOME-RICH CONDITIONED MEDIUM OF IMMORTALIZED STEM CELLS AND BOTULINUM TOXIN Chungbuk National University Industry-Academic Cooperation Foundation (KR) 2022-12-21 EP disclosed
CN-115486537-A Exosome-rich culture media comprising immortalized stem cells and functional compositions of botulinum toxin 忠北大学校产学协力团 2022-12-20 CN disclosed
WO-2022234867-A1 SULFONAMIDE HAVING MMP 7-INHIBITING ACTION 大正製薬株式会社 2022-11-10 WO disclosed
EP-4056581-A1 POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT Taisho Pharmaceutical Co., Ltd. (JP) 2022-09-14 EP disclosed
CN-114878550-A Multifunctional health monitoring contact lens and preparation and detection method thereof 温州医科大学 2022-08-09 CN disclosed
CN-109844529-B Method for identifying non-healing skin wounds and for monitoring skin wound healing 阿克里斯生物医药有限公司 2022-08-02 CN disclosed
CN-114450294-A Polypeptide with MMP2 inhibitory effect 大正制药株式会社 2022-05-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199692-A1 POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT MMP2, MMP26, MMP25 NTSR1 441/4885NTSR2 333/4885SORT1 452/4885
US-20230027985-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS ADAMTS7, MMP7, ADAMTS1 NTSR1 1584/4885NTSR2 1794/4885SORT1 3559/4885
US-12398120-B2 Substituted hydantoinamides as ADAMTS7 antagonists ADAMTS7, MMP7, ADAM17 NTSR1 682/4885NTSR2 1040/4885SORT1 3441/4885
US-20230027346-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS ADAMTS7, MMP7, ADAM17 NTSR1 682/4885NTSR2 1040/4885SORT1 3441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.