Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Picloram. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Picloram SCHEMBL1888813 | 1.00 | TDP1 (0.66) | TDP1LMNAGAAMAPTATM | |
| Potassium Ion SCHEMBL8986486 | 0.81 | TDP1 (0.43) | TDP1LMNAGAAMAPTATM | |
| Picloram SCHEMBL29388079 | 0.79 | TDP1 (1.00) | TDP1LMNAGAAMAPTATM | |
| Picloram SCHEMBL8467014 | 0.79 | TDP1 (1.00) | TDP1LMNAGAAMAPTATM | |
| Picloram SCHEMBL13299 | 0.79 | TDP1 (1.00) | TDP1LMNAGAAMAPTATM | |
| SCHEMBL11616592 | 0.79 | TDP1 (0.70) | TDP1LMNAGAAMAPTATM | |
| SCHEMBL1614180 | 0.78 | TDP1 (0.63) | TDP1LMNAGAAMAPTATM | |
| SCHEMBL29512558 | 0.78 | TDP1 (0.63) | TDP1LMNAGAAMAPTATM | |
| Picloram SCHEMBL7112378 | 0.78 | TDP1 (0.96) | TDP1LMNAGAAMAPTATM | |
| Picloram SCHEMBL5086801 | 0.78 | TDP1 (0.96) | TDP1LMNAGAAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172857-A1 | THE USE OF AN AMINOPYRALID-PICLORAM-TRICLOPYR COMPOSITION TO CONTROL UNWANTED VEGETATION IN SUGARCANE | CORTEVA AGRISCIENCE LLC (US) | 2023-09-14 | — | — | WO | claimed |
| CN-115843801-A | Water dispersible granule containing propanil, 2,4-D potassium salt and picloram potassium salt and preparation method and application thereof | 山东潍坊润丰化工股份有限公司 | 2023-03-28 | — | — | CN | claimed |
| US-20260020563-A1 | METHOD FOR CONTROLLING PESTS OF FARM CROPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2026-01-22 | — | — | US | disclosed |
| EP-4680598-A1 | 4-DIFLUOROMETHYL BENZAMIDES WITH HERBICIDAL ACTION | Bayer Aktiengesellschaft (DE) | 2026-01-21 | — | — | EP | disclosed |
| US-12458023-B2 | Method for controlling pests of farm crops | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-11-04 | — | — | US | disclosed |
| US-20250270581-A1 | METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE | MONSANTO TECHNOLOGY LLC (US) | 2025-08-28 | — | — | US | disclosed |
| US-20250228243-A1 | METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE | MONSANTO TECHNOLOGY LLC (US) | 2025-07-17 | — | — | US | disclosed |
| WO-2025103931-A1 | SUBSTITUTED CYCLOPROPYLOXYPHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2025-05-22 | — | — | WO | disclosed |
| WO-2025103939-A1 | SULFONIMIDOYL BENZAMIDES WITH HERBICIDAL ACTION | BAYER AKTIENGESELLSCHAFT (DE) | 2025-05-22 | — | — | WO | disclosed |
| CN-119546187-A | Method for controlling undesired plants and promoting growth of useful plants | 石原产业株式会社 | 2025-02-28 | — | — | CN | disclosed |
| CN-119423076-A | Aminopyralid triethanolamine salt aqueous auxiliary agent and preparation method thereof | 南京科翼新材料有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-115843801-A | Water dispersible granule containing propanil, 2,4-D potassium salt and picloram potassium salt and preparation method and application thereof | 山东潍坊润丰化工股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115843801-A | Water dispersible granule containing propanil, 2,4-D potassium salt and picloram potassium salt and preparation method and application thereof | 山东潍坊润丰化工股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113873887-B | Herbicidal composition | 石原产业株式会社 | 2023-03-14 | — | — | CN | disclosed |
| CN-115581235-A | Weeding composition and application thereof | 允发化工（上海）有限公司 | 2023-01-10 | — | — | CN | disclosed |
| US-20220272977-A1 | METHOD FOR CONTROLLING PESTS OF FARM CROPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-09-01 | — | — | US | disclosed |
| CN-107426979-B | Plants with increased herbicide tolerance | 巴斯夫欧洲公司 | 2022-07-01 | — | — | CN | disclosed |
| US-11369112-B2 | Method for controlling pests of farm crops | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-06-28 | — | — | US | disclosed |
| WO-2022122825-A1 | DECOLONIZATION OF ENTEROBACTERIA, SUCH AS KLEBSIELLA PNEUMONIAE, FROM THE GUT USING STRAINS OF KLEBSIELLA OXYTOCA | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2022-06-16 | — | — | WO | disclosed |
| EP-4011384-A1 | DECOLONIZATION OF ENTEROBACTERIA, SUCH AS KLEBSIELLA PNEUMONIAE, FROM THE GUT USING STRAINS OF KLEBSIELLA OXYTOCA | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2022-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12458023-B2 | Method for controlling pests of farm crops | THOP1, PNPO, TDO2 | TDP1 713/4885LMNA 4236/4885GAA 3624/4885 |
| US-20260020563-A1 | METHOD FOR CONTROLLING PESTS OF FARM CROPS | DDT, THOP1, TPH1 | TDP1 399/4885LMNA 2565/4885GAA 3707/4885 |
| US-20250270581-A1 | METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE | PPOX, PTPRG, PAOX | TDP1 572/4885LMNA 4495/4885GAA 888/4885 |
| US-20250228243-A1 | METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE | UNG, PNPO, PPOX | TDP1 174/4885LMNA 4459/4885GAA 1000/4885 |
| US-20220272977-A1 | METHOD FOR CONTROLLING PESTS OF FARM CROPS | THOP1, DDT, TPH1 | TDP1 752/4885LMNA 4416/4885GAA 3367/4885 |
| US-11369112-B2 | Method for controlling pests of farm crops | DDT, CYP4X1, PAOX | TDP1 2691/4885LMNA 4455/4885GAA 2365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.