SCHEMBL29670758

SCHEMBL29670758

CC(C)c1ccc2c(c1)Cc1ccccc1S2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.50
OPRK1 P41145 1/20 0.50
PDE4D Q08499 1/20 0.50
ALDH1A1 P00352 3/20 0.42
HPGD P15428 3/20 0.42
KDM4E B2RXH2 2/20 0.42
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
ATM Q13315 1/20 0.42
MAPT P10636 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
NOX1 Q9Y5S8 1/20 0.40
BLM P54132 1/20 0.39
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
CYP17A1 P05093 1/20 0.35
KIF11 P52732 1/20 0.34
DRD2 P14416 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170423 1.00 PTGS2 (0.50) PTGS2OPRK1PDE4DALDH1A1HPGD
SCHEMBL28373276 0.98 PTGS2 (0.49) PTGS2OPRK1PDE4DALDH1A1HPGD
SCHEMBL11824904 0.83 PTGS2 (0.48) PTGS2OPRK1PDE4DALDH1A1HPGD
SCHEMBL2739332 0.82 PTGS2 (0.74) PTGS2OPRK1PDE4DALDH1A1HPGD
SCHEMBL11821456 0.82 PTGS2 (0.74) PTGS2OPRK1PDE4DALDH1A1HPGD
SCHEMBL4734664 0.81 CYP17A1 (0.39) PTGS2OPRK1PDE4DHPGDKMT2A
SCHEMBL1345773 0.78 MEN1 (0.38) PTGS2OPRK1PDE4DALDH1A1HPGD
SCHEMBL31195717 0.77 NOX1 (0.46) PTGS2OPRK1PDE4DALDH1A1HPGD
SCHEMBL11824485 0.77 PTGS2 (0.43) PTGS2OPRK1PDE4DALDH1A1HPGD
SCHEMBL3850258 0.77 ALDH1A1 (0.53) PTGS2OPRK1PDE4DALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595370-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-04-07 US disclosed
EP-4155354-B1 INK COMPOSITION FOR PHOTOCURABLE INKJET PRINTING SAKATA INX CORP (JP) 2026-03-11 EP disclosed
US-20260044018-A1 MULTIFOCAL CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES JOHNSON & JOHNSON VISION CARE (US) 2026-02-12 US disclosed
US-12534623-B2 Contact lens with improved tear film optical quality JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-01-27 US disclosed
US-12515470-B2 UV-Vis radiation curable security inks SICPA HOLDING SA (CH) 2026-01-06 US disclosed
US-20260003209-A1 TORIC CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES JOHNSON & JOHNSON VISION CARE (US) 2026-01-01 US disclosed
US-12503618-B2 Photocurable inkjet printing ink composition SAKATA INX CORPORATION (JP) 2025-12-23 US disclosed
US-12486348-B2 Contact lens displaying improved vision attributes JOHNSON & JOHNSON VISION CARE, INC. (US) 2025-12-02 US disclosed
US-12481173-B2 Multifocal contact lens displaying improved vision attributes JOHNSON & JOHNSON VISION CARE, INC. (US) 2025-11-25 US disclosed
WO-2023233896-A1 PHOTOSENSITIVE RESIN COMPOSITION 東京応化工業株式会社 2023-12-07 WO disclosed
WO-2023233895-A1 POLYIMIDE RESIN PRECURSOR 東京応化工業株式会社 2023-12-07 WO disclosed
WO-2023176172-A1 POLYIMIDE RESIN PRECURSOR 東京応化工業株式会社 2023-09-21 WO disclosed
US-20230220225-A1 PHOTOCURABLE INKJET PRINTING INK COMPOSITION SAKATA INX CORPORATION (JP) 2023-07-13 US disclosed
WO-2023058385-A1 BLOCK COPOLYMER 東京応化工業株式会社 2023-04-13 WO disclosed
EP-4155354-A1 INK COMPOSITION FOR PHOTOCURABLE INKJET PRINTING Sakata INX Corporation (JP) 2023-03-29 EP disclosed
US-20230066936-A1 CONTACT LENS WITH IMPROVED TEAR FILM OPTICAL QUALITY JOHNSON & JOHNSON VISION CARE, INC. 2023-03-02 US disclosed
US-11543683-B2 Multifocal contact lens displaying improved vision attributes JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-01-03 US disclosed
US-20220340760-A1 POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE, INC. 2022-10-27 US disclosed
WO-2022138012-A1 POLYMERIZABLE COMPOSITION AND MANUFACTURING METHOD FOR ELEMENT-MOUNTED SUBSTRATE 東京応化工業株式会社 2022-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595370-B2 Polymerizable absorbers of UV and high energy visible light NLRP3, NLRP1, XDH PTGS2 739/4885OPRK1 765/4885PDE4D 2155/4885
US-20260044018-A1 MULTIFOCAL CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES NECTIN4, CRYAB, PSEN1 PTGS2 2809/4885OPRK1 3558/4885PDE4D 3043/4885
US-20260003209-A1 TORIC CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES TRPA1, LATS2, TEC PTGS2 2313/4885OPRK1 3448/4885PDE4D 2717/4885
US-12534623-B2 Contact lens with improved tear film optical quality CUTA, CRYAA, TCOF1 PTGS2 645/4885OPRK1 3056/4885PDE4D 3003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.