Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482552 | 0.87 | ALDH1A1 (0.78) | ALDH1A1THRBHIF1ACYP3A4ALOX15 | |
| SCHEMBL29390387 | 0.87 | MAPK1 (0.77) | ALDH1A1THRBHIF1ACYP3A4ALOX15 | |
| SCHEMBL18084213 | 0.85 | ALDH1A1 (0.60) | ALDH1A1THRBHIF1ACYP3A4ALOX15 | |
| SCHEMBL18101484 | 0.78 | CYP2C9 (0.61) | ALDH1A1THRBHIF1ACYP3A4ALOX15 | |
| SCHEMBL29438532 | 0.78 | APP (0.66) | ALDH1A1THRBHIF1ACYP3A4ALOX15 | |
| Orange G SCHEMBL28776597 | 0.76 | APP (0.68) | ALDH1A1THRBHIF1ACYP3A4ALOX15 | |
| SCHEMBL29366607 | 0.74 | THRB (1.00) | ALDH1A1THRBHIF1ACYP3A4ALOX15 | |
| SCHEMBL14613548 | 0.67 | ALDH1A1 (0.68) | ALDH1A1THRBHIF1ACYP3A4ALOX15 | |
| SCHEMBL29637844 | 0.67 | PTPN1 (0.81) | ALDH1A1THRBHIF1ACYP3A4ALOX15 | |
| Trypan Blue Free Acid SCHEMBL31686853 | 0.65 | PTPN1 (1.00) | ALDH1A1THRBHIF1ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604790-A | Laminate, optical article, lens, and glasses | 株式会社德山 | 2025-03-11 | — | — | CN | disclosed |
| CN-119072504-A | Curable composition, cured product, laminate, optical article, lens, and glasses | 株式会社德山 | 2024-12-03 | — | — | CN | disclosed |
| US-20240209254-A1 | OPTICAL ARTICLE, SPECTACLE LENS AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2024-06-27 | — | — | US | disclosed |
| US-20240100810-A1 | RESIN COMPOSITION, OPTICAL LAMINATE, OPTICAL ARTICLE, LENS AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2024-03-28 | — | — | US | disclosed |
| EP-4328636-A1 | OPTICAL ARTICLE, SPECTACLE LENS AND SPECTACLES | Tokuyama Corporation (JP) | 2024-02-28 | — | — | EP | disclosed |
| WO-2024018902-A1 | LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES | 株式会社トクヤマ | 2024-01-25 | — | — | WO | disclosed |
| CN-117178209-A | Optical article, spectacle lens and spectacles | 株式会社德山 | 2023-12-05 | — | — | CN | disclosed |
| EP-4282932-A1 | RESIN COMPOSITION, OPTICAL LAMINATE, OPTICAL ARTICLE, LENS, AND GLASSES | Tokuyama Corporation (JP) | 2023-11-29 | — | — | EP | disclosed |
| WO-2023210448-A1 | CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENS, AND SPECTACLES | 株式会社トクヤマ | 2023-11-02 | — | — | WO | disclosed |
| WO-2023210447-A1 | METHOD FOR MANUFACTURING OPTICAL LAYERED SHEET AND METHOD FOR MANUFACTURING OPTICAL ARTICLE | 株式会社トクヤマ | 2023-11-02 | — | — | WO | disclosed |
| CN-116868095-A | Resin composition, optical laminate, optical article, lens, and glasses | 株式会社德山 | 2023-10-10 | — | — | CN | disclosed |
| WO-2023085051-A1 | OPTICAL LAMINATED SHEET, OPTICAL ARTICLE, LENS, SPECTACLES, AND METHOD FOR MANUFACTURING OPTICAL LAMINATED SHEET | 株式会社トクヤマ | 2023-05-19 | — | — | WO | disclosed |
| CN-115768746-A | Compound for optical material, curable composition, cured product, and optical article | 株式会社德山 | 2023-03-07 | — | — | CN | disclosed |
| WO-2022224771-A1 | OPTICAL ARTICLE, SPECTACLE LENS AND SPECTACLES | 株式会社トクヤマ | 2022-10-27 | — | — | WO | disclosed |
| CN-111727402-B | Functional laminate and functional lens using same | 株式会社德山 | 2022-07-15 | — | — | CN | disclosed |