Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.77 |
| ▸ | P2RY4 known ✓ | P51582 | 1/20 | 0.37 |
| ▸ | P2RY6 known ✓ | Q15077 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438532 | 0.91 | APP (0.66) | MAPK1THRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL18084213 | 0.88 | ALDH1A1 (0.60) | MAPK1THRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL29678237 | 0.87 | ALDH1A1 (0.59) | MAPK1THRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL29366607 | 0.87 | THRB (1.00) | MAPK1THRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL18101484 | 0.81 | CYP2C9 (0.61) | MAPK1THRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL29637843 | 0.79 | THRB (0.85) | MAPK1THRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL29568770 | 0.78 | THRB (0.86) | MAPK1THRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL185277 | 0.76 | APP (0.98) | MAPK1THRBALDH1A1TDP1CYP3A4 | |
| Orange G SCHEMBL81967 | 0.75 | APP (1.00) | MAPK1THRBALDH1A1TDP1CYP3A4 | |
| Orange G SCHEMBL29369740 | 0.75 | APP (1.00) | MAPK1THRBALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552745-B2 | Compound for optical materials, curable composition, cured body, and optical article | TOKUYAMA CORPORATION (JP) | 2026-02-17 | — | — | US | disclosed |
| US-20260042309-A1 | THERMAL-TRANSFER RECORDING MEDIUM, TRANSFERRED-MEDIUM FILM, AND METHOD FOR PRODUCING TRANSFERRED-MEDIUM FILM | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2026-02-12 | — | — | US | disclosed |
| US-20250355282-A1 | LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2025-11-20 | — | — | US | disclosed |
| WO-2025233535-A1 | METHOD FOR THE DETERMINATION OF CLEAVAGE SITES IN GENOMIC DNA CAUSED BY EXPOSURE TO A SITE DIRECTED NUCLEASE | ETH Zürich (CH) | 2025-11-13 | — | — | WO | disclosed |
| US-20250257162-A1 | CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-08-14 | — | — | US | disclosed |
| US-12383504-B2 | Acid resistant banding solution for two piece hard capsules | CAPSUGEL BELGIUM NV (BE) | 2025-08-12 | — | — | US | disclosed |
| US-12359081-B2 | Ink, method for producing ink, and inkjet system | RICOH COMPANY, LTD. (JP) | 2025-07-15 | — | — | US | disclosed |
| EP-4566830-A1 | FILM TO WHICH TRANSFER HAS BEEN COMPLETED AND PRODUCTION METHOD FOR FILM TO WHICH TRANSFER HAS BEEN COMPLETED | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2025-06-11 | — | — | EP | disclosed |
| EP-4566829-A1 | THERMAL TRANSFER RECORDING MEDIUM, TRANSFER-COMPLETED FILM, AND PRODUCTION METHOD FOR TRANSFER-COMPLETED FILM | General Co., Ltd. (JP) | 2025-06-11 | — | — | EP | disclosed |
| EP-4566831-A1 | THERMAL-TRANSFER RECORDING MEDIUM, TRANSFERRED-MEDIUM FILM, AND METHOD FOR PRODUCING TRANSFERRED-MEDIUM FILM | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2025-06-11 | — | — | EP | disclosed |
| CN-110337454-B | Water-soluble composition, method for producing cured product thereof, and acylphosphinate | 株式会社ADEKA | 2022-04-12 | — | — | CN | disclosed |
| WO-2022072401-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | UNIVERSITY OF MIAMI (US) | 2022-04-07 | — | — | WO | disclosed |
| CN-109765652-B | Composite retardation plate, optical laminate, and image display device | 住友化学株式会社 | 2022-03-25 | — | — | CN | disclosed |
| CN-114185124-A | Laminate and image display device | 住友化学株式会社 | 2022-03-15 | — | — | CN | disclosed |
| CN-114174874-A | Laminated body | 住友化学株式会社 | 2022-03-11 | — | — | CN | disclosed |
| WO-2022050003-A1 | OPTICAL LAMINATE, AND ELLIPSOIDALLY POLARIZING PLATE INCLUDING SAME | 住友化学株式会社 | 2022-03-10 | — | — | WO | disclosed |
| CN-107664788-B | Optical laminate | 住友化学株式会社 | 2022-03-04 | — | — | CN | disclosed |
| CN-114144709-A | Polarizing film and method for producing same | 住友化学株式会社 | 2022-03-04 | — | — | CN | disclosed |
| CN-114127590-A | Optical laminate and method for producing same | 住友化学株式会社 | 2022-03-01 | — | — | CN | disclosed |
| CN-114072708-A | Optical laminate | 住友化学株式会社 | 2022-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552745-B2 | Compound for optical materials, curable composition, cured body, and optical article | C5, SCO2, ZYX | THRB 2158/4885P2RY4 1739/4885P2RY6 1602/4885 |
| US-20260042309-A1 | THERMAL-TRANSFER RECORDING MEDIUM, TRANSFERRED-MEDIUM FILM, AND METHOD FOR PRODUCING TRANSFERRED-MEDIUM FILM | TRRAP, TRMT1L, TES | THRB 1259/4885P2RY4 1715/4885P2RY6 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.