Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613650 | 0.80 | NPSR1 (0.82) | NPSR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24445725 | 0.80 | NPSR1 (0.82) | NPSR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11034598 | 0.70 | CYP3A4 (0.60) | NPSR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4654049 | 0.68 | TDP1 (0.72) | NPSR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19712968 | 0.65 | TDP1 (0.62) | NPSR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27424267 | 0.65 | LMNA (0.52) | NPSR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9049960 | 0.63 | MAPT (0.64) | NPSR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6937543 | 0.63 | DDX3X (0.50) | NPSR1L3MBTL1TDP1MAPTALDH1A1 | |
| SCHEMBL28896841 | 0.62 | TDP1 (1.00) | NPSR1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25387353 | 0.62 | L3MBTL1 (0.54) | NPSR1CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220313633-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220313633-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES | HPGDS, ARG1, RELA | NPSR1 1811/4885CYP3A4 3831/4885CYP2D6 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.