Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037406 | 0.84 | FOLH1 (0.42) | ECE1MMESIRT2SIRT1FOLH1 | |
| SCHEMBL3046493 | 0.84 | FOLH1 (0.42) | ECE1MMESIRT2SIRT1FOLH1 | |
| SCHEMBL3054282 | 0.83 | MME (0.43) | ECE1MMESIRT2SIRT1FOLH1 | |
| SCHEMBL3042749 | 0.82 | FOLH1 (0.42) | ECE1MMESIRT2SIRT1FOLH1 | |
| SCHEMBL5689331 | 0.82 | FOLH1 (0.33) | SIRT2FOLH1 | |
| SCHEMBL3046195 | 0.81 | CTSL (0.35) | ECE1MMEFOLH1CTSL | |
| SCHEMBL3053901 | 0.81 | FOLH1 (0.40) | ECE1MMEFOLH1 | |
| SCHEMBL3050998 | 0.80 | ECE1 (0.43) | ECE1MMESIRT2SIRT1FOLH1 | |
| SCHEMBL3049456 | 0.80 | FOLH1 (0.39) | ECE1MMESIRT2SIRT1FOLH1 | |
| Trifluoroacetic Acid SCHEMBL3044628 | 0.79 | MME (0.42) | ECE1MMESIRT2SIRT1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265537-B1 | CYCLIC COMPOUNDS; NEMATOCIDES FOR HUMANS AND ANIMALS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-24 | — | — | US | claimed |
| CN-110475776-B | Tricyclic carboxamides for combating arthropods | 拜耳作物科学股份公司 | 2024-03-19 | — | — | CN | disclosed |
| EP-4298908-A2 | TRICYCLIC CARBOXAMIDES FOR THE CONTROL OF ARTHROPODS | Bayer Animal Health GmbH (DE) | 2024-01-03 | — | — | EP | disclosed |
| US-11825838-B2 | Tricyclic carboxamides for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2023-11-28 | — | — | US | disclosed |
| EP-3601279-B1 | TRICYCLIC CARBOXAMIDES AS CONTROL AGENT FOR ARTHROPODS | BAYER ANIMAL HEALTH GMBH (DE) | 2023-10-18 | — | — | EP | disclosed |
| US-20210106005-A1 | TRICYCLIC CARBOXAMIDES FOR CONTROLLING ARTHROPODS | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-04-15 | — | — | US | disclosed |
| US-10836732-B2 | Compounds for combating arthropods | BAYER ANIMAL HEALTH GMBH (DE) | 2020-11-17 | — | — | US | disclosed |
| EP-3601279-A1 | TRICYCLIC CARBOXAMIDES FOR CONTROLLING ARTHROPODS | Bayer CropScience Aktiengesellschaft (DE) | 2020-02-05 | — | — | EP | disclosed |
| US-10357036-B2 | Compounds for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-23 | — | — | US | disclosed |
| US-10273226-B2 | Pyrazolyl-heteroarylamides as pesticides | BAYER ANIMAL HEALTH GMBH (DE) | 2019-04-30 | — | — | US | disclosed |
| US-20050080272-A1 | Halogenated nitrobutadienes for controlling animal pests | BAYER CROPSCIENCE AG (DE) | 2005-04-14 | — | — | US | disclosed |
| US-20050043333-A1 | Quinazolinone derivative | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20040077667-A1 | Quinazolinone derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-04-22 | — | — | US | disclosed |
| US-20040034048-A1 | Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
| US-20020142969-A1 | DIDEPSIPEPTIDE-BASED ENDOPARASITICIDES, NEW DIDEPSIPEPTIDES AND PROCESS FOR PREPARING THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | US | disclosed |
| US-6306872-B1 | TREATMENT OF ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-23 | — | — | US | disclosed |
| US-6291472-B1 | 4a, 5a, 8a, 8b-tetrahydro-6H-pyrrolo[3′,4′:4, 5]furo[3,2-b] pyri-dine-6,8(7H)-dione derivatives for control of endoparasites processes for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-18 | — | — | US | disclosed |
| US-6265537-B1 | CYCLIC COMPOUNDS; NEMATOCIDES FOR HUMANS AND ANIMALS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-24 | — | — | US | disclosed |
| US-6110928-A | HUMAN OR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-29 | — | — | US | disclosed |
| US-6033879-A | Process for the preparation of substituted aryl lactic acid containing cyclodepsipeptides with 24 ring atoms | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11825838-B2 | Tricyclic carboxamides for controlling arthropods | AADAC, FAAH, FAAH2 | ECE1 579/4885MME 159/4885SIRT2 148/4885 |
| US-20040034048-A1 | Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same | VIP, NGLY1, NPEPPS | ECE1 195/4885MME 90/4885SIRT2 4061/4885 |
| US-20210106005-A1 | TRICYCLIC CARBOXAMIDES FOR CONTROLLING ARTHROPODS | AADAC, FAAH, FAAH2 | ECE1 579/4885MME 159/4885SIRT2 148/4885 |
| US-20050080272-A1 | Halogenated nitrobutadienes for controlling animal pests | HDHD5, OTUB1, CBR3 | ECE1 4077/4885MME 1343/4885SIRT2 891/4885 |
| US-20050043333-A1 | Quinazolinone derivative | PARP1, PARP11, PARP2 | ECE1 2134/4885MME 3687/4885SIRT2 277/4885 |
| US-10357036-B2 | Compounds for controlling arthropods | DDT, ACHE, NISCH | ECE1 647/4885MME 183/4885SIRT2 1460/4885 |
| US-20020142969-A1 | DIDEPSIPEPTIDE-BASED ENDOPARASITICIDES, NEW DIDEPSIPEPTIDES AND PROCESS FOR PREPARING THE SAME | VIP, NGLY1, NPEPPS | ECE1 171/4885MME 91/4885SIRT2 4130/4885 |
| US-10836732-B2 | Compounds for combating arthropods | PRDX4, SERPINB6, GSTA1 | ECE1 396/4885MME 1068/4885SIRT2 2352/4885 |
| US-20040077667-A1 | Quinazolinone derivatives | PARP1, PARP9, PARP2 | ECE1 890/4885MME 3424/4885SIRT2 730/4885 |
| US-10273226-B2 | Pyrazolyl-heteroarylamides as pesticides | CYP4Z1, NAT1, CYP4F3 | ECE1 1009/4885MME 1764/4885SIRT2 1507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.