Pramiconazole

Pramiconazole

SCHEMBL3048310

CC(C)N1CCN(c2ccc(N3CCN(c4ccc(OC[C@H]5OC[C@](Cn6cncn6)(c6ccc(F)cc6F)O5)cc4)CC3)cc2)C1=O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 16/20 0.55
▸ ABCG2 Q9UNQ0 4/20 0.55
▸ CYP17A1 P05093 4/20 0.55
▸ CYP19A1 P11511 4/20 0.55
▸ CYP11B1 P15538 4/20 0.55
▸ ABCB11 O95342 3/20 0.55
▸ CYP8B1 Q9UNU6 3/20 0.55
▸ CYP2C9 P11712 2/20 0.55
▸ CYP11B2 P19099 2/20 0.55
▸ PTGS2 P35354 1/20 0.55
▸ LMNA P02545 3/20 0.44
▸ CYP51A1 Q16850 3/20 0.44
▸ FYN P06241 2/20 0.44
▸ NR1I2 O75469 2/20 0.44
▸ HSP90AA1 P07900 2/20 0.44
▸ CHRM2 P08172 2/20 0.44
▸ ADRA2A P08913 2/20 0.44
▸ TSHR P16473 2/20 0.44
▸ ADRA2B P18089 2/20 0.44
▸ SLC6A2 P23975 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pramiconazole SCHEMBL3048307 1.00 CYP3A4 (0.55) CYP3A4ABCG2CYP17A1CYP19A1CYP11B1
Pramiconazole SCHEMBL6152243 0.99 CYP3A4 (0.55) CYP3A4ABCG2CYP17A1CYP19A1CYP11B1
Pramiconazole SCHEMBL6152244 0.99 CYP3A4 (0.55) CYP3A4ABCG2CYP17A1CYP19A1CYP11B1
SCHEMBL6151936 0.94 CYP3A4 (0.56) CYP3A4ABCG2CYP17A1CYP19A1CYP11B1
SCHEMBL6151935 0.94 CYP3A4 (0.56) CYP3A4ABCG2CYP17A1CYP19A1CYP11B1
SCHEMBL17832624 0.90 CYP3A4 (0.43) CYP3A4ABCG2CYP17A1CYP19A1CYP11B1
SCHEMBL17824324 0.90 CYP3A4 (0.43) CYP3A4ABCG2CYP17A1CYP19A1CYP11B1
SCHEMBL19730470 0.90 CYP3A4 (0.43) CYP3A4ABCG2CYP17A1CYP19A1CYP11B1
SCHEMBL29726392 0.90 CYP3A4 (0.51) CYP3A4ABCG2CYP17A1CYP19A1CYP11B1
SCHEMBL9254879 0.90 CYP3A4 (0.54) CYP3A4ABCG2CYP17A1CYP19A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220260565-A1 METHODS OF TREATING AND DIAGNOSING INFLAMMATORY BOWEL DISEASE CEDARS-SINAI MEDICAL CENTER (US) 2022-08-18 — — US claimed
WO-2001001955-A1 NASAL FORMULATION OF AN ANTIFUNGAL JANSSEN PHARMACEUTICA N.V. (BE) 2001-01-11 — — WO claimed
US-20260083668-A1 ORALLY ADMINISTERED CORTICOSTEROID COMPOSITIONS ELLODI PHARMACEUTICALS L P (US) 2026-03-26 — — US disclosed
US-20260083754-A1 CORTICOSTEROID CONTAINING ORALLY DISINTEGRATING TABLET COMPOSITIONS FOR EOSINOPHILIC ESOPHAGITIS ELLODI PHARMACEUTICALS, L.P. 2026-03-26 — — US disclosed
US-12540358-B2 RNASET2 compositions and methods of treatment therewith CEDARS-SINAI MEDICAL CENTER (US) 2026-02-03 — — US disclosed
US-20260027129-A1 CORTICOSTEROID CONTAINING ORALLY DISINTEGRATING TABLET COMPOSITIONS FOR EOSINOPHILIC ESOPHAGITIS ELLODI PHARMACEUTICALS L P (US) 2026-01-29 — — US disclosed
US-20260021041-A1 ORALLY ADMINISTERED CORTICOSTEROID COMPOSITIONS ELLODI PHARMACEUTICALS L P (US) 2026-01-22 — — US disclosed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 — — EP disclosed
US-20250340627-A1 METHODS OF SELECTING, BASED ON POLYMORPHISMS, AN INFLAMMATORY BOWEL DISEASE SUBJECT FOR TREATMENT WITH AN ANTI-TL1A ANTIBODY PROMETHEUS BIOSCIENCES INC (US) 2025-11-06 — — US disclosed
US-12447157-B2 Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis ELLODI PHARMACEUTICALS, L.P. (US) 2025-10-21 — — US disclosed
US-12391752-B2 Methods of enriching or amplifying nucleic acids in a sample from a patient with inflammatory bowel disease PROMETHEUS BIOSCIENCES, INC. (US) 2025-08-19 — — US disclosed
US-20100222588-A1 Method for Manufacture of 2-Oxoimidazolidines THESIS CHEMISTRY, LLC (US) 2010-09-02 — — US disclosed
US-20100222588-A1 Method for Manufacture of 2-Oxoimidazolidines THESIS CHEMISTRY, LLC (US) 2010-09-02 — — US disclosed
WO-2009114080-A2 PROCESSES FOR PREPARING ENANTIOMERICALLY PURE DIOL AND DIOXOLANE COMPOUNDS STIEFEL LABORATORIES, INC. (US) 2009-09-17 — — WO disclosed
US-20060078609-A1 Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water soluble and respectively base JANSSEN PHARMACEUTICA N.V. (BE) 2006-04-13 — — US disclosed
EP-1068200-B1 2,4,4-TRISUBSTITUTED-1,3-DIOXOLANE ANTIFUNGALS JANSSEN PHARMACEUTICA NV (BE) 2005-02-16 — — EP disclosed
WO-2004050068-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A BASIC RESPECTIVELY ACIDIC DRUG COMPOUND, A SURFACTANT AND A PHYSIOLOGICALLY TOLERABLE WATER-SOLUBLE ACID RESPECTIVELY BASE JANSSEN PHARMACEUTICA N.V. (BE) 2004-06-17 — — WO disclosed
EP-0998304-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING A BASIC DRUG, A CYCLODEXTRIN, A POLYMER AND AN ACID JANSSEN PHARMACEUTICA NV (BE) 2003-08-20 — — EP disclosed
US-20020150616-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CYCLODEXTRINS JANSSEN PHARMACEUTICA N.V. (BE) 2002-10-17 — — US disclosed
US-6387906-B1 DERMATOPHYTES JANSSEN PHARMACEUTICA N.V. (BE) 2002-05-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540358-B2 RNASET2 compositions and methods of treatment therewith RNASE1, TRDMT1, RNASEH1 CYP3A4 3874/4885ABCG2 2535/4885CYP17A1 3923/4885
US-20060078609-A1 Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water soluble and respectively base SLC10A1, SLC7A1, SLC26A4 CYP3A4 578/4885ABCG2 13/4885CYP17A1 968/4885
US-20260027129-A1 CORTICOSTEROID CONTAINING ORALLY DISINTEGRATING TABLET COMPOSITIONS FOR EOSINOPHILIC ESOPHAGITIS IL5, CMA1, CTSD CYP3A4 177/4885ABCG2 2826/4885CYP17A1 156/4885
US-20250340627-A1 METHODS OF SELECTING, BASED ON POLYMORPHISMS, AN INFLAMMATORY BOWEL DISEASE SUBJECT FOR TREATMENT WITH AN ANTI-TL1A ANTIBODY TLL1, TSG101, DNASE1L3 CYP3A4 4442/4885ABCG2 2920/4885CYP17A1 3473/4885
US-20260021041-A1 ORALLY ADMINISTERED CORTICOSTEROID COMPOSITIONS IL17A, CYP4A11, USP7 CYP3A4 77/4885ABCG2 2682/4885CYP17A1 11/4885
US-12391752-B2 Methods of enriching or amplifying nucleic acids in a sample from a patient with inflammatory bowel disease DNASE1L3, TLL1, RNASE1 CYP3A4 4806/4885ABCG2 4336/4885CYP17A1 3624/4885
US-20260083754-A1 CORTICOSTEROID CONTAINING ORALLY DISINTEGRATING TABLET COMPOSITIONS FOR EOSINOPHILIC ESOPHAGITIS TSLP, CMA1, SI CYP3A4 836/4885ABCG2 2747/4885CYP17A1 417/4885
US-20100222588-A1 Method for Manufacture of 2-Oxoimidazolidines ODC1, CBR3, CBR1 CYP3A4 35/4885ABCG2 2293/4885CYP17A1 1186/4885
US-20260083668-A1 ORALLY ADMINISTERED CORTICOSTEROID COMPOSITIONS IL17A, MUC1, SI CYP3A4 138/4885ABCG2 2636/4885CYP17A1 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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