Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SI | P14410 | 2/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180145 | 0.88 | CTSK (0.38) | CTSKCA1CA2TSHRALDH1A1 | |
| SCHEMBL10938384 | 0.87 | MAPT (0.39) | CTSKCA1CA2ALDH1A1MMP1 | |
| SCHEMBL8990510 | 0.85 | CTSK (0.33) | CTSKCA1CA2MMP1MMP2 | |
| SCHEMBL1469110 | 0.85 | ACACB (0.40) | CTSKCA1CA2PRKCAPRKCD | |
| SCHEMBL31731146 | 0.84 | CA1 (0.35) | CTSKCA1CA2ALDH1A1MGAM | |
| SCHEMBL5537588 | 0.84 | CA1 (0.35) | CTSKCA1CA2PRKCAPRKCD | |
| Bicarbonate SCHEMBL3240516 | 0.83 | CTSK (0.36) | CTSKCA2ALDH1A1SOAT1PRKCA | |
| SCHEMBL14185384 | 0.83 | SOAT1 (0.43) | CTSKALDH1A1SOAT1PRKCAPRKCD | |
| SCHEMBL1470047 | 0.82 | CA1 (0.34) | CTSKCA1CA2TSHRALDH1A1 | |
| SCHEMBL1440094 | 0.79 | ALDH1A1 (0.57) | CTSKALDH1A1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658639-B2 | N-substituted-cyclic amino derivative | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-02-25 | — | — | US | claimed |
| US-20120122773-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-17 | — | — | US | claimed |
| EP-2447264-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-05-02 | — | — | EP | claimed |
| US-7687490-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2010-03-30 | — | — | US | claimed |
| EP-1870412-A1 | 2-THIOETHENYL CARBAPENEM DERIVATIVE | MEIJI SEIKA KAISHA LTD. (JP) | 2007-12-26 | — | — | EP | claimed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | claimed |
| US-20040176350-A1 | Carbapenem compound | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2004-09-09 | — | — | US | claimed |
| EP-1398314-A1 | CARBAPENEM COMPOUND | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2004-03-17 | — | — | EP | claimed |
| US-20220209301-A1 | CARBONATE SOLVENTS FOR NON-AQUEOUS ELECTROLYTES FOR METAL AND METAL-ION BATTERIES | SCE FRANCE (FR) | 2022-06-30 | — | — | US | disclosed |
| EP-3956288-A1 | CARBONATE SOLVENTS FOR NON-AQUEOUS ELECTROLYTES FOR METAL AND METAL-ION BATTERIES | SCE France (FR) | 2022-02-23 | — | — | EP | disclosed |
| WO-2020212872-A1 | CARBONATE SOLVENTS FOR NON-AQUEOUS ELECTROLYTES FOR METAL AND METAL-ION BATTERIES | SCE FRANCE (FR) | 2020-10-22 | — | — | WO | disclosed |
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | MEIJI SEIKA KAISHA (JP) | 2016-06-02 | — | — | US | disclosed |
| US-9260375-B2 | Metallo-β-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| EP-2415875-B1 | METHOD FOR IDENTIFICATION OF METALLO-[BETA]-LACTAMASE-PRODUCING BACTERIUM | MEIJI SEIKA PHARMA CO LTD (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-20040176350-A1 | Carbapenem compound | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
| EP-1398314-A1 | CARBAPENEM COMPOUND | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-20040014962-A1 | 1-Methylcarbapenem derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-01-22 | — | — | US | disclosed |
| EP-1340757-A1 | 1-METHYLCARBAPENEM DERIVATIVES | Sankyo Company, Limited (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0682023-B1 | Imidazopyridine derivatives and process for preparing the same | TANABE SEIYAKU CO (JP) | 1997-02-12 | — | — | EP | disclosed |
| EP-0682023-A1 | Imidazopyridine derivatives and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014962-A1 | 1-Methylcarbapenem derivatives | CD14, CPT1A, ACMSD | CTSK 3012/4885CA1 2558/4885CA2 2546/4885 |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MTAP, BLVRB, BPGM | CTSK 3219/4885CA1 3160/4885CA2 1641/4885 |
| US-20040176350-A1 | Carbapenem compound | ALPI, SI, OXA1L | CTSK 2122/4885CA1 3950/4885CA2 3197/4885 |
| US-20120122773-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | REN, AGTR1, AGTR2 | CTSK 2053/4885CA1 769/4885CA2 62/4885 |
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | ME1, MGAM, MANBA | CTSK 505/4885CA1 921/4885CA2 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.