Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2B | O00750 | 2/20 | 0.36 |
| ▸ | PIK3C2G | O75747 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 3/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782048 | 0.78 | PGR (0.54) | SCN9APGRCCR9KMT2AALDH1A1 | |
| SCHEMBL4777634 | 0.78 | SLC40A1 (0.47) | SCN9APGRACLYKDM1AMAOA | |
| SCHEMBL4775751 | 0.78 | SLC40A1 (0.44) | PGRACLYKDM1AMAOAMAPT | |
| SCHEMBL4842459 | 0.78 | ALDH1A1 (0.47) | PGRKMT2AALDH1A1PKMMEN1 | |
| SCHEMBL3091275 | 0.77 | — | — | |
| SCHEMBL4781817 | 0.76 | SLC40A1 (0.48) | PIK3C2BPIK3C2GSCN9APGRACLY | |
| SCHEMBL4840971 | 0.69 | ALDH1A1 (0.47) | KMT2AALDH1A1GAAPKMMEN1 | |
| SCHEMBL3089179 | 0.68 | SLC40A1 (0.46) | PGRACLYALDH1A1 | |
| SCHEMBL4781338 | 0.68 | SLC40A1 (0.48) | KMT2AALDH1A1GAAMEN1MAPT | |
| SCHEMBL30304671 | 0.67 | KEAP1 (0.50) | PGRCCR9KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234364-A1 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234364-A1 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CCR2, CCR9, CCR1 | PIK3C2B 3662/4885PIK3C2G 3682/4885SCN9A 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.