Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 7/20 | 0.56 |
| ▸ | CA1 known ✓ | P00915 | 5/20 | 0.50 |
| ▸ | CA12 known ✓ | O43570 | 4/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL30745859 | 0.97 | CA2 (0.54) | CA2PLCG1CA1MMP2CA12 | |
| Potassium Ion SCHEMBL8717887 | 0.94 | CA2 (0.56) | CA2PLCG1CA1MMP2CA12 | |
| SCHEMBL6908356 | 0.94 | CA2 (0.56) | CA2PLCG1CA1MMP2CA12 | |
| SCHEMBL8714151 | 0.94 | CA2 (0.56) | CA2PLCG1CA1MMP2CA12 | |
| SCHEMBL6915964 | 0.94 | CA2 (0.56) | CA2PLCG1CA1MMP2CA12 | |
| SCHEMBL6918764 | 0.94 | CA2 (0.56) | CA2PLCG1CA1MMP2CA12 | |
| Zinc Ion SCHEMBL6915196 | 0.94 | CA2 (0.56) | CA2PLCG1CA1MMP2CA12 | |
| SCHEMBL6914838 | 0.94 | CA2 (0.56) | CA2PLCG1CA1MMP2CA12 | |
| SCHEMBL6914699 | 0.94 | CA2 (0.56) | CA2PLCG1CA1MMP2CA12 | |
| SCHEMBL8714923 | 0.94 | CA2 (0.56) | CA2PLCG1CA1MMP2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118325091-A | Side chain type sulfonated polyarylethersulfone (ketone) and preparation method and application thereof | 吉林化工学院 | 2024-07-12 | — | — | CN | claimed |
| CN-116375907-A | Method for producing sugammadex | 默沙东有限责任公司 | 2023-07-04 | — | — | CN | claimed |
| CN-111777534-B | Alkynyl sulfone compound and preparation method and application thereof | 南京林业大学 | 2022-04-12 | — | — | CN | claimed |
| US-20210206884-A1 | PROCESSES FOR THE PREPARATION OF SUGAMMADEX | MERCK SHARP & DOHME CORP. (US) | 2021-07-08 | — | — | US | claimed |
| EP-3802627-A1 | PROCESSES FOR THE PREPARATION OF SUGAMMADEX | Merck Sharp & Dohme Corp. (US) | 2021-04-14 | — | — | EP | claimed |
| CN-112449642-A | Process for preparing sugammadex | 默沙东公司 | 2021-03-05 | — | — | CN | claimed |
| CN-110526847-B | Synthesis method of N-aryl sulfuryl sulfoxide imine | 成都理工大学 | 2021-01-19 | — | — | CN | claimed |
| CN-108276324-B | Synthesis method of diaryl sulfone compound containing 2-diaryl methyl indole skeleton | 苏州大学 | 2020-04-10 | — | — | CN | claimed |
| US-7008646-B2 | Cubic liquid crystalline compositions and methods for their preparation | CHILDREN'S HOSPITAL RESEARCH FOUNDATION | 2006-03-07 | — | — | US | claimed |
| EP-0897808-B1 | Recording sheets and ink jet printing processes therewith | XEROX CORP (US) | 2004-06-16 | — | — | EP | claimed |
| EP-1361865-A2 | CUBIC LIQUID CRYSTALLINE COMPOSITIONS AND METHODS FOR THEIR PREPARATION | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-19 | — | — | EP | claimed |
| US-20020160040-A1 | Cubic liquid crystalline compositions and methods for their preparation | CHILDREN'S HOSPITAL RESEARCH FOUNDATION | 2002-10-31 | — | — | US | claimed |
| WO-2002066014-A2 | CUBIC LIQUID CRYSTALLINE COMPOSITIONS AND METHODS FOR THEIR PREPARATION | THE PROCTER & GAMBLE COMPANY (US) | 2002-08-29 | — | — | WO | claimed |
| US-6117527-A | RECORDING SHEET COMPRISING SUBSTRATE HAVING IMAGE-RECEIVING COATING ON SURFACE COMPRISING BINDER POLYMER AND SELECTED ADDITIVE; HIGH QUALITY IMAGES WITH REDUCED OR NO HAZE | XEROX CORPORATION (US) | 2000-09-12 | — | — | US | claimed |
| EP-0897808-A1 | Recording sheets and ink jet printing processes therewith | Xerox Corporation (US) | 1999-02-24 | — | — | EP | claimed |
| US-12564546-B2 | Self-tanning compositions containing an aromatic sulfonate and methods thereof | KAO CORPORATION (JP) | 2026-03-03 | — | — | US | disclosed |
| CN-115485240-B | Sun-blocking compositions containing alkyl sulfonates and methods thereof | 花王株式会社 | 2024-12-27 | — | — | CN | disclosed |
| US-5744678-A | NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY | NIPPON OIL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0758563-A1 | OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT | NIPPON OIL COMPANY, LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |
| US-5043510-A | Aqueous alkylation process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160040-A1 | Cubic liquid crystalline compositions and methods for their preparation | SKP1, CCNB1, CRYAA | CA2 364/4885CA1 54/4885CA12 639/4885 |
| US-12564546-B2 | Self-tanning compositions containing an aromatic sulfonate and methods thereof | CUTA, TYR, TREH | CA2 939/4885CA1 3800/4885CA12 666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.