Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649151 | 0.91 | ACHE (0.43) | HSD11B1LTA4HACHE | |
| SCHEMBL31649462 | 0.91 | ACHE (0.43) | HSD11B1LTA4HACHE | |
| SCHEMBL31649221 | 0.89 | HSD11B1 (0.40) | MEN1KMT2AHRH3HSD11B1CPT2 | |
| SCHEMBL31649016 | 0.84 | HRH3 (0.36) | MEN1KMT2AHRH3HSD11B1FAAH | |
| SCHEMBL31649065 | 0.83 | TACR1 (0.39) | MEN1KMT2AHSD11B1CPT2CPT1A | |
| SCHEMBL31649407 | 0.83 | ALDH1A1 (0.41) | RORCMEN1KMT2AHRH3HSD11B1 | |
| SCHEMBL31649185 | 0.83 | ALDH1A1 (0.46) | MEN1KMT2APOLBNPC1 | |
| SCHEMBL31649158 | 0.83 | ALDH1A1 (0.46) | MEN1KMT2APOLBNPC1 | |
| SCHEMBL31649296 | 0.82 | HTR2A (0.40) | RORCMEN1KMT2AHSD11B1POLB | |
| SCHEMBL31649206 | 0.80 | OPRM1 (0.39) | RORCHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |