Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.41 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL23387433 | 0.98 | CA1 (0.39) | CA4CA1CA5ACA5BOR51E2 | |
| SCHEMBL3847418 | 0.98 | CA1 (0.39) | CA4CA1CA5ACA5BOR51E2 | |
| SCHEMBL5467168 | 0.98 | CA1 (0.39) | CA4CA1CA5ACA5BOR51E2 | |
| SCHEMBL1832597 | 0.81 | OR51E2 (0.42) | OR51E2PGK1PGK2 | |
| SCHEMBL121274 | 0.81 | OR51E2 (0.42) | OR51E2PGK1PGK2 | |
| SCHEMBL29273470 | 0.80 | CA1 (0.39) | CA4CA1CA5ACA5B | |
| SCHEMBL5579171 | 0.79 | OR51E2 (0.40) | CA4OR51E2PGK1PGK2 | |
| SCHEMBL17513026 | 0.79 | OR51E2 (0.40) | OR51E2PGK1PGK2 | |
| SCHEMBL6852791 | 0.77 | OR51E2 (0.39) | OR51E2PGK1PGK2 | |
| SCHEMBL29666492 | 0.74 | PGK1 (0.36) | OR51E2PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433218-B1 | COMPOSITION BASED ON CALCIUM OXIDE | SIKA TECH AG (CH) | 2024-05-22 | — | — | EP | claimed |
| US-10793471-B2 | Composition based on calcium oxide | SIKA TECHNOLOGY AG (CH) | 2020-10-06 | — | — | US | claimed |
| US-20190084880-A1 | COMPOSITION BASED ON CALCIUM OXIDE | SIKA TECHNOLOGY AG (CH) | 2019-03-21 | — | — | US | claimed |
| US-20260014101-A1 | PETROLATUM-BASED DELIVERY SYSTEMS AND FOR ACTIVE INGREDIENTS | GLOBAL HEALTH SOLUTIONS LLC (US) | 2026-01-15 | — | — | US | disclosed |
| US-12083221-B2 | Petrolatum-based delivery systems and for active ingredients | GLOBAL HEALTH SOLUTIONS LLC | 2024-09-10 | — | — | US | disclosed |
| US-11964039-B2 | Compositions that brighten skin, provide sun protection, and permit vitamin D production | ARMSTRONG ERNEST T (US) | 2024-04-23 | — | — | US | disclosed |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-20220087917-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2022-03-24 | — | — | US | disclosed |
| US-20220016010-A1 | COMPOSITIONS THAT BRIGHTEN SKIN, PROVIDE SUN PROTECTION, AND PERMIT VITAMIN D PRODUCTION | ARMSTRONG ERNEST T (US) | 2022-01-20 | — | — | US | disclosed |
| US-20210401744-A1 | PETROLATUM-BASED DELIVERY SYSTEMS AND FOR ACTIVE INGREDIENTS | GLOBAL HEALTH SOLUTIONS LLC (US) | 2021-12-30 | — | — | US | disclosed |
| US-11077046-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | BIOSPLICE THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| WO-2017124156-A1 | COMPOSITIONS THAT BRIGHTEN SKIN, PROVIDE SUN PROTECTION, AND PERMIT VITAMIN D PRODUCTION | ARMSTRONG ERNEST T (AU) | 2017-07-27 | — | — | WO | disclosed |
| WO-2016204959-A1 | PETROLATUM-BASED DELIVERY SYSTEMS AND FOR ACTIVE INGREDIENTS | Global Health Solutions, Inc. (US) | 2016-12-22 | — | — | WO | disclosed |
| US-20160367676-A1 | PETROLATUM-BASED DELIVERY SYSTEMS AND FOR ACTIVE INGREDIENTS | GLOBAL HEALTH SOLUTIONS LLC | 2016-12-22 | — | — | US | disclosed |
| US-20160206540-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | VICKERS-SPLICE CO-INVESTMENT LLC (KY) | 2016-07-21 | — | — | US | disclosed |
| WO-2016029021-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | SAMUMED, LLC (US) | 2016-02-25 | — | — | WO | disclosed |
| US-8092592-B2 | Additive for hydraulic binding agent with long processing time and high early strength | SIKA TECHNOLOGY AG (CH) | 2012-01-10 | — | — | US | disclosed |
| US-20110067604-A1 | ADDITIVE FOR HYDRAULIC BINDING AGENT WITH LONG PROCESSING TIME AND HIGH EARLY STRENGTH | SIKA TECHNOLOGY AG (CH) | 2011-03-24 | — | — | US | disclosed |
| US-20050201917-A1 | Partially crystalline mesostructured material consisting of cerium oxide, of zirconium oxide or of titanium oxide and comprising an element in solid solution in said oxide | RHODIA ELECTRONICS AND CATALYSIS (FR) | 2005-09-15 | — | — | US | disclosed |
| EP-0814374-A2 | Stabilized heat-sensitive imaging material | LABELON CORPORATION (US) | 1997-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077046-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | GLA, DGKG, DGKA | CA4 3810/4885CA1 4884/4885CA5A 2671/4885 |
| US-20220087917-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | GLA, DGKG, DGKA | CA4 3810/4885CA1 4884/4885CA5A 2671/4885 |
| US-20260014101-A1 | PETROLATUM-BASED DELIVERY SYSTEMS AND FOR ACTIVE INGREDIENTS | FLNA, CUTA, FLNB | CA4 4219/4885CA1 4837/4885CA5A 3008/4885 |
| US-20160206540-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | GLA, DGKG, DGKA | CA4 3810/4885CA1 4884/4885CA5A 2671/4885 |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | DGKG, DGKA, DNER | CA4 4150/4885CA1 4880/4885CA5A 3808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.