Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 11/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231169 | 0.80 | CYP2A6 (0.45) | CYP2A6CYP3A4ALDH1A1CYP1A2HSP90AA1 | |
| SCHEMBL231750 | 0.79 | ASIC3 (0.45) | CYP2A6CYP3A4ALDH1A1CYP1A2HSP90AA1 | |
| SCHEMBL606773 | 0.78 | LMNA (0.42) | CYP3A4ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3608908 | 0.77 | CYP2A6 (0.32) | CYP2A6 | |
| SCHEMBL296179 | 0.76 | CYP2A6 (0.62) | CYP2A6CYP3A4ALDH1A1CYP1A2CYP2E1 | |
| SCHEMBL1278034 | 0.76 | CYP2A6 (0.56) | CYP2A6CYP3A4ALDH1A1CYP1A2LOXL2 | |
| SCHEMBL9813674 | 0.76 | CYP2A6 (0.32) | CYP2A6 | |
| SCHEMBL4672073 | 0.75 | CYP2A6 (0.67) | CYP2A6CYP3A4ALDH1A1CYP1A2LOXL2 | |
| SCHEMBL31140239 | 0.75 | CYP2A6 (0.67) | CYP2A6CYP3A4ALDH1A1CYP1A2LOXL2 | |
| SCHEMBL8597147 | 0.74 | CYP2A6 (0.50) | CYP2A6CYP3A4ALDH1A1CYP1A2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240465-B1 | NOVEL PHENOL COMPOUNDS AND (CO)POLYMERS THEREOF | SIKKEMA DOETZE JAKOB (NL) | 2015-10-14 | — | — | EP | claimed |
| EP-2411376-B1 | INHIBITORS OF NF-KB | PROFECTUS BIOSCIENCES INC (US) | 2015-04-22 | — | — | EP | claimed |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | US | claimed |
| US-20130039870-A1 | Cosmetic Or Dermatological Preparations With A Content Of One Or More Thiazole Derivates | BEIERSDORF AG (DE) | 2013-02-14 | — | — | US | claimed |
| CN-102741222-A | Haloalkyl-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG | 2012-10-17 | — | — | CN | claimed |
| EP-2493844-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | Bayer CropScience AG (DE) | 2012-09-05 | — | — | EP | claimed |
| US-20120015952-A1 | Inhibitors of NF-KB | PROFECTUS BIOSCIENCES, INC. (US) | 2012-01-19 | — | — | US | claimed |
| US-7943646-B2 | Benzamidine derivative, process for the preparation thereof and pharmaceutical composition comprising same | DONG WHA PHARMACEUTICAL CO., LTD. (KR) | 2011-05-17 | — | — | US | claimed |
| WO-2011054436-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-12 | — | — | WO | claimed |
| US-20110105532-A1 | Haloalkyl-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | claimed |
| EP-1786790-B1 | OXAZOLE DERIVATIVES AS HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | LILLY CO ELI (US) | 2009-06-03 | — | — | EP | claimed |
| EP-0944645-B1 | INHIBITORS OF INTERLEUKIN-1beta CONVERTING ENZYME | VERTEX PHARMA (US) | 2005-03-09 | — | — | EP | claimed |
| US-20020013346-A1 | C7 ester substituted taxanes | FSU RESEARCH FOUNDATION, INC. | 2002-01-31 | — | — | US | claimed |
| US-20240251665-A1 | TRANSVERSE CURRENT SUPPRESSING MATERIAL, CARBAZOLE COMPOUND, HOLE-INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT | TOSOH CORPORATION (JP) | 2024-07-25 | — | — | US | disclosed |
| US-20240122065-A1 | METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN | TOSOH CORPORATION (JP) | 2024-04-11 | — | — | US | disclosed |
| EP-4342883-A1 | PHOTOELECTRIC CONVERSION ELEMENT MATERIAL FOR IMAGING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT | Tosoh Corporation (JP) | 2024-03-27 | — | — | EP | disclosed |
| US-6077952-A | Cephaloporins and homologues | PFIZER INC. (US) | 2000-06-20 | — | — | US | disclosed |
| US-6063956-A | APPLYING FUNGICIDE OR INSECTICIDE TO THE LOCUS WHERE CONTROL IS DESIRED | ROHM AND HAAS COMPANY (US) | 2000-05-16 | — | — | US | disclosed |
| WO-1999028305-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-10 | — | — | WO | disclosed |
| CN-1130378-A | Pyridazinone derivatives or their salts, processes of their production, and anti-shock agents containing them | ISHIHARA SANGYO KAISHA (JP) | 1996-09-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130039870-A1 | Cosmetic Or Dermatological Preparations With A Content Of One Or More Thiazole Derivates | TYR, CUTA, MITF | CYP2A6 942/4885CYP3A4 1481/4885ALDH1A1 95/4885 |
| US-20120015952-A1 | Inhibitors of NF-KB | NFKBIA, IKBKB, IKBKG | CYP2A6 3568/4885CYP3A4 3206/4885ALDH1A1 2365/4885 |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | CRYAA, ACLY, CRYZ | CYP2A6 106/4885CYP3A4 943/4885ALDH1A1 769/4885 |
| US-20240251665-A1 | TRANSVERSE CURRENT SUPPRESSING MATERIAL, CARBAZOLE COMPOUND, HOLE-INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT | AXIN2, FZD7, SLC39A3 | CYP2A6 2185/4885CYP3A4 404/4885ALDH1A1 3265/4885 |
| US-20110105532-A1 | Haloalkyl-substituted amides as insecticides and acaricides | CRYAA, ACLY, CRYZ | CYP2A6 106/4885CYP3A4 943/4885ALDH1A1 769/4885 |
| US-20020013346-A1 | C7 ester substituted taxanes | CCR7, CASP7, UGT2B7 | CYP2A6 633/4885CYP3A4 873/4885ALDH1A1 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.