SCHEMBL3267918

SCHEMBL3267918

O=c1c2ccccc2oc2c(Br)cccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 12/20 0.64
KDM4E B2RXH2 4/20 0.61
ALDH1A1 P00352 3/20 0.61
GLA P06280 1/20 0.61
CYP3A4 P08684 1/20 0.61
MAPT P10636 1/20 0.61
HPGD P15428 1/20 0.61
PGAM1 P18669 1/20 0.61
CASP1 P29466 1/20 0.61
CASP7 P55210 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
HSD17B10 Q99714 1/20 0.61
NPC1 O15118 1/20 0.58
LMNA P02545 1/20 0.58
RAB9A P51151 1/20 0.58
PTGS2 P35354 1/20 0.56
KDM5A P29375 1/20 0.49
EGFR P00533 1/20 0.46
CYP19A1 P11511 1/20 0.46
CYP11B1 P15538 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15678569 0.86 LOXL2 (0.50) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL636238 0.84 ALOX5 (0.46) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL29552175 0.84 ALOX5 (0.46) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL29902443 0.83 GABRP (0.47) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL19642433 0.83 MAOA (0.51) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL28504758 0.83 GABRP (0.47) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL29547886 0.83 MAOA (0.51) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL22337110 0.82 MAOA (0.44) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL12608741 0.81 MAOA (0.68) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL29164297 0.81 MAOA (0.55) MAOAKDM4EALDH1A1GLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11647671-B2 Compound and organic electro-optical device containing the same WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-05-09 US disclosed
US-11647671-B2 Compound and organic electro-optical device containing the same WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-05-09 US disclosed
WO-2022264759-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT キヤノン株式会社 2022-12-22 WO disclosed
CN-111253393-B Long-life triplet exciton confinement material and application thereof in OLED (organic light emitting diode) device 北京大学 2022-01-25 CN disclosed
WO-2021103060-A1 HOLE TRANSPORT MATERIAL, PREPARATION METHOD THEREFOR, AND ORGANIC LIGHT EMITTING DEVICE 武汉华星光电半导体显示技术有限公司 2021-06-03 WO disclosed
WO-2021103060-A1 HOLE TRANSPORT MATERIAL, PREPARATION METHOD THEREFOR, AND ORGANIC LIGHT EMITTING DEVICE 武汉华星光电半导体显示技术有限公司 2021-06-03 WO disclosed
CN-111253393-A Long-life triplet exciton confinement material and application thereof in OLED (organic light emitting diode) device 北京大学 2020-06-09 CN disclosed
CN-111018875-A Hole transport material, preparation method thereof and organic light-emitting device 武汉华星光电半导体显示技术有限公司 2020-04-17 CN disclosed
CN-109337676-B Deep blue photo-thermal activation delayed fluorescence material and application thereof 武汉华星光电半导体显示技术有限公司 2020-04-10 CN disclosed
US-10305040-B2 Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices MERCK PATENT GMBH (DE) 2019-05-28 US disclosed
EP-1896467-A2 TRICYCLIC OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2008-03-12 EP disclosed
WO-2006138528-A2 TRICYCLIC OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V (BE) 2006-12-28 WO disclosed
US-20060287297-A1 TRICYCLIC OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2006-12-21 US disclosed
EP-0005379-B2 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1986-06-04 EP disclosed
US-4552830-A UNSATURATED COMPOUND, FREE RADICAL-PRODUCING PHOTOINITIATOR FLUORA COLOR FORMER, PROTON DONOR DYNACHEM CORPORATION (US) 1985-11-12 US disclosed
US-4544467-A PHOSPHOROUS-CONTAINING UNSATURATED MONOMER , SULFUR COMPOUND AND PHOTOINITIATOR; BONDING STRENGTH MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-01 US disclosed
EP-0132318-A1 Light-curable dentin and enamel adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-01-30 EP disclosed
US-4343885-A PHOTORESISTS DYNACHEM CORPORATION (US) 1982-08-10 US disclosed
EP-0005380-B1 PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER Dynachem Corporation (US) 1982-01-06 EP disclosed
EP-0005379-B1 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1981-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10305040-B2 Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices SORD, ALDH1A1, SDHA MAOA 1434/4885KDM4E 3566/4885ALDH1A1 2/4885
US-20060287297-A1 TRICYCLIC OPIOID MODULATORS OPRD1, OPRM1, OPRK1 MAOA 555/4885KDM4E 2206/4885ALDH1A1 927/4885
US-11647671-B2 Compound and organic electro-optical device containing the same EPCAM, LPO, CYBA MAOA 205/4885KDM4E 507/4885ALDH1A1 1369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.