Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519386 | 0.85 | ALDH1A1 (0.38) | CNR1EGFRDRD2DRD4DRD3 | |
| SCHEMBL14128387 | 0.81 | CNR1 (0.33) | CNR1EGFR | |
| SCHEMBL28009978 | 0.79 | — | — | |
| SCHEMBL7172295 | 0.75 | MAOA (0.42) | MAOADRD2DRD4DRD3 | |
| SCHEMBL28400893 | 0.73 | ALDH1A1 (0.51) | CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL1680340 | 0.72 | — | — | |
| SCHEMBL7003873 | 0.71 | GPR84 (0.41) | MAOADRD2DRD4DRD3 | |
| SCHEMBL79201 | 0.70 | MAOA (0.47) | MAOADRD2DRD4DRD3 | |
| SCHEMBL25422764 | 0.69 | — | — | |
| SCHEMBL8955030 | 0.69 | GPR84 (0.44) | MAOADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101486673-B | Optical activity 2-(2-nitro-ethyl)-pyrrole, synthetic method and use | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2011-12-07 | — | — | CN | claimed |
| CN-101486673-A | Optical activity 2-(2-nitro-ethyl)-pyrrole, synthetic method and use | SHANGHAI INST ORGANIC CHEM (CN) | 2009-07-22 | — | — | CN | claimed |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2021-02-16 | — | — | US | disclosed |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | UNITED STATES DEPARTMENT OF ENERGY | 2019-10-10 | — | — | US | disclosed |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | UNITED STATES DEPARTMENT OF ENERGY | 2019-08-22 | — | — | US | disclosed |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-04-09 | — | — | US | disclosed |
| WO-2018102252-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-06-07 | — | — | WO | disclosed |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | UNIV NORTH CAROLINA STATE (US) | 2018-03-15 | — | — | US | disclosed |
| WO-2018035281-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-02-22 | — | — | WO | disclosed |
| US-9822123-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2017-11-21 | — | — | US | disclosed |
| WO-2007064841-A2 | PORPHYRINIC COMPOUNDS FOR USE IN FLOW CYTOMETRY | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007064842-A2 | SYNTHESIS OF CHLORINS AND PHORBINES WITH ENHANCED RED SPECTRAL FEATURES | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007047925-A2 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-31 | — | — | US | disclosed |
| WO-2006089122-A2 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-08-24 | — | — | WO | disclosed |
| US-20040152887-A1 | Regioisomerically pure oxochlorins and methods of synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-08-05 | — | — | US | disclosed |
| US-6765092-B2 | OXIDIZING A CHLORIN TO PRODUCE A MIXTURE OF HYDROXYCHLORIN AND OXOCHLORIN, AND THEN OXIDIZING THE HYDROXYCHLORIN, PREFERABLY WITH DDQ | NORTH CAROLINA STATE UNIVERSITY | 2004-07-20 | — | — | US | disclosed |
| WO-2003050082-A2 | REGIOISOMERICALLY PURE OXOCHLORINS AND METHODS OF SYNTHESIS | NORTH CAROLINA STATE UNIVERSITY (US) | 2003-06-19 | — | — | WO | disclosed |
| US-20020137925-A1 | Regioisomerically pure oxochlorins and methods of synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253033-B2 | De novo synthesis of bacteriochlorins | BCL6, ALDH1A2, ALAD | CNR1 2672/4885EGFR 4196/4885MAOA 2447/4885 |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | PCNA, SCD, BCL6 | CNR1 3085/4885EGFR 3371/4885MAOA 4137/4885 |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | DLD, HCCS, PPIF | CNR1 4076/4885EGFR 2981/4885MAOA 3061/4885 |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | PPOX, MRPL19, PYCR1 | CNR1 2844/4885EGFR 1322/4885MAOA 3421/4885 |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | DLD, HCCS, PPIF | CNR1 4076/4885EGFR 2981/4885MAOA 3061/4885 |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | PPOX, PPIC, ALAD | CNR1 3193/4885EGFR 2849/4885MAOA 3520/4885 |
| US-20040152887-A1 | Regioisomerically pure oxochlorins and methods of synthesis | DDT, AOC1, DNMT1 | CNR1 2466/4885EGFR 3276/4885MAOA 1872/4885 |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | CNR1 2672/4885EGFR 4196/4885MAOA 2447/4885 |
| US-20020137925-A1 | Regioisomerically pure oxochlorins and methods of synthesis | DDT, AOC1, DNMT1 | CNR1 2412/4885EGFR 3009/4885MAOA 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.