Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18643837 | 0.91 | HDAC7 (0.56) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL18664295 | 0.90 | HDAC7 (0.54) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL18664332 | 0.90 | HDAC7 (0.54) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL3921437 | 0.89 | HDAC8 (0.54) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL27627008 | 0.85 | HDAC7 (0.50) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL25090841 | 0.85 | CA2 (0.57) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL25634041 | 0.84 | MMP2 (0.54) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL13500244 | 0.84 | HDAC7 (0.48) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL14275111 | 0.84 | HDAC8 (0.48) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL20987781 | 0.81 | MMP3 (0.55) | HDAC8HDAC6HDAC1HDAC2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096802-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-05-22 | — | — | US | claimed |
| EP-0632008-B1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1998-02-04 | — | — | EP | claimed |
| EP-0632008-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-04 | — | — | EP | claimed |
| US-20230202977-A1 | CYCLIC LIPIDS AND METHODS OF USE THEREOF | RENAGADE THERAPEUTICS MANAGEMENT INC. | 2023-06-29 | — | — | US | disclosed |
| EP-3344611-B1 | SPINOSYN DERIVATIVES AS INSECTICIDES | AGRIMETIS LLC (US) | 2020-11-04 | — | — | EP | disclosed |
| US-10717756-B2 | Spinosyn derivatives as insecticides | AGRIMETIS, LLC (US) | 2020-07-21 | — | — | US | disclosed |
| US-20190071464-A1 | SPINOSYN DERIVATIVES AS INSECTICIDES | AGRIMETIS, LLC (US) | 2019-03-07 | — | — | US | disclosed |
| EP-3344611-A1 | SPINOSYN DERIVATIVES AS INSECTICIDES | Agrimetis, LLC (US) | 2018-07-11 | — | — | EP | disclosed |
| EP-2846794-B1 | BICYCLIC SULFONE COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE | MERCK SHARP & DOHME (US) | 2017-11-01 | — | — | EP | disclosed |
| WO-2017040769-A1 | SPINOSYN DERIVATIVES AS INSECTICIDES | AGRIMETIS, LLC (US) | 2017-03-09 | — | — | WO | disclosed |
| US-8569058-B2 | Nerve regeneration promoters | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| EP-1615925-B1 | IMIDAZOPYRIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS | IPSEN PHARMA (FR) | 2009-05-27 | — | — | EP | disclosed |
| US-20080139651-A1 | COMPOUNDS USEFUL FOR TREATING NEUROLOGICAL DISORDERS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2008-06-12 | — | — | US | disclosed |
| US-20080081839-A1 | COMPOUNDS USEFUL FOR TREATING NEUROLOGICAL DISORDERS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2008-04-03 | — | — | US | disclosed |
| US-20070043114-A1 | Nerve regeneration promoters | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| US-7176240-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-7176240-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| WO-2006090169-A1 | 2,4-DIAMINO-PYRIDOPYRIMIDINE DERIVATIVES AND THEIR USE AS MTOR INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2006-08-31 | — | — | WO | disclosed |
| EP-1685832-A1 | NERVE REGENERATION PROMOTERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-20060004098-A1 | Compounds useful for treating neurological disorders | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043114-A1 | Nerve regeneration promoters | BDNF, NGF, GAP43 | HDAC7 1014/4885HDAC8 2501/4885HDAC6 3144/4885 |
| US-20030096802-A1 | Pentanoic acid derivatives | FFAR3, FPR1, FPR3 | HDAC7 1310/4885HDAC8 2107/4885HDAC6 1457/4885 |
| US-10717756-B2 | Spinosyn derivatives as insecticides | ACHE, NISCH, SPIN3 | HDAC7 3924/4885HDAC8 3714/4885HDAC6 4076/4885 |
| US-20060004098-A1 | Compounds useful for treating neurological disorders | GAP43, CLN6, NLN | HDAC7 1185/4885HDAC8 1166/4885HDAC6 126/4885 |
| US-20230202977-A1 | CYCLIC LIPIDS AND METHODS OF USE THEREOF | SGMS1, SGMS2, LNPEP | HDAC7 2435/4885HDAC8 2425/4885HDAC6 3287/4885 |
| US-20080139651-A1 | COMPOUNDS USEFUL FOR TREATING NEUROLOGICAL DISORDERS | GAP43, CLN6, NLN | HDAC7 1185/4885HDAC8 1166/4885HDAC6 126/4885 |
| US-20190071464-A1 | SPINOSYN DERIVATIVES AS INSECTICIDES | ACHE, NISCH, SPIN3 | HDAC7 3924/4885HDAC8 3714/4885HDAC6 4076/4885 |
| US-20080081839-A1 | COMPOUNDS USEFUL FOR TREATING NEUROLOGICAL DISORDERS | GAP43, CLN6, NLN | HDAC7 1185/4885HDAC8 1166/4885HDAC6 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.