Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 known ✓ | Q9H244 | 7/20 | 0.35 |
| ▸ | P2RY2 known ✓ | P41231 | 4/20 | 0.35 |
| ▸ | P2RY4 known ✓ | P51582 | 3/20 | 0.35 |
| ▸ | P2RY6 known ✓ | Q15077 | 3/20 | 0.35 |
| ▸ | P2RY1 known ✓ | P47900 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340440 | 0.92 | APP (0.41) | ALDH1A1HTTP2RY12P2RY2P2RY4 | |
| SCHEMBL340899 | 0.84 | THRB (0.34) | ALDH1A1P2RY12GAAKMT2AMEN1 | |
| SCHEMBL31679136 | 0.84 | THRB (0.34) | ALDH1A1P2RY12GAAKMT2AMEN1 | |
| SCHEMBL15115318 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HTTCDK2DEPTORGFER | |
| SCHEMBL2865909 | 0.82 | HTT (0.39) | ALDH1A1HTTP2RY12P2RY2P2RY4 | |
| SCHEMBL340828 | 0.74 | EIF2AK2 (0.35) | ALDH1A1P2RY12GAALMNAMAPT | |
| SCHEMBL21055662 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HTTP2RY12P2RY2P2RY4 | |
| SCHEMBL342135 | 0.74 | MAPT (0.35) | ALDH1A1HTTP2RY12P2RY2P2RY4 | |
| SCHEMBL15113039 | 0.73 | TTR (0.40) | ALDH1A1HTTP2RY4CDK2DEPTOR | |
| SCHEMBL21436655 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HTTP2RY12DEPTORPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743523-B1 | Dye-based reference material, preparation and use thereof | BAYER AG (US) | 2002-08-28 | — | — | EP | claimed |
| US-20260043720-A1 | STABILIZED TWO-PART HEMATOXYLIN SOLUTION UTILIZING pH ADJUSTMENT | VENTANA MED SYST INC (US) | 2026-02-12 | — | — | US | disclosed |
| US-20250377301-A1 | STABILISED FLUOROPHORES, COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | FREISTAAT BAYERN LUDWIG MAXIMILIANS UNIV MUENCHEN (DE) | 2025-12-11 | — | — | US | disclosed |
| US-12474240-B2 | Stabilized two-part hematoxylin solution utilizing pH adjustment | VENTANA MEDICAL SYSTEMS, INC. (US) | 2025-11-18 | — | — | US | disclosed |
| CN-118841644-A | Application of dye molecule as additive in preparation of electrolyte | 中山大学 | 2024-10-25 | — | — | CN | disclosed |
| US-20230097824-A1 | SEMI-SYNTHESIS AND USE OF RACEMIC HEMATOXYLIN | ROCHE DIAGNOSTICS GMBH (DE) | 2023-03-30 | — | — | US | disclosed |
| EP-4147024-A2 | SEMI-SYNTHESIS AND USE OF RACEMIC HEMATOXYLIN | Ventana Medical Systems, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |
| CN-115552214-A | Semi-synthesis and use of racemic hematoxylin | 文塔纳医疗系统公司 | 2022-12-30 | — | — | CN | disclosed |
| WO-2022188373-A1 | METHOD FOR DETECTING WATER-SOLUBLE ANIONIC SYNTHETIC PIGMENT IN FOOD | 广州市食品检验所（广州市酒类检测中心） | 2022-09-15 | — | — | WO | disclosed |
| EP-3622266-B1 | STABILIZED TWO-PART HEMATOXYLIN SOLUTION UTILIZING PH ADJUSTMENT, METHOD FOR STAINING AND KIT | VENTANA MED SYST INC (US) | 2022-08-17 | — | — | EP | disclosed |
| US-7713472-B2 | Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-05-11 | — | — | US | disclosed |
| US-7651661-B2 | Medical devices with broad spectrum antimicrobial activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-01-26 | — | — | US | disclosed |
| EP-2092385-A1 | ILLUMINATION SOURCE COMPRISING LIGHT EMITTING DIODES FOR STAINED BIOLOGICAL SAMPLES | Cytyc Corporation (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7561329-B2 | Illumination source for stained biological samples | CYTYC CORPORATION (US) | 2009-07-14 | — | — | US | disclosed |
| US-20080183152-A1 | MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY | RAAD ISSAM | 2008-07-31 | — | — | US | disclosed |
| WO-2008073728-A1 | ILLUMINATION SOURCE COMPRISING LIGHT EMITTING DIODES FOR STAINED BIOLOGICAL SAMPLES | CYTYC CORPORATION (US) | 2008-06-19 | — | — | WO | disclosed |
| US-20080144169-A1 | ILLUMINATION SOURCE FOR STAINED BIOLOGICAL SAMPLES | CYTYC CORPORATION (US) | 2008-06-19 | — | — | US | disclosed |
| US-20070154621-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2007-07-05 | — | — | US | disclosed |
| US-20050197634-A1 | Methods for coating and impregnating medical devices with antiseptic compositions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2005-09-08 | — | — | US | disclosed |
| US-4550016-A | STAINED SPECIMEN HAVING CONTRAST AND COLORATION; RAPID DIAGNOSIS | HARRIS CYNTHIA J | 1985-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250377301-A1 | STABILISED FLUOROPHORES, COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | CRY1, MKI67, IK | P2RY12 2136/4885P2RY2 2822/4885P2RY4 2925/4885 |
| US-20260043720-A1 | STABILIZED TWO-PART HEMATOXYLIN SOLUTION UTILIZING pH ADJUSTMENT | SMCHD1, KIT, CD68 | P2RY12 2144/4885P2RY2 3036/4885P2RY4 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.