Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 known ✓ | P41231 | 1/20 | 0.31 |
| ▸ | P2RY4 known ✓ | P51582 | 1/20 | 0.31 |
| ▸ | P2RY6 known ✓ | Q15077 | 1/20 | 0.31 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | P2RY13 | Q9BPV8 | 1/20 | 0.31 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865909 | 0.91 | HTT (0.39) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL340828 | 0.89 | EIF2AK2 (0.35) | MAPTALDH1A1L3MBTL1P2RY12 | |
| SCHEMBL21055662 | 0.79 | ALDH1A1 (0.41) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL22031597 | 0.78 | MEN1 (0.39) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30100332 | 0.77 | MEN1 (0.38) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2864397 | 0.77 | MEN1 (0.38) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL21436238 | 0.76 | ALDH1A1 (0.41) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL21436655 | 0.76 | ALDH1A1 (0.41) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5344218 | 0.76 | MEN1 (0.37) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5344213 | 0.76 | MEN1 (0.37) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710996-B1 | Sunscreen compositions comprising colour pigments | BASF SE (DE) | 2022-08-17 | — | — | EP | disclosed |
| US-11384033-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | BASF SE (DE) | 2022-07-12 | — | — | US | disclosed |
| CN-107108388-B | Composition comprising (thio) phosphoric triamide and other compounds such as amines and colorants with improved urease-inhibiting effect | 巴斯夫欧洲公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112374933-A | Composition comprising (thio) phosphoric triamide and other compounds such as amines and colorants with improved urease-inhibiting effect | 巴斯夫欧洲公司 | 2021-02-19 | — | — | CN | disclosed |
| EP-3763692-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO) PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | BASF SE (DE) | 2021-01-13 | — | — | EP | disclosed |
| EP-3763691-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO)PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | BASF SE (DE) | 2021-01-13 | — | — | EP | disclosed |
| EP-3725756-A2 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING AMINES, OR COLORANTS, AND AN ADDUCT OF THE THREE COMPOUNDS N-(N-BUTYL) THIOPHOSPHORIC ACID TRIAMIDE (NBPT), UREA, AND FORMALDEHYDE | BASF SE (DE) | 2020-10-21 | — | — | EP | disclosed |
| US-20200157018-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO)PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | BASF SE (DE) | 2020-05-21 | — | — | US | disclosed |
| US-10577290-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | BASF SE (DE) | 2020-03-03 | — | — | US | disclosed |
| EP-3459520-A1 | HAIR DYEING COMPOSITION | BASF SE (DE) | 2019-03-27 | — | — | EP | disclosed |
| US-20170369385-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO)PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | BASF SE (DE) | 2017-12-28 | — | — | US | disclosed |
| EP-3237360-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO) PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | BASF SE (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-20170231889-A1 | Sunscreen Compositions Comprising Colour Pigments | BASF SE (DE) | 2017-08-17 | — | — | US | disclosed |
| WO-2016103168-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO) PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | BASF SE (DE) | 2016-06-30 | — | — | WO | disclosed |
| EP-2710996-A2 | Sunscreen compositions comprising colour pigments | BASF SE (DE) | 2014-03-26 | — | — | EP | disclosed |
| US-8268014-B2 | Hair dyeing composition | BASF SE Ludwigshafen (DE) | 2012-09-18 | — | — | US | disclosed |
| US-8257448-B2 | Hair dyeing composition | BASF SE (DE) | 2012-09-04 | — | — | US | disclosed |
| US-20120017931-A1 | HAIR DYEING COMPOSITION | BASF SE (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20120012128-A1 | HAIR DYEING COMPOSITION | BASF SE (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20110033400-A1 | SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS | BASF SE (US) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120012128-A1 | HAIR DYEING COMPOSITION | CYC1, CYB5R3, TYR | P2RY2 3991/4885P2RY4 3823/4885P2RY6 4397/4885 |
| US-20200157018-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO)PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | SLC14A1, XDH, PNP | P2RY2 539/4885P2RY4 1162/4885P2RY6 408/4885 |
| US-20110033400-A1 | SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS | TYR, ERCC1, ERCC4 | P2RY2 2981/4885P2RY4 3656/4885P2RY6 3926/4885 |
| US-20120017931-A1 | HAIR DYEING COMPOSITION | CYB5R3, CYC1, CYCS | P2RY2 3460/4885P2RY4 3539/4885P2RY6 4063/4885 |
| US-11384033-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | SLC14A1, XDH, PNP | P2RY2 539/4885P2RY4 1162/4885P2RY6 408/4885 |
| US-20170231889-A1 | Sunscreen Compositions Comprising Colour Pigments | TYR, ERCC1, ERCC4 | P2RY2 2981/4885P2RY4 3656/4885P2RY6 3926/4885 |
| US-20170369385-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO)PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | SLC14A1, XDH, PNP | P2RY2 539/4885P2RY4 1162/4885P2RY6 408/4885 |
| US-10577290-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | SLC14A1, XDH, PNP | P2RY2 539/4885P2RY4 1162/4885P2RY6 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.