Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 11/20 | 0.39 |
| ▸ | CNR1 | P21554 | 8/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isosulfan Blue Inner Salt SCHEMBL3324345 | 0.90 | MEN1 (0.44) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL341270 | 0.89 | THRB (0.45) | MEN1KMT2AALDH1A1MAPTCNR2 | |
| SCHEMBL126069 | 0.81 | THRB (0.47) | MEN1KMT2AALDH1A1MAPTBLM | |
| SCHEMBL124487 | 0.80 | THRB (0.50) | MEN1KMT2AALDH1A1MAPTBLM | |
| SCHEMBL340120 | 0.80 | MEN1 (0.40) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL20740546 | 0.77 | THRB (0.48) | MEN1KMT2AALDH1A1MAPTBLM | |
| SCHEMBL2859639 | 0.76 | THRB (0.53) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL29413087 | 0.75 | THRB (0.50) | MEN1KMT2AALDH1A1MAPTBLM | |
| SCHEMBL2868709 | 0.73 | THRB (0.53) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9106113 | 0.72 | THRB (0.53) | MEN1KMT2AALDH1A1MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743523-B1 | Dye-based reference material, preparation and use thereof | BAYER AG (US) | 2002-08-28 | — | — | EP | claimed |
| EP-3894839-B1 | SYSTEM SUITABILITY METHOD FOR USE WITH PROTEIN CONCENTRATION DETERMINATION BY SLOPE | AMGEN INC (US) | 2026-01-28 | — | — | EP | disclosed |
| US-12000775-B2 | System suitability method for use with protein concentration determination by slope | AMGEN INC. (US) | 2024-06-04 | — | — | US | disclosed |
| EP-3519060-B1 | ORAL CARE COMPOSITIONS WITH INCREASED WHITENING EFFICACY | COLGATE PALMOLIVE CO (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2022188373-A1 | METHOD FOR DETECTING WATER-SOLUBLE ANIONIC SYNTHETIC PIGMENT IN FOOD | 广州市食品检验所（广州市酒类检测中心） | 2022-09-15 | — | — | WO | disclosed |
| EP-2710996-B1 | Sunscreen compositions comprising colour pigments | BASF SE (DE) | 2022-08-17 | — | — | EP | disclosed |
| US-11400032-B2 | Tooth whitening oral care product with core shell silica particles | COLGATE-PALMOLIVE COMPANY (US) | 2022-08-02 | — | — | US | disclosed |
| US-11384033-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | BASF SE (DE) | 2022-07-12 | — | — | US | disclosed |
| US-20220146413-A1 | SYSTEM SUITABILITY METHOD FOR USE WITH PROTEIN CONCENTRATION DETERMINATION BY SLOPE | AMGEN INC. (US) | 2022-05-12 | — | — | US | disclosed |
| CN-109890464-B | Oral care compositions with increased whitening efficacy | 高露洁-棕榄公司 | 2022-04-05 | — | — | CN | disclosed |
| US-6057078-A | PHOTOGRAPHY | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| US-5807604-A | SOLVENT MIXTURE COMPRISING TARTRAZINE YELLOW AND AQUEOUS ETHYLENE GLYCOL | PRESERVED BOTANICALS, INC. (US) | 1998-09-15 | — | — | US | disclosed |
| US-5693361-A | SOAKING NATURAL PLANT MATERIALS IN AQUEOUS SOLUTION CONTAINING ETHYLENE GLYCOL AND DISSOLVED CARBON DIOXIDE, FOR DECORATIONS | PRESERVED BOTANICALS, INC. (US) | 1997-12-02 | — | — | US | disclosed |
| CN-1160058-A | Borate photoinitiators from polyboranes | CIBA GEIGY AG (CH) | 1997-09-24 | — | — | CN | disclosed |
| EP-0569488-B1 | BORATE COINITIATORS FOR PHOTOPOLYMERIZABLE COMPOSITIONS | DU PONT (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0569488-A1 | BORATE COINITIATORS FOR PHOTOPOLYMERIZABLE COMPOSITIONS. | DU PONT (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0286250-B1 | COMPOSITION FOR THE TREATMENT OF PERIODONTAL DISEASE | BTG INTERNATIONAL LIMITED (GB) | 1993-08-04 | — | — | EP | disclosed |
| WO-1992013900-A1 | BORATE COINITIATORS FOR PHOTOPOLYMERIZABLE COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-20 | — | — | WO | disclosed |
| US-5087451-A | Applying nontoxic lewis acid and redox dye | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-02-11 | — | — | US | disclosed |
| EP-0286250-A1 | Composition for the treatment of periodontal disease | BTG INTERNATIONAL LIMITED (GB) | 1988-10-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11384033-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | SLC14A1, XDH, PNP | PPARG 3624/4885MEN1 4263/4885KMT2A 2627/4885 |
| US-11400032-B2 | Tooth whitening oral care product with core shell silica particles | CBFB, IK, PWWP2B | PPARG 3527/4885MEN1 4481/4885KMT2A 2893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.