Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.70 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.61 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067395 | 1.00 | PTGS1 (0.70) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL346451 | 1.00 | PTGS1 (0.70) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL17433875 | 0.92 | PTGS1 (0.70) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL29449890 | 0.92 | PTGS1 (0.70) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL2898626 | 0.91 | PTGS1 (0.65) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL11867151 | 0.91 | PTGS1 (0.65) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL7081152 | 0.91 | PTGS1 (0.68) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL7081151 | 0.91 | PTGS1 (0.68) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL4158582 | 0.91 | PTGS1 (0.68) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| SCHEMBL4158575 | 0.91 | PTGS1 (0.68) | PTGS1GSTK1GLO1NOD1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| WO-2024204791-A1 | METHOD FOR PRODUCING METHYL COMPOUND | 三菱ケミカル株式会社 | 2024-10-03 | — | — | WO | claimed |
| US-20240011058-A1 | CANNABIDIOLIC ACID (CBDA) SYNTHASE VARIANTS, AND MANUFACTURE AND USE THEREOF | TEEWINOT LIFE SCIENCES CORP (US) | 2024-01-11 | — | — | US | claimed |
| US-20230407239-A1 | TETRAHYDROCANNABINOLIC ACID (THCA) SYNTHASE VARIANTS, AND MANUFACTURE AND USE THEREOF | TEEWINOT LIFE SCIENCES CORP (US) | 2023-12-21 | — | — | US | claimed |
| US-11753663-B2 | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing adipate, 6-aminocaproate, hexamethylenediamine or caprolactam related thereto | GENOMATICA, INC. (US) | 2023-09-12 | — | — | US | claimed |
| US-11535874-B2 | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing succinate related thereto | GENOMATICA, INC. (US) | 2022-12-27 | — | — | US | claimed |
| CN-115521880-A | Methanol-free culture method of methylotrophic yeast for biosynthesis of value-added products | 生物促进及生物合成咨询有限公司 | 2022-12-27 | — | — | CN | claimed |
| WO-2022103950-A1 | CANNABIDIOLIC ACID (CBDA) SYNTHASE VARIANTS, AND MANUFACTURE AND USE THEREOF | TEEWINOT LIFE SCIENCES CORPORATION (US) | 2022-05-19 | — | — | WO | claimed |
| WO-2022103938-A1 | TETRAHYDROCANNABINOLIC ACID (THCA) SYNTHASE VARIANTS, AND MANUFACTURE AND USE THEREOF | TEEWINOT LIFE SCIENCES CORPORATION (US) | 2022-05-19 | — | — | WO | claimed |
| US-20210032632-A1 | MATERIALS AND METHODS FOR THE BIOSYNTHESIS OF SEVEN CARBON CHEMICALS IN THE PRESENCE OF METHANOL OXIDATION | INV NYLON CHEMICALS AMERICAS, LLC | 2021-02-04 | — | — | US | claimed |
| WO-2018022613-A1 | MATERIALS AND METHODS FOR THE BIOSYNTHESIS OF SEVEN CARBON CHEMICALS IN THE PRESENCE OF METHANOL OXIDATION | INVISTA TEXTILES (U.K.) LIMITED (GB) | 2018-02-01 | — | — | WO | claimed |
| US-20180023088-A1 | MATERIALS AND METHODS FOR THE BIOSYNTHESIS OF SEVEN CARBON CHEMICALS IN THE PRESENCE OF METHANOL OXIDATION | INVISTA North America S.à.r.l | 2018-01-25 | — | — | US | claimed |
| US-20260130873-A1 | COMPOSITIONS AND METHODS FOR TREATING HOMOCYSTINURIA AND OTHER CONDITIONS | THE REGENTS OF THE UNIV OF COLORADO A BODY CORPORATE (US) | 2026-05-14 | — | — | US | disclosed |
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | GENOMATICA, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250388910-A1 | METHODS FOR ENHANCING MICROBIAL PRODUCTION OF SPECIFIC LENGTH FATTY ALCOHOLS IN THE PRESENCE OF METHANOL | AGAIN BIO APS (DK) | 2025-12-25 | — | — | US | disclosed |
| US-12465579-B2 | Compositions and methods for treating homocystinuria and other conditions | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2025-11-11 | — | — | US | disclosed |
| US-20020128205-A1 | Modulating nitric oxide acitivity with glutathione-dependent formaldehyde dehydrogenase (GS-FDH); for treatment of asthma and impotency, angina, hypertension, and cancer; enzyme inhibitors | DUKE UNIVERSITY OFFICE OF SCIENCE AND TECHNOLOGY (US) | 2002-09-12 | — | — | US | disclosed |
| US-20020119507-A1 | Determination method of biological component and reagent kit used therefor | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2002-08-29 | — | — | US | disclosed |
| WO-2002055018-A2 | INHIBITING GS-FDH TO MODULATE NO BIOACTIVITY | DUKE UNIVERSITY (US) | 2002-07-18 | — | — | WO | disclosed |
| EP-1213358-A2 | Method and kit for the determination of a biological component | Toyo Boseki Kabushiki Kaisha (JP) | 2002-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | ALDOA, FDPS, DERA | PTGS1 1671/4885GSTK1 998/4885GLO1 258/4885 |
| US-20260130873-A1 | COMPOSITIONS AND METHODS FOR TREATING HOMOCYSTINURIA AND OTHER CONDITIONS | SLC6A12, CTH, SLC6A6 | PTGS1 2904/4885GSTK1 1188/4885GLO1 81/4885 |
| US-20250388910-A1 | METHODS FOR ENHANCING MICROBIAL PRODUCTION OF SPECIFIC LENGTH FATTY ALCOHOLS IN THE PRESENCE OF METHANOL | ADH5, ADH1C, ADH1A | PTGS1 1485/4885GSTK1 1371/4885GLO1 343/4885 |
| US-20020128205-A1 | Modulating nitric oxide acitivity with glutathione-dependent formaldehyde dehydrogenase (GS-FDH); for treatment of asthma and impotency, angina, hypertension, and cancer; enzyme inhibitors | GGH, GSS, GSR | PTGS1 18/4885GSTK1 53/4885GLO1 91/4885 |
| US-11535874-B2 | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing succinate related thereto | ME3, ME2, ME1 | PTGS1 526/4885GSTK1 775/4885GLO1 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.