Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 4/20 | 0.34 |
| ▸ | CBLB | Q13191 | 3/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL19207252 | 1.00 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2KMT2AATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL127417 | 0.93 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL26669425 | 0.93 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATMALDH1A1 | |
| Acetic Acid SCHEMBL475885 | 0.92 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2KMT2AATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL31470991 | 0.91 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2KMT2AATMALDH1A1 | |
| SCHEMBL192702 | 0.91 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2KMT2AATMALDH1A1 | |
| Iodide SCHEMBL2254575 | 0.90 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATMALDH1A1 | |
| Water SCHEMBL2355003 | 0.90 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATMALDH1A1 | |
| Iodide SCHEMBL17105877 | 0.90 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATMALDH1A1 | |
| Bromide SCHEMBL475865 | 0.90 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240041743-A1 | SYNERGISTIC TETRAPEPTIDE COMBINATION | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2024-02-08 | — | — | US | disclosed |
| US-11633407-B2 | Botanical extracts and compounds from Schinus plants and methods of use | EMORY UNIVERSITY (US) | 2023-04-25 | — | — | US | disclosed |
| US-20230112887-A1 | Pentagalloyl Glucose Derived from Schinus Plants and Methods of Use | UNIV EMORY (US) | 2023-04-13 | — | — | US | disclosed |
| EP-4110269-A1 | PENTAGALLOYL GLUCOSE DERIVED FROM SCHINUS PLANTS AND METHODS OF USE | Emory University (US) | 2023-01-04 | — | — | EP | disclosed |
| CN-107913194-B | Ultraviolet radiation absorbing polymer composition | 强生消费者公司 | 2022-06-28 | — | — | CN | disclosed |
| US-20220152048-A1 | Botanical Extracts and Compounds from Castanea Plants and Methods of Use | UNIV EMORY (US) | 2022-05-19 | — | — | US | disclosed |
| WO-2022008732-A1 | ENHANCING THE ACTIVITY OF ANTIMICROBIAL PRESERVATIVES | BASF SE (DE) | 2022-01-13 | — | — | WO | disclosed |
| US-20210315906-A1 | Botanical Extracts and Compounds from Schinus Plants and Methods of Use | EMORY UNIVERSITY | 2021-10-14 | — | — | US | disclosed |
| CN-108289819-B | Anhydrous spot-removing composition containing phenolic compounds | 杭州鼎智生物医药有限公司 | 2021-09-10 | — | — | CN | disclosed |
| EP-3481365-B1 | SOLUBILIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS | BASF SE (DE) | 2021-09-08 | — | — | EP | disclosed |
| WO-2005042828-A2 | STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-05-12 | — | — | WO | disclosed |
| WO-2005039610-A1 | A PLANT EXTRACT AND ITS PHARMACEUTICAL AND COSMETIC USE | COGNIS FRANCE, S.A.S. (FR) | 2005-05-06 | — | — | WO | disclosed |
| EP-1494641-A2 | AMINOPHENYLBENZOTHIAZOLE COMPOUNDS | Ciba SC Holding AG (CH) | 2005-01-12 | — | — | EP | disclosed |
| US-20040234480-A1 | Use of oligomeric proanthrocyanidins | COGNIS FRANCE, S.A. (FR) | 2004-11-25 | — | — | US | disclosed |
| US-20040102355-A1 | Quaternary surfactants | COGNIS IP MANAGEMENT GMBH (DE) | 2004-05-27 | — | — | US | disclosed |
| US-20040047832-A1 | Cosmetic and/or dermopharmaceutical preparations containing leaf extracts of the plant argania spinosa | COGNIS FRANCE S.A. (FR) | 2004-03-11 | — | — | US | disclosed |
| WO-2003086341-A2 | AMINOPHENYLBENZOTHIAZOLE COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-10-23 | — | — | WO | disclosed |
| US-20030175366-A1 | Plant Extracts and Methods of Treating Skin Therewith | COGNIS FRANCE, S.A. (FR) | 2003-09-18 | — | — | US | disclosed |
| US-20030161847-A1 | Use of hydroxyethers in cosmetic and pharmaceutical preparations | COGNIS IP MANAGEMENT GMBH (DE) | 2003-08-28 | — | — | US | disclosed |
| US-6313085-B1 | COMPOSITION COMPRISING ALKYL ETHER SULFATE AND ALKYL SULFATE HAVING HIGH SOLIDS CONTENT; PERSONAL CARE COMPOSITIONS | COGNIS DEUTSCHLAND GMBH (DE) | 2001-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040234480-A1 | Use of oligomeric proanthrocyanidins | CUTA, GLA, CASP10 | ACHE 1435/4885ZDHHC20 2202/4885ZDHHC2 3569/4885 |
| US-20030161847-A1 | Use of hydroxyethers in cosmetic and pharmaceutical preparations | CYP8B1, SQLE, HSD17B7 | ACHE 4098/4885ZDHHC20 305/4885ZDHHC2 369/4885 |
| US-20220152048-A1 | Botanical Extracts and Compounds from Castanea Plants and Methods of Use | CUTA, CES2, CYP17A1 | ACHE 183/4885ZDHHC20 3496/4885ZDHHC2 3560/4885 |
| US-20210315906-A1 | Botanical Extracts and Compounds from Schinus Plants and Methods of Use | BROX, C5, SYMPK | ACHE 341/4885ZDHHC20 1740/4885ZDHHC2 1458/4885 |
| US-11633407-B2 | Botanical extracts and compounds from Schinus plants and methods of use | BROX, C5, SYMPK | ACHE 341/4885ZDHHC20 1740/4885ZDHHC2 1458/4885 |
| US-20040047832-A1 | Cosmetic and/or dermopharmaceutical preparations containing leaf extracts of the plant argania spinosa | CUTA, ARG1, ARG2 | ACHE 769/4885ZDHHC20 451/4885ZDHHC2 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.