Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.31 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3662730 | 0.96 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL10385511 | 0.79 | ALDH1A1 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL20923 | 0.77 | TSHR (0.54) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL9639404 | 0.76 | ZDHHC20 (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28293126 | 0.76 | TSHR (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL11598614 | 0.76 | TSHR (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL2331157 | 0.76 | ALDH1A1 (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Potassium Ion SCHEMBL21777261 | 0.75 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL31296560 | 0.75 | ALDH1A1 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28598554 | 0.74 | ZDHHC20 (0.56) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975286-B2 | Cement slurries with salt-tolerant fluid loss additives and methods relating thereto | HALLIBURTON ENERGY SERVICES, INC. (US) | 2021-04-13 | — | — | US | claimed |
| US-20170183558-A1 | Cement Slurries With Salt-Tolerant Fluid Loss Additives And Methods Relating Thereto | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-06-29 | — | — | US | claimed |
| WO-2016032494-A1 | CEMENT SLURRIES WITH SALT-TOLERANT FLUID LOSS ADDITIVES AND METHODS RELATING THERETO | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-03-03 | — | — | WO | claimed |
| US-20250032398-A1 | HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF | ISP INVESTMENTS LLC (US) | 2025-01-30 | — | — | US | disclosed |
| US-10975286-B2 | Cement slurries with salt-tolerant fluid loss additives and methods relating thereto | HALLIBURTON ENERGY SERVICES, INC. (US) | 2021-04-13 | — | — | US | disclosed |
| US-20170183558-A1 | Cement Slurries With Salt-Tolerant Fluid Loss Additives And Methods Relating Thereto | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-06-29 | — | — | US | disclosed |
| WO-2016032494-A1 | CEMENT SLURRIES WITH SALT-TOLERANT FLUID LOSS ADDITIVES AND METHODS RELATING THERETO | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-03-03 | — | — | WO | disclosed |
| EP-1781717-B1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL AG & CO KGAA (DE) | 2012-11-07 | — | — | EP | disclosed |
| EP-2215134-A2 | REDUCTION OF THE FORMATION OF BIOFILM BY MEANS OF MULTIFUNCTIONAL COPOLYMERS | Henkel AG & Co. KGaA (DE) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009071451-A2 | REDUCTION OF THE FORMATION OF BIOFILM BY MEANS OF MULTIFUNCTIONAL COPOLYMERS | HENKEL AG & CO. KGAA (DE) | 2009-06-11 | — | — | WO | disclosed |
| EP-1781717-A1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006005358-A1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-01-19 | — | — | WO | disclosed |
| EP-0455846-B1 | Method for reconstituting superabsorbent polymer fines | STOCKHAUSEN LOUISIANA LIMITED (US) | 2000-07-12 | — | — | EP | disclosed |
| US-5908908-A | EMULSION ACRYLIC INTERPOLYMER CONTAINING 05 TO 1% BY WEIGHT OF AT LEAST ONE (METH)ACRYLIC OR VINYL MONOMER CONTAINING A UREIDO GROUP | ELF ATOCHEM S.A. (FR) | 1999-06-01 | — | — | US | disclosed |
| EP-0455846-A1 | Method for reconstituting superabsorbent polymer fines | NALCO CHEMICAL COMPANY (US) | 1991-11-13 | — | — | EP | disclosed |
| US-4970267-A | WETTING, GELATION, GRINDING, DRYING | NALCO CHEMICAL COMPANY (US) | 1990-11-13 | — | — | US | disclosed |
| US-4950692-A | FROM STARCH GRAFT OR SYNTHETIC POLYMERS BY WETTING WITH WATER, TO FORM GEL, GRINDING, AND DRYING | NALCO CHEMICAL COMPANY (US) | 1990-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250032398-A1 | HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF | PCNA, ADSL, APH1B | CA12 2460/4885CA2 4795/4885TSHR 3587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.