SCHEMBL3749003

SCHEMBL3749003

CC(C)(C)OC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.40
CTSK P43235 6/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
CYP2D6 P10635 1/20 0.36
CTSS P25774 5/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
PLK1 P53350 2/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
KLK7 P49862 1/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13265369 1.00 CYP1A2 (0.40) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL30561557 0.95 CTSK (0.38) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL14708937 0.95 CYP1A2 (0.40) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL17911923 0.95 CYP1A2 (0.40) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL30678053 0.94 HTT (0.39) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL20355987 0.93 CTSK (0.42) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL18932981 0.91 CTSK (0.37) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL18206896 0.91 CTSK (0.37) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL18206898 0.91 CTSK (0.37) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL12657517 0.90 CYP1A2 (0.40) CYP1A2CYP2C9CYP2C19HTTCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-12612420-B2 Arginase inhibitors and methods of use thereof MOLECURE S.A. (PL) 2026-04-28 US disclosed
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms Pharmapotheca A, Inc. 2025-07-03 US disclosed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 US disclosed
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 US disclosed
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms Pharmapotheca A Inc. (US) 2025-01-28 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-12077606-B2 Cyclic peptide analogs and conjugates thereof SIRENAS LLC (US) 2024-09-03 US disclosed
EP-4364754-A2 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2024-05-08 EP disclosed
US-20240058450-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2024-02-22 US disclosed
US-9562069-B2 Selective caspase inhibitors and uses thereof NEW WORLD LABORATORIES INC. (CA) 2017-02-07 US disclosed
US-20160339117-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC. (US) 2016-11-24 US disclosed
US-20160326182-A1 METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE CURIA BUFFALO R&D, LLC 2016-11-10 US disclosed
US-20160326182-A1 METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE CURIA BUFFALO R&D, LLC 2016-11-10 US disclosed
WO-2016094509-A1 BCL XL INHIBITORY COMPOUNDS HAVING LOW CELL PERMEABILITY AND ANTIBODY DRUG CONJUGATES INCLUDING THE SAME ABBVIE INC. (US) 2016-06-16 WO disclosed
US-20140038903-A1 Selective Cysteine Protease Inhibitors and Uses Thereof NEW WORLD LABORATORIES, INC. (CA) 2014-02-06 US disclosed
US-20140038903-A1 Selective Cysteine Protease Inhibitors and Uses Thereof NEW WORLD LABORATORIES, INC. (CA) 2014-02-06 US disclosed
US-8362015-B2 Aminoacyl prodrug derivatives and medicaments for treatment of thromboembolic disorders BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-01-29 US disclosed
EP-2084154-B1 AMINOACYL PRODRUG DERIVATIVES AND MEDICAMENTS FOR TREATMENT OF THROMBOEMBOLIC DISORDERS BAYER IP GMBH (DE) 2012-11-21 EP disclosed
US-20100292230-A1 Aminoacyl prodrug derivatives and medicaments for treatment of thromboembolic disorders BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 CYP1A2 3799/4885CYP2C9 2088/4885CYP2C19 2123/4885
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms SLC6A3, CES2, SLC6A2 CYP1A2 56/4885CYP2C9 4/4885CYP2C19 8/4885
US-20160326182-A1 METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE OPRM1, OPRK1, OPRD1 CYP1A2 176/4885CYP2C9 179/4885CYP2C19 387/4885
US-20160339117-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 CYP1A2 4558/4885CYP2C9 2902/4885CYP2C19 2944/4885
US-12077606-B2 Cyclic peptide analogs and conjugates thereof VIP, NGLY1, GRPR CYP1A2 4822/4885CYP2C9 4191/4885CYP2C19 3756/4885
US-20140038903-A1 Selective Cysteine Protease Inhibitors and Uses Thereof SERPINB1, SERPINE1, CASP5 CYP1A2 2156/4885CYP2C9 1709/4885CYP2C19 2513/4885
US-12612420-B2 Arginase inhibitors and methods of use thereof ARG1, ARG2, ARGLU1 CYP1A2 2718/4885CYP2C9 1861/4885CYP2C19 2588/4885
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 CYP1A2 62/4885CYP2C9 4/4885CYP2C19 9/4885
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 CYP1A2 4558/4885CYP2C9 2902/4885CYP2C19 2944/4885
US-20240058450-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 CYP1A2 4558/4885CYP2C9 2902/4885CYP2C19 2944/4885
US-20100292230-A1 Aminoacyl prodrug derivatives and medicaments for treatment of thromboembolic disorders AADAC, AADAT, DNPEP CYP1A2 122/4885CYP2C9 58/4885CYP2C19 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.