Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A known ✓ | P35498 | 1/20 | 0.51 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.51 |
| ▸ | SCN2A known ✓ | Q99250 | 1/20 | 0.51 |
| ▸ | SCN3A known ✓ | Q9NY46 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 11/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | PRNP | P04156 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30611012 | 0.95 | KDM4E (0.62) | KDM4ECYP2C9HPGDDUSP3L3MBTL1 | |
| SCHEMBL48846 | 0.95 | KDM4E (0.62) | KDM4ECYP2C9HPGDDUSP3L3MBTL1 | |
| Lithium Ion SCHEMBL18104080 | 0.92 | KDM4E (0.59) | KDM4ECYP2C9HPGDDUSP3L3MBTL1 | |
| Pyrazine SCHEMBL9102227 | 0.89 | KDM4E (0.57) | KDM4ECYP2C9HPGDDUSP3L3MBTL1 | |
| SCHEMBL49291 | 0.83 | PIM1 (0.59) | KDM4EHPGDL3MBTL1PIM1KDM1A | |
| SCHEMBL31384188 | 0.83 | PIM1 (0.59) | KDM4EHPGDL3MBTL1PIM1KDM1A | |
| SCHEMBL3774114 | 0.82 | PIM1 (0.58) | KDM4EHPGDL3MBTL1PIM1KDM1A | |
| SCHEMBL208025 | 0.80 | PIM1 (0.79) | KDM4EPIM1KDM1ASIGMAR1SLC22A1 | |
| SCHEMBL30115197 | 0.78 | MEN1 (0.58) | KDM4EHPGDL3MBTL1PIM1KDM1A | |
| SCHEMBL48681 | 0.78 | MEN1 (0.58) | KDM4EHPGDL3MBTL1PIM1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11112366-B2 | Reagent and kit for enhancing chemiluminescent reaction | NATIONAL TAIWAN OCEAN UNIVERSITY (TW) | 2021-09-07 | — | — | US | claimed |
| US-20200309707-A1 | REAGENT AND KIT FOR ENHANCING CHEMILUMINESCENT REACTION | NATIONAL TAIWAN OCEAN UNIVERSITY (TW) | 2020-10-01 | — | — | US | claimed |
| US-10711185-B2 | Reagent and kit for performing chemiluminescent reaction | BIO-HELIX CO., LTD. (TW) | 2020-07-14 | — | — | US | claimed |
| EP-1950207-B1 | Preparation of high purity phenothiazine n-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase activity | CYANAGEN SRL (IT) | 2012-06-20 | — | — | EP | claimed |
| US-7855287-B2 | Preparation of high purity phenothiazine N-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase activity | CYANAGEN SRL (IT) | 2010-12-21 | — | — | US | claimed |
| EP-1950207-A1 | Preparation of high purity phenothiazine n-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase activity | Cyanagen Srl (IT) | 2008-07-30 | — | — | EP | claimed |
| US-20080176251-A1 | Preparation of high purity phenothiazine N-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase acitivity | CYANAGEN SRL (IT) | 2008-07-24 | — | — | US | claimed |
| US-11112366-B2 | Reagent and kit for enhancing chemiluminescent reaction | NATIONAL TAIWAN OCEAN UNIVERSITY (TW) | 2021-09-07 | — | — | US | disclosed |
| US-20200309707-A1 | REAGENT AND KIT FOR ENHANCING CHEMILUMINESCENT REACTION | NATIONAL TAIWAN OCEAN UNIVERSITY (TW) | 2020-10-01 | — | — | US | disclosed |
| US-10711185-B2 | Reagent and kit for performing chemiluminescent reaction | BIO-HELIX CO., LTD. (TW) | 2020-07-14 | — | — | US | disclosed |
| EP-1950207-B1 | Preparation of high purity phenothiazine n-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase activity | CYANAGEN SRL (IT) | 2012-06-20 | — | — | EP | disclosed |
| US-7855287-B2 | Preparation of high purity phenothiazine N-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase activity | CYANAGEN SRL (IT) | 2010-12-21 | — | — | US | disclosed |
| EP-1950207-A1 | Preparation of high purity phenothiazine n-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase activity | Cyanagen Srl (IT) | 2008-07-30 | — | — | EP | disclosed |
| US-20080176251-A1 | Preparation of high purity phenothiazine N-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase acitivity | CYANAGEN SRL (IT) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11112366-B2 | Reagent and kit for enhancing chemiluminescent reaction | MPO, LPO, KIT | SCN1A 4683/4885PDE3A 1337/4885SCN2A 4740/4885 |
| US-20080176251-A1 | Preparation of high purity phenothiazine N-alkylsulfonates and their use in chemiluminescent assays for the measurement of peroxidase acitivity | LPO, ARSA, SULT1E1 | SCN1A 312/4885PDE3A 278/4885SCN2A 659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.