SCHEMBL378759

SCHEMBL378759

Cc1cccc(CCCNC(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.62
RAB9A P51151 4/20 0.62
KMT2A Q03164 3/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
LMNA P02545 2/20 0.62
MEN1 O00255 1/20 0.58
POLB P06746 2/20 0.57
KDM4E B2RXH2 1/20 0.57
HDAC3 O15379 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC10 Q969S8 1/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
MTNR1A P48039 1/20 0.52
MTNR1B P49286 1/20 0.52
ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11895626 0.90 NPC1 (0.65) NPC1RAB9AKMT2ALMNAMEN1
SCHEMBL20725102 0.89 MTNR1A (0.67) NPC1RAB9AKMT2ASMN1; SMN2LMNA
SCHEMBL27129577 0.83 HDAC6 (0.55) NPC1RAB9APOLBKDM4EHDAC6
SCHEMBL7503367 0.83 NPC1 (0.51) NPC1RAB9AKMT2ASMN1; SMN2LMNA
SCHEMBL164622 0.82 L3MBTL1 (0.72) NPC1RAB9AKMT2ASMN1; SMN2POLB
SCHEMBL1794493 0.82 NPC1 (0.52) NPC1RAB9APOLBKDM4EMTNR1A
SCHEMBL951922 0.82 MAOA (0.53) NPC1RAB9AKMT2ASMN1; SMN2LMNA
SCHEMBL24279418 0.82 TACR1 (0.61) NPC1RAB9AKMT2ASMN1; SMN2LMNA
SCHEMBL13725463 0.81 MTNR1A (0.79) KMT2ASMN1; SMN2MEN1HDAC1HDAC6
SCHEMBL16155837 0.81 MAPT (0.59) NPC1RAB9AKMT2ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 500 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2683239-A1 USE OF LIPOCHITO-OLIGOSACCHARIDE COMPOUNDS FOR SAFEGUARDING SEED SAFETY OF TREATED SEEDS Bayer Intellectual Property GmbH (DE) 2014-01-15 EP claimed
US-20130345058-A1 USE OF LIPOCHITO-OLIGOSACCHARIDE COMPOUNDS FOR SAFEGUARDING SEED SAFETY OF TREATED SEEDS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-12-26 US claimed
WO-2012120105-A1 USE OF LIPOCHITO-OLIGOSACCHARIDE COMPOUNDS FOR SAFEGUARDING SEED SAFETY OF TREATED SEEDS BAYER CROPSCIENCE AG (DE) 2012-09-13 WO claimed
EP-2114118-B1 SAFEGUARDING SEED SAFETY OF TREATED SEEDS BAYER CROPSCIENCE AG (DE) 2012-09-12 EP claimed
EP-2213168-A1 Pesticidal combination of active agents Bayer CropScience AG (DE) 2010-08-04 EP claimed
US-20100130365-A1 SAFEGUARDING SEED SAFETY OF TREATED SEEDS BAYER CROPSCIENCE AG (DE) 2010-05-27 US claimed
EP-2000029-A1 Insecticide and fungicide active agent combinations Bayer CropScience AG (DE) 2008-12-10 EP claimed
EP-1967057-A1 Safeguarding seed safety of treated seeds Bayer CropScience AG (DE) 2008-09-10 EP claimed
US-4226883-A Carbamate derivatives and method for manufacture thereof YAMAMOTO IZURU 1980-10-07 US claimed
CN-113784952-B Esters of non-aromatic heterocyclic compounds having nematicidal activity, their agronomic compositions and uses thereof 高文作物保护公司 2024-07-19 CN disclosed
CN-113382996-B Theophylline derivatives with nematicidal activity, agronomic compositions and related uses 高文作物保护公司 2024-07-16 CN disclosed
US-20220204540-A1 ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2022-06-30 US disclosed
US-20220104495-A1 THEOPHYLLINE DERIVATIVES WITH NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE USE BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2022-04-07 US disclosed
EP-3962900-A1 ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF ISAGRO S.p.A. (IT) 2022-03-09 EP disclosed
WO-2000020415-A1 PHENYLACETIC ACID HETEROCYCLYL AMIDES HAVING AN INSECTICIDAL EFFECT BAYER AKTIENGESELLSCHAFT (DE) 2000-04-13 WO disclosed
WO-2000015622-A1 ISOTHIAZOLE CARBOXYLIC ACID AMIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-03-23 WO disclosed
WO-2000010970-A1 METHOXIMINOPHENYLACETIC ACID AMIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-03-02 WO disclosed
WO-2000008003-A2 FUNGICIDE THIOPHENDIOXIMETHER BAYER AKTIENGESELLSCHAFT (DE) 2000-02-17 WO disclosed
WO-2000003995-A1 DIPHENYLIMIDAZOLINES BAYER AKTIENGESELLSCHAFT (DE) 2000-01-27 WO disclosed
WO-1999016748-A1 UTILIZING SPIROCYCLIC PHENYL KETO-ENOLS AS PESTICIDES AND HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-04-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204540-A1 ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF ACHE, CYP51A1, DNPH1 NPC1 931/4885RAB9A 611/4885KMT2A 1357/4885
US-20100130365-A1 SAFEGUARDING SEED SAFETY OF TREATED SEEDS TUBA3C, TUBB3, TUBA1C NPC1 1691/4885RAB9A 1203/4885KMT2A 3297/4885
US-20130345058-A1 USE OF LIPOCHITO-OLIGOSACCHARIDE COMPOUNDS FOR SAFEGUARDING SEED SAFETY OF TREATED SEEDS FUT6, B3GNT2, FUT5 NPC1 247/4885RAB9A 1872/4885KMT2A 3526/4885
US-20220104495-A1 THEOPHYLLINE DERIVATIVES WITH NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE USE ACHE, XDH, TYMP NPC1 2161/4885RAB9A 2155/4885KMT2A 1851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.