Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.49 |
| ▸ | ME2 | P23368 | 1/20 | 0.48 |
| ▸ | ME1 | P48163 | 1/20 | 0.48 |
| ▸ | ME3 | Q16798 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824036 | 0.96 | L3MBTL1 (0.55) | OPRM1PKMTMEM97ME2ME1 | |
| SCHEMBL3860666 | 0.87 | RORC (0.45) | OPRM1TMEM97ME2ME1ME3 | |
| SCHEMBL3823818 | 0.82 | AGER (0.48) | OPRM1ALDH1A1LMNARORC | |
| SCHEMBL3829302 | 0.79 | ALDH1A1 (0.50) | OPRM1TMEM97ME2ME1ME3 | |
| SCHEMBL3066199 | 0.79 | DRD2 (0.43) | L3MBTL1RAB9ASMN1; SMN2RORC | |
| SCHEMBL3827832 | 0.75 | AGER (0.53) | TMEM97ME2ME1ME3L3MBTL1 | |
| SCHEMBL8179598 | 0.75 | HTR2A (0.57) | OPRM1L3MBTL1ALDH1A1TSHRRAB9A | |
| SCHEMBL4737202 | 0.75 | SLC6A9 (0.43) | L3MBTL1ALDH1A1TSHR | |
| SCHEMBL4738099 | 0.74 | RORC (0.36) | L3MBTL1ALDH1A1MAPTSMN1; SMN2RORC | |
| SCHEMBL3827281 | 0.74 | AGER (0.54) | ME2ME1ME3L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |