Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 4/20 | 0.42 |
| ▸ | GABRD | O14764 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.42 |
| ▸ | GABRE | P78334 | 4/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095143 | 0.84 | MPO (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL895172 | 0.79 | PIK3CG (0.66) | PIK3CGPSMB8PSMB5KDM4ES1PR3 | |
| SCHEMBL2490866 | 0.76 | SMN1; SMN2 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2541637 | 0.76 | KDM4E (0.59) | PIK3CGGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9898426 | 0.76 | PIK3CG (0.61) | PIK3CGGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11170826 | 0.76 | PIK3CG (0.43) | PIK3CGPSMB8PSMB5KDM4EKMT2A | |
| SCHEMBL5542616 | 0.76 | GABRP (0.42) | PIK3CGGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2550867 | 0.76 | ESR1 (0.58) | PIK3CGKDM4EMAPT | |
| SCHEMBL20552113 | 0.76 | PIK3CG (0.43) | PIK3CGPSMB8PSMB5DAGLAKDM4E | |
| SCHEMBL15157800 | 0.76 | NPC1 (0.58) | PIK3CGPSMB8PSMB5KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572893-A1 | Fluor-benzoxazolyloxyacetamides | BAYER AG (DE) | 1993-12-08 | — | — | EP | claimed |
| US-12606551-B2 | Salt of tetrahydroisoquinoline derivative, preparation method therefor, and medical use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2026-04-21 | — | — | US | disclosed |
| CN-117120423-B | Indolylamine 2, 3-dioxygenase inhibitors, methods of preparing the same, and pharmaceutical compositions containing the same | 柳韩洋行 | 2026-02-27 | — | — | CN | disclosed |
| US-12297209-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2025-05-13 | — | — | US | disclosed |
| US-12268694-B2 | Combination pharmaceutical agents as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2025-04-08 | — | — | US | disclosed |
| CN-113880825-B | Tetrahydroisoquinoline derivative salt, preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119059967-A | Diaryl amine compound with affinity with Tau protein, and preparation method and application thereof | 北京师范大学 | 2024-12-03 | — | — | CN | disclosed |
| US-20240360155-A1 | Benzodiazepine Derivatives as RSV Inhibitors | ENANTA PHARM INC (US) | 2024-10-31 | — | — | US | disclosed |
| US-20240174636-A1 | NOVEL INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2024-05-30 | — | — | US | disclosed |
| WO-2024084447-A2 | AZETIDINYL BENZOXAZOLE COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS | DONG-A ST CO., LTD. (KR) | 2024-04-25 | — | — | WO | disclosed |
| US-7307095-B2 | Osteoporosis; antiarthritic agents; antidiabetic agents; antiinflammatory agents; Alzheimer's disease; shock; central nervous stsrem disorders; anticancer agents; multiple sclerosis, (S)-2-(Benzooxazol-2-ylamino)-3-cyclohexyl-N-[2-(5-fluoro-2,3-dihydro-indol-1-yl)-ethyl]-propionamide | IRM LLC (BM) | 2007-12-11 | — | — | US | disclosed |
| US-20070123523-A1 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2007-05-31 | — | — | US | disclosed |
| US-7173051-B2 | Inhibitors of cathepsin S | IRM, LLC (BM) | 2007-02-06 | — | — | US | disclosed |
| US-20050049244-A1 | Inhibitors of cathepsin S | IRM LLC (BM) | 2005-03-03 | — | — | US | disclosed |
| WO-2004112709-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-12-29 | — | — | WO | disclosed |
| EP-0883611-B1 | AZOLYL PIPERAZINYL PHENYL OXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-0883611-A1 | AZOLYL PIPERAZINYL PHENYL OXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-16 | — | — | EP | disclosed |
| US-5736545-A | ADMINISTERING TO TREAT BACTERIAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| WO-1997030981-A1 | AZOLYL PIPERAZINYL PHENYL OXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |
| EP-0572893-A1 | Fluor-benzoxazolyloxyacetamides | BAYER AG (DE) | 1993-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174636-A1 | NOVEL INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | IDO1, IDO2, INMT | PIK3CG 2990/4885GABRP 3708/4885GABRD 3965/4885 |
| US-20240360155-A1 | Benzodiazepine Derivatives as RSV Inhibitors | GABRA5, GABRA1, GABBR2 | PIK3CG 2957/4885GABRP 11/4885GABRD 44/4885 |
| US-20050049244-A1 | Inhibitors of cathepsin S | CTSS, CTSB, CTSZ | PIK3CG 2676/4885GABRP 2825/4885GABRD 4652/4885 |
| US-12297209-B2 | Benzodiazepine derivatives as RSV inhibitors | GABRA5, GABRA1, GABBR2 | PIK3CG 2957/4885GABRP 11/4885GABRD 44/4885 |
| US-12268694-B2 | Combination pharmaceutical agents as RSV inhibitors | ACE, ACE2, SPCS3 | PIK3CG 1395/4885GABRP 1313/4885GABRD 3961/4885 |
| US-20070123523-A1 | INHIBITORS OF CATHEPSIN S | CTSS, CTSB, CTSZ | PIK3CG 2676/4885GABRP 2825/4885GABRD 4652/4885 |
| US-12606551-B2 | Salt of tetrahydroisoquinoline derivative, preparation method therefor, and medical use thereof | SLC5A2, SLC5A1, SLC5A11 | PIK3CG 738/4885GABRP 1030/4885GABRD 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.