SCHEMBL40179

SCHEMBL40179

CC(=O)/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(\C)C#CC1=C(C)C(=O)C(O)CC1(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.56
LMNA P02545 3/20 0.38
HIF1A Q16665 3/20 0.38
GMNN O75496 2/20 0.38
PMP22 Q01453 2/20 0.38
TSHR P16473 1/20 0.38
APEX1 P27695 1/20 0.38
ALOX15 P16050 3/20 0.37
ALDH1A1 P00352 6/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
PTGS1 P23219 5/20 0.33
DRD3 P35462 2/20 0.31
SLCO1B3 Q9NPD5 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31
RXRA P19793 5/20 0.30
RARA P10276 4/20 0.30
RARB P10826 4/20 0.30
RARG P13631 4/20 0.30
RXRB P28702 2/20 0.30
RXRG P48443 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18582451 1.00 MAPT (0.56) MAPTLMNAHIF1AGMNNPMP22
SCHEMBL2837999 0.94 MAPT (0.61) MAPTLMNAHIF1AGMNNPMP22
SCHEMBL30002204 0.94 MAPT (0.61) MAPTLMNAHIF1AGMNNPMP22
SCHEMBL2832598 0.88 MAPT (0.76) MAPTLMNAHIF1AGMNNPMP22
SCHEMBL545399 0.88 MAPT (0.76) MAPTLMNAHIF1AGMNNPMP22
SCHEMBL2840387 0.87 MAPT (0.53) MAPTLMNAHIF1AGMNNPMP22
SCHEMBL2836348 0.85 ALOX15 (0.54) MAPTLMNAHIF1AGMNNPMP22
SCHEMBL2952241 0.82 ALOX15 (0.49) MAPTLMNAHIF1AGMNNPMP22
SCHEMBL2841013 0.79 MAPT (0.67) MAPTLMNAHIF1AGMNNPMP22
SCHEMBL42982 0.79 MAPT (0.67) MAPTLMNAHIF1AGMNNPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013144595-A1 PERIDININ-CHLOROPHYLL BINDING PROTEINS PROTEIN TECHNOLOGIES LIMITED (GB) 2013-10-03 WO claimed
WO-2024141918-A1 USE OF MICROALGAE AND MICROALGAE DERIVED COMPONENTS IN CULTIVATED FOOD PRODUCTION WEFORESEA LTD. (IL) 2024-07-04 WO disclosed
US-20240191053-A1 SYSTEMS, MICROORGANISMS, OR METHODS FOR WASTE PET VALORIZATION WASHINGTON UNIVERSITY (US) 2024-06-13 US disclosed
US-20240165036-A1 ENCAPSULATED VITAMIN D Nulixir Inc. 2024-05-23 US disclosed
US-20240065262-A1 COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE ROBBINS JEFFREY HANSON (US) 2024-02-29 US disclosed
US-20240033287-A1 ANTIMICROBIAL CLAY COMPOSITIONS AND METHODS OF USING ELANCO US INC (US) 2024-02-01 US disclosed
US-20240024358-A1 THERAPEUTIC CLAY COMPOSITIONS AND METHODS OF USING ELANCO US, Inc. 2024-01-25 US disclosed
US-20230404126-A1 ENCAPSULATED PRECURSORS OF NICOTINAMIDE ADENINE DINUCLEOTIDE AND METHODS OF MAKING THE SAME Nulixir Inc. 2023-12-21 US disclosed
US-20230371551-A1 FEED ADDITIVE COMPOSITIONS ELANCO US INC (US) 2023-11-23 US disclosed
EP-3716958-B1 COMPOSITION FOR THE TREATMENT OF DYSBIOSIS OF THE INTESTINAL MICROBIOTA DERMAPHARM AG (DE) 2023-10-18 EP disclosed
US-20050065097-A1 Carotenoid ether analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury CARDAX PHARMACEUTICALS, INC. 2005-03-24 US disclosed
US-20050059635-A1 Carotenoid ester analogs or derivatives for controlling C-reactive protein levels CARDAX PHARMACEUTICALS, INC. 2005-03-17 US disclosed
US-20050059659-A1 Carotenoid analogs or derivatives for controlling C-reactive protein levels CARDAX PHARMACEUTICALS, INC. 2005-03-17 US disclosed
US-20050049248-A1 Carotenoid ether analogs or derivatives for controlling C-reactive protein levels CARDAX PHARMACEUTICALS, INC. 2005-03-03 US disclosed
US-20050037995-A1 Carotenoid ester analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury CARDAX PHARMA, INC. 2005-02-17 US disclosed
US-20050026874-A1 Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease CARDAX PHARMACEUTICALS, INC. 2005-02-03 US disclosed
US-20050009930-A1 Carotenoid analogs or derivatives for controlling connexin 43 expression CARDAX PHARMA, INC. 2005-01-13 US disclosed
US-20050009788-A1 Carotenoid ester analogs or derivatives for controlling connexin 43 expression CARDAX PHARMACEUTICALS, INC. 2005-01-13 US disclosed
US-20050009758-A1 Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease CARDAX PHARMA, INC. 2005-01-13 US disclosed
US-20050004235-A1 Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease CARDAX PHARMACEUTICALS, INC. 2005-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050037995-A1 Carotenoid ester analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury CPT1A, TXNRD2, PC MAPT 4758/4885LMNA 1111/4885HIF1A 1596/4885
US-20050009788-A1 Carotenoid ester analogs or derivatives for controlling connexin 43 expression GJA1, GJB2, CRY1 MAPT 4813/4885LMNA 29/4885HIF1A 2345/4885
US-20050009930-A1 Carotenoid analogs or derivatives for controlling connexin 43 expression GJA1, GJB2, CRY1 MAPT 4766/4885LMNA 34/4885HIF1A 2311/4885
US-20050059635-A1 Carotenoid ester analogs or derivatives for controlling C-reactive protein levels TTPA, PROC, RBP4 MAPT 3857/4885LMNA 3024/4885HIF1A 4080/4885
US-20050059659-A1 Carotenoid analogs or derivatives for controlling C-reactive protein levels RBP1, PROC, RBP4 MAPT 3997/4885LMNA 2708/4885HIF1A 3872/4885
US-20050026874-A1 Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease GYS2, HCCS, CPT1A MAPT 3961/4885LMNA 716/4885HIF1A 4172/4885
US-20050049248-A1 Carotenoid ether analogs or derivatives for controlling C-reactive protein levels PROC, TTPA, CYC1 MAPT 4035/4885LMNA 2351/4885HIF1A 4422/4885
US-20050065097-A1 Carotenoid ether analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury TXNRD2, GPX4, PC MAPT 4751/4885LMNA 868/4885HIF1A 1781/4885
US-20050009758-A1 Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease NFE2L2, GPX4, CYP11B2 MAPT 4360/4885LMNA 685/4885HIF1A 2693/4885
US-20050004235-A1 Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease GYS2, HCCS, CPT1A MAPT 3908/4885LMNA 870/4885HIF1A 4038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.