Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | MC1R | Q01726 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042762 | 0.92 | GAA (0.34) | CTSBCTSSCTSKMAPK1ALDH1A1 | |
| SCHEMBL4041433 | 0.91 | ALDH1A1 (0.35) | CTSBCTSSALDH1A1POLBCTSL | |
| SCHEMBL4047478 | 0.89 | MC4R (0.37) | CTSBCTSSCTSKACECTSL | |
| SCHEMBL4045047 | 0.89 | CTSL (0.37) | CTSBCTSSCTSKPOLBMAPT | |
| SCHEMBL4047615 | 0.88 | CTSB (0.38) | CTSBCTSSCTSKACEFKBP1A | |
| SCHEMBL4046533 | 0.87 | MAPK1 (0.36) | CTSBCTSSCTSKMAPK1ALDH1A1 | |
| SCHEMBL4044768 | 0.85 | CTSL (0.44) | CTSBCTSSCTSKCTSL | |
| SCHEMBL4048142 | 0.84 | GAA (0.36) | CTSBCTSSCTSKALDH1A1MAPT | |
| SCHEMBL4050328 | 0.83 | SCN9A (0.39) | CTSBCTSSCTSKACEFKBP1A | |
| SCHEMBL4044603 | 0.83 | MC4R (0.37) | CTSBCTSSCTSKPOLBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |