Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 19/20 | 0.44 |
| ▸ | CTSS | P25774 | 14/20 | 0.44 |
| ▸ | CTSB | P07858 | 7/20 | 0.44 |
| ▸ | CTSK | P43235 | 18/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044198 | 0.93 | CTSL (0.42) | CTSLCTSSCTSBCTSKCTSV | |
| SCHEMBL4044603 | 0.90 | MC4R (0.37) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4045047 | 0.90 | CTSL (0.37) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4041433 | 0.88 | ALDH1A1 (0.35) | CTSLCTSSCTSB | |
| SCHEMBL4041003 | 0.87 | CTSL (0.39) | CTSLCTSSCTSBCTSKCTSV | |
| SCHEMBL4043722 | 0.86 | CTSK (0.40) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4045912 | 0.85 | ITGA4 (0.34) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4042676 | 0.85 | CTSB (0.36) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4045610 | 0.85 | POLB (0.33) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4047478 | 0.85 | MC4R (0.37) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |