Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.35 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.35 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | MC1R | Q01726 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042529 | 0.93 | BCL2 (0.38) | ACEBCL2GPR132CMKLR2CMKLR1 | |
| SCHEMBL4047882 | 0.90 | F2 (0.36) | ACEBCL2GPR132CMKLR2CMKLR1 | |
| SCHEMBL4044160 | 0.90 | CTSB (0.37) | ACEGPR132CMKLR2CMKLR1CTSK | |
| SCHEMBL4042585 | 0.90 | USP30 (0.39) | BCL2CTSKELANEMC4RMC3R | |
| SCHEMBL4043465 | 0.90 | MC4R (0.41) | ACEBCL2GPR132CTSKELANE | |
| SCHEMBL4043350 | 0.88 | HTRA1 (0.35) | CTSKMC4RMC3RMC1RCTSB | |
| SCHEMBL4045571 | 0.87 | CTSK (0.46) | CTSKELANECTSBCTSSCTSL | |
| SCHEMBL4043596 | 0.87 | ELANE (0.38) | GPR132CTSKELANEMC4RMC3R | |
| SCHEMBL4051296 | 0.85 | CTSL (0.39) | CTSKCTSBCTSSCTSLCTSV | |
| SCHEMBL4042165 | 0.85 | EPHX1 (0.37) | ACEGPR132CMKLR2CMKLR1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |