Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 8/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044157 | 0.90 | CNR1 (0.38) | ITGA4ITGB7POLBCTSKITGB1 | |
| SCHEMBL4045610 | 0.90 | POLB (0.33) | POLBF12CTSKCAPN1F10 | |
| SCHEMBL4041433 | 0.88 | ALDH1A1 (0.35) | ITGA4ITGB7POLBF12ITGB1 | |
| SCHEMBL4046036 | 0.88 | P2RX7 (0.36) | ITGA4ITGB7CTSKITGB1ACE | |
| SCHEMBL4044768 | 0.85 | CTSL (0.44) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4041901 | 0.83 | P2RX7 (0.39) | ITGA4ITGB7CTSKITGB1P2RX7 | |
| SCHEMBL4044603 | 0.82 | MC4R (0.37) | ITGA4ITGB7POLBCTSKCTSL | |
| SCHEMBL4045047 | 0.82 | CTSL (0.37) | ITGA4ITGB7POLBF12CTSK | |
| SCHEMBL4043833 | 0.82 | F10 (0.36) | ITGA4ITGB7CTSKITGB1F10 | |
| SCHEMBL4041712 | 0.82 | ITGA4 (0.40) | ITGA4ITGB7CTSKITGB1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |