Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4078418 | 0.87 | HTT (0.43) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL4084062 | 0.86 | ALDH1A1 (0.51) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL4083862 | 0.85 | TAS1R3 (0.38) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL4078532 | 0.84 | RAB9A (0.39) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL4078553 | 0.84 | KDM4E (0.44) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL4083252 | 0.84 | PTK2 (0.37) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL4083791 | 0.84 | LMNA (0.44) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL4087253 | 0.84 | CASP3 (0.38) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL4081200 | 0.83 | MAPT (0.45) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL4091779 | 0.83 | LMNA (0.44) | RAB9AALDH1A1KDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058315-A1 | 1H-Furo[3,2-C]Pyrazoles active as aurora kinase inhibitors | Nerviano Medical Sciences S.r.l. (IT) | 2009-05-13 | — | — | EP | disclosed |