Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433142 | 0.81 | NPC1 (0.48) | POLBMAPTMAOBHTT | |
| SCHEMBL23258867 | 0.77 | MAPT (0.59) | L3MBTL1MAPTMAPK1TDP1MAPK14 | |
| SCHEMBL6641881 | 0.75 | LMNA (0.44) | L3MBTL1NSD2ABL1PPARGRIN1 | |
| SCHEMBL7958052 | 0.74 | L3MBTL1 (0.54) | L3MBTL1NSD2ABL1PPARGRIN1 | |
| SCHEMBL11250024 | 0.74 | ALDH1A1 (0.47) | POLBL3MBTL1MAPTTDP1 | |
| SCHEMBL2116326 | 0.73 | L3MBTL1 (0.54) | POLBL3MBTL1NSD2ABL1PPARG | |
| SCHEMBL27773465 | 0.73 | L3MBTL1 (0.42) | POLBL3MBTL1NSD2ABL1PPARG | |
| SCHEMBL71120 | 0.73 | GSTP1 (0.44) | POLBL3MBTL1NSD2ABL1PPARG | |
| SCHEMBL9653085 | 0.73 | LOXL2 (0.48) | POLBL3MBTL1NSD2ABL1PPARG | |
| SCHEMBL9012908 | 0.73 | L3MBTL1 (0.43) | POLBL3MBTL1NSD2ABL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687298-B1 | CYCLOALKYL DERIVATIVES OF 3-HYDROXY-4-PYRIDINONES | APOTEX INC (CA) | 2012-12-26 | — | — | EP | claimed |
| US-20090170850-A1 | Cycloalkyl derivatives of 3-hydroxy-4-pyridinones | APOTEX INC. | 2009-07-02 | — | — | US | claimed |
| EP-1687298-A4 | CYCLOALKYL DERIVATIVES OF 3-HYDROXY-4-PYRIDINONES | APOTEX INC (CA) | 2007-10-17 | — | — | EP | claimed |
| US-20070082904-A1 | Cycloalkyl derivatives of 3-hydroxy-4-pyridinones field of the invention | APOTEX INC. (CA) | 2007-04-12 | — | — | US | claimed |
| EP-1687298-A1 | CYCLOALKYL DERIVATIVES OF 3-HYDROXY-4-PYRIDINONES | Apotex Inc. (CA) | 2006-08-09 | — | — | EP | claimed |
| WO-2005049609-A1 | CYCLOALKYL DERIVATIVES OF 3-HYDROXY-4-PYRIDINONES | APOTEX INC. (CA) | 2005-06-02 | — | — | WO | claimed |
| US-12606766-B2 | Multipurpose oxypyridinones and their functional use-4 | INFINEUM INTERNATIONAL LIMITED (US) | 2026-04-21 | — | — | US | disclosed |
| US-12606765-B2 | Multipurpose oxypyridinones and their functional use—1 | INFINEUM INTERNATIONAL LIMITED (US) | 2026-04-21 | — | — | US | disclosed |
| US-12503666-B2 | Multipurpose oxypyridinones and their functional use-2 | INFINEUM INTERNATIONAL LIMITED (US) | 2025-12-23 | — | — | US | disclosed |
| CN-119176807-A | Alpha-hydroxy ketone nitrogen-containing fused ring compound and application thereof | 北京英飞智药科技有限公司 | 2024-12-24 | — | — | CN | disclosed |
| US-20240294840-A1 | MULTIPURPOSE OXYPYRIDINONES AND THEIR FUNCTIONAL USE-2 | INFINEUM INTERNATIONAL LIMITED (US) | 2024-09-05 | — | — | US | disclosed |
| US-20240294841-A1 | MULTIPURPOSE OXYPYRIDINONES AND THEIR FUNCTIONAL USE-3 | INFINEUM INTERNATIONAL LIMITED (US) | 2024-09-05 | — | — | US | disclosed |
| US-20240294842-A1 | MULTIPURPOSE OXYPYRIDINONES AND THEIR FUNCTIONAL USE-4 | INFINEUM INTERNATIONAL LIMITED (US) | 2024-09-05 | — | — | US | disclosed |
| EP-1687298-B1 | CYCLOALKYL DERIVATIVES OF 3-HYDROXY-4-PYRIDINONES | APOTEX INC (CA) | 2012-12-26 | — | — | EP | disclosed |
| WO-2001017497-A1 | DEPIGMENTING COMPOSITIONS | GHISALBERTI CARLO (BR) | 2001-03-15 | — | — | WO | disclosed |
| EP-0619808-B1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS CHELATING AGENTS | BTG INT LTD (GB) | 1998-11-25 | — | — | EP | disclosed |
| US-5480894-A | 3-hydroxypyridin-4-one derivatives as chelating agents | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0619808-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS CHELATING AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1994-10-19 | — | — | EP | disclosed |
| WO-1994004498-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS CHELATING AGENTS | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1994-03-03 | — | — | WO | disclosed |
| EP-0243924-A2 | 2-Oxo-1-(substituted phosphorous)azetidines | E.R. Squibb & Sons, Inc. (US) | 1987-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294840-A1 | MULTIPURPOSE OXYPYRIDINONES AND THEIR FUNCTIONAL USE-2 | SIGMAR1, OXGR1, OPRM1 | POLB 116/4885L3MBTL1 4369/4885NSD2 162/4885 |
| US-20090170850-A1 | Cycloalkyl derivatives of 3-hydroxy-4-pyridinones | HAMP, C1S, C1R | POLB 2089/4885L3MBTL1 3178/4885NSD2 4806/4885 |
| US-12606766-B2 | Multipurpose oxypyridinones and their functional use-4 | PHOSPHO1, SIGMAR1, SGMS1 | POLB 878/4885L3MBTL1 1658/4885NSD2 1866/4885 |
| US-20070082904-A1 | Cycloalkyl derivatives of 3-hydroxy-4-pyridinones field of the invention | HAMP, C1S, SLC40A1 | POLB 2822/4885L3MBTL1 3789/4885NSD2 4805/4885 |
| US-12606765-B2 | Multipurpose oxypyridinones and their functional use—1 | SIGMAR1, PHOSPHO1, SGMS1 | POLB 898/4885L3MBTL1 772/4885NSD2 2819/4885 |
| US-12503666-B2 | Multipurpose oxypyridinones and their functional use-2 | SIGMAR1, OXGR1, OPRM1 | POLB 116/4885L3MBTL1 4369/4885NSD2 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.