SCHEMBL4154758

SCHEMBL4154758

N[C@@H](CSC(CC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 1/20 0.49
BHMT Q93088 2/20 0.41
ALDH1A1 P00352 3/20 0.40
GRIK1 P39086 2/20 0.40
GRIK2 Q13002 2/20 0.40
GRM1 Q13255 2/20 0.40
GRM2 Q14416 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GRM8 O00222 1/20 0.40
GRM6 O15303 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GSR P00390 1/20 0.40
CYP1A2 P05177 1/20 0.40
GRM5 P41594 1/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20362609 1.00 CPB1 (0.49) CPB1BHMTALDH1A1GRIK1GRIK2
SCHEMBL20362608 1.00 CPB1 (0.49) CPB1BHMTALDH1A1GRIK1GRIK2
SCHEMBL1478672 1.00 CPB1 (0.49) CPB1BHMTALDH1A1GRIK1GRIK2
SCHEMBL18818108 0.82 BHMT (0.38) CPB1BHMTALDH1A1GRIK1GRIK2
SCHEMBL4164642 0.82 CPB1 (0.45) CPB1BHMTALDH1A1KDM4ESLC1A1
SCHEMBL26752387 0.81 KIF11 (0.38) ALDH1A1GRIK1GRIK2ARG1ARG2
SCHEMBL18818107 0.81 KIF11 (0.38) ALDH1A1GRIK1GRIK2ARG1ARG2
SCHEMBL16054622 0.81 ALDH1A1 (0.38) CPB1BHMTALDH1A1GRIK1GRIK2
SCHEMBL4164445 0.81 ALDH1A1 (0.43) CPB1BHMTALDH1A1GRIK1KDM4E
SCHEMBL4169490 0.80 GRM8 (0.57) BHMTGRIK1GRIK2GRM1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119104734-A Molecular marker for diagnosis and prognosis of brain metastasis of lung cancer 中国医学科学院肿瘤医院 2024-12-10 CN claimed
EP-1933642-B1 SALT ENHANCING COMPOUNDS AND USE HOFMANN THOMAS FRANK (DE) 2011-12-21 EP claimed
US-20090155440-A1 Salt Enhancing Compounds and Use GIVAUDAN SA (CH) 2009-06-18 US claimed
EP-1933642-A1 SALT ENHANCING COMPOUNDS AND USE Thomas Frank Hofmann & Andreas Dunkel Inst. für Lebensmittelchemie (DE) 2008-06-25 EP claimed
WO-2007042274-A1 SALT ENHANCING COMPOUNDS AND USE THOMAS FRANK HOFMANN & ANDREAS DUNKEL (DE) 2007-04-19 WO claimed
US-20260027162-A1 MUCISPIRILLUM COMPOSITIONS AND CANCER TREATMENT METHODS THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-01-29 US disclosed
EP-4684030-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2026-01-28 EP disclosed
EP-3806661-B1 USE OF ANTAGONISTS OF T2R54 FIRMENICH INCORPORATED (US) 2025-07-02 EP disclosed
EP-4566459-A2 ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF Firmenich Incorporated (US) 2025-06-11 EP disclosed
EP-4555326-A2 MUCISPIRILLUM COMPOSITIONS AND CANCER TREATMENT METHODS THEREOF President And Fellows Of Harvard College (US) 2025-05-21 EP disclosed
US-12295396-B2 Antagonists of T2R54 and compositions and uses thereof FIRMENICH INCORPORATED (US) 2025-05-13 US disclosed
CN-119264123-A Antagonists of T2R54, compositions thereof and uses thereof 弗门尼舍公司 2025-01-07 CN disclosed
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-04-06 US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 US disclosed
EP-1933642-B1 SALT ENHANCING COMPOUNDS AND USE HOFMANN THOMAS FRANK (DE) 2011-12-21 EP disclosed
US-20090155440-A1 Salt Enhancing Compounds and Use GIVAUDAN SA (CH) 2009-06-18 US disclosed
EP-1933642-A1 SALT ENHANCING COMPOUNDS AND USE Thomas Frank Hofmann & Andreas Dunkel Inst. für Lebensmittelchemie (DE) 2008-06-25 EP disclosed
WO-2007042274-A1 SALT ENHANCING COMPOUNDS AND USE THOMAS FRANK HOFMANN & ANDREAS DUNKEL (DE) 2007-04-19 WO disclosed
EP-0308983-A2 NMR imaging with Mn(II) coordination compositions SALUTAR, INC. (US) 1989-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027162-A1 MUCISPIRILLUM COMPOSITIONS AND CANCER TREATMENT METHODS THEREOF SAAL1, CD74, MUC1 CPB1 2128/4885BHMT 2019/4885ALDH1A1 1202/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 CPB1 4570/4885BHMT 616/4885ALDH1A1 1490/4885
US-12295396-B2 Antagonists of T2R54 and compositions and uses thereof TAS2R50, TAS2R30, TAS2R60 CPB1 4225/4885BHMT 3211/4885ALDH1A1 3663/4885
US-20090155440-A1 Salt Enhancing Compounds and Use TAS1R1, TAS2R41, TAS2R40 CPB1 1244/4885BHMT 1578/4885ALDH1A1 2141/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D CPB1 3001/4885BHMT 1457/4885ALDH1A1 1029/4885
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 CPB1 3269/4885BHMT 3319/4885ALDH1A1 3880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.