Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 5/20 | 0.47 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10804583 | 0.97 | CA4 (0.44) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Zinc Ion SCHEMBL29443816 | 0.93 | CA4 (0.41) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL16504394 | 0.93 | CA4 (0.41) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL30542449 | 0.93 | CA4 (0.41) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL30697531 | 0.93 | CA4 (0.41) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL30776751 | 0.93 | CA4 (0.41) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL7522991 | 0.93 | CA4 (0.41) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL30045530 | 0.93 | CA4 (0.41) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL16504393 | 0.93 | CA4 (0.41) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Lithium Ion SCHEMBL29934334 | 0.93 | CA4 (0.41) | CA4CASP1FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221417-B2 | METHOD OF MINERAL OIL PRODUCTION | BASF SE (DE) | 2025-12-10 | — | — | EP | claimed |
| EP-3500247-B1 | IMMEDIATE RELEASE TABLET OF A BENZOTHIOPHENE COMPOUND | H E X A L AG (DE) | 2020-05-27 | — | — | EP | claimed |
| EP-3500247-A1 | IMMEDIATE RELEASE TABLET OF A BENZOTHIOPHENE COMPOUND | H e x a l Aktiengesellschaft (DE) | 2019-06-26 | — | — | EP | claimed |
| WO-2018033481-A1 | IMMEDIATE RELEASE TABLET OF A BENZOTHIOPHENE COMPOUND | H E X A L AKTIENGESELLSCHAFT (DE) | 2018-02-22 | — | — | WO | claimed |
| US-20130190373-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREVENTION OR TREATMENT OF SYSTEMIC DISEASES IN CATS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2013-07-25 | — | — | US | claimed |
| US-20130143937-A1 | CHLORTHALIDONE COMBINATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-06 | — | — | US | claimed |
| EP-1648515-B1 | CHLORTHALIDONE COMBINATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-11-21 | — | — | EP | claimed |
| US-20100003341-A1 | COMPOSITION WITH A BACTERICIDAL, FUNGICIDAL, VIRICIDAL AND INSECTICIDAL ACTION AND COMPOSITION ACTING AS A REPELLENT | BESENDORFER THOMAS | 2010-01-07 | — | — | US | claimed |
| US-20090104262-A9 | Chlorthalidone combinations | BRAND GERRIT | 2009-04-23 | — | — | US | claimed |
| US-20070160665-A1 | Chlorthalidone combinations | BRAND GERRIT | 2007-07-12 | — | — | US | claimed |
| EP-1648515-A1 | CHLORTHALIDONE COMBINATIONS | Boehringer Ingelheim International GmbH (DE) | 2006-04-26 | — | — | EP | claimed |
| WO-2005014043-A1 | CHLORTHALIDONE COMBINATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-02-17 | — | — | WO | claimed |
| US-4304680-A | Laundry soap | COLGATE-PALMOLIVE COMPANY (US) | 1981-12-08 | — | — | US | claimed |
| US-3962106-A | DETERGENTS | LEVER BROTHERS COMPANY (US) | 1976-06-08 | — | — | US | claimed |
| US-3941723-A | Crystallized alkali metal silicate with sequestering agents | PHILADELPHIA QUARTZ COMPANY (US) | 1976-03-02 | — | — | US | claimed |
| US-20260042948-A1 | SURFACTANT COMPOSITION FOR DIRECT EMULSION DRILLING FLUID | SCHLUMBERGER TECHNOLOGY CORP (US) | 2026-02-12 | — | — | US | disclosed |
| EP-4687818-A1 | COMPOSITION COMPRISING AN ALKYL- AND/OR ALKENYLGLYCOSIDE | KAO CORPORATION, S.A. (ES) | 2026-02-11 | — | — | EP | disclosed |
| US-3936448-A | DETERGENTS, BUILDERS | LEVER BROTHERS COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
| US-3935206-A | Sulfosuccinate derivatives as detergent builders | LEVER BROTHERS COMPANY (US) | 1976-01-27 | — | — | US | disclosed |
| US-3717676-A | SYNTHESIS OF OXYCARBOXYLIC ACID SALTS | AIR PROD & CHEM | 1973-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190373-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREVENTION OR TREATMENT OF SYSTEMIC DISEASES IN CATS | AGTR1, AGTR2, AGT | CA4 1649/4885CA2 403/4885CA1 1718/4885 |
| US-20070160665-A1 | Chlorthalidone combinations | AGTR2, AGTR1, AGT | CA4 211/4885CA2 83/4885CA1 3068/4885 |
| US-20130143937-A1 | CHLORTHALIDONE COMBINATIONS | AGTR2, AGTR1, AGT | CA4 211/4885CA2 83/4885CA1 3068/4885 |
| US-20260042948-A1 | SURFACTANT COMPOSITION FOR DIRECT EMULSION DRILLING FLUID | DEGS1, DGAT1, DSG1 | CA4 1107/4885CA2 581/4885CA1 314/4885 |
| US-20090104262-A9 | Chlorthalidone combinations | AGTR2, AGTR1, AGT | CA4 211/4885CA2 83/4885CA1 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.