SCHEMBL4325880

SCHEMBL4325880

CCCCCCCCCCCCN(C(=O)C[N+](C)(C)C)[C@](CCCCCCCCCCCC)(CCC(=O)O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 3/20 0.37
PHF8 Q9UPP1 3/20 0.37
KDM4C Q9H3R0 2/20 0.37
GPR84 Q9NQS5 7/20 0.37
PPARG P37231 7/20 0.37
PPARD Q03181 7/20 0.37
PPARA Q07869 7/20 0.37
HDAC11 Q96DB2 5/20 0.37
TSHR P16473 4/20 0.37
PTPN1 P18031 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TLR2 O60603 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
FABP4 P15090 2/20 0.37
SLC22A6 Q4U2R8 1/20 0.37
SLC22A8 Q8TCC7 1/20 0.37
MEN1 O00255 1/20 0.37
ESR1 P03372 1/20 0.37
ALOX15 P16050 1/20 0.37
PDE4A P27815 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21048580 1.00 KDM5A (0.37) KDM5APHF8KDM4CGPR84PPARG
SCHEMBL4334125 1.00 KDM5A (0.37) KDM5APHF8KDM4CGPR84PPARG
Hydrochloric Acid SCHEMBL4290887 0.99 KDM5A (0.36) KDM5APHF8KDM4CGPR84PPARG
Hydrochloric Acid SCHEMBL9330621 0.99 KDM5A (0.36) KDM5APHF8KDM4CGPR84PPARG
Hydrochloric Acid SCHEMBL345724 0.99 KDM5A (0.36) KDM5APHF8KDM4CGPR84PPARG
Hydrochloric Acid SCHEMBL4293179 0.99 KDM5A (0.36) KDM5APHF8KDM4CGPR84PPARG
Hydrochloric Acid SCHEMBL4302158 0.92 EPHX2 (0.47) PPARGPPARDPPARAPTPN1ALDH1A1
Hydrochloric Acid SCHEMBL15948948 0.92 EPHX2 (0.47) PPARGPPARDPPARAPTPN1ALDH1A1
SCHEMBL4325883 0.90 KDM5A (0.36) KDM5APHF8KDM4CGPR84PPARG
SCHEMBL4334127 0.90 KDM5A (0.36) KDM5APHF8KDM4CGPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230035723-A1 Treatment of Pancreatic Cancer SYNCORE BIOTECHNOLOGY CO., LTD. (TW) 2023-02-02 US claimed
US-20220313608-A1 TREATMENT OF BREAST CANCER SYNCORE BIOTECHNOLOGY CO., LTD. (TW) 2022-10-06 US claimed
EP-3397244-B1 TREATMENT OF BREAST CANCER USING A COMBINATION OF A CATIONIC LIPOSOMAL FORMULATION OF TAXANE, A NON-LIPOSOMAL FORMULATION OF TAXANE AND A FURTHER ACTIVE AGENT SYNCORE BIOTECHNOLOGY CO LTD (TW) 2021-10-06 EP claimed
EP-1385933-B1 CULTURE MEDIUM FOR CELL GROWTH AND TRANSFECTION LIFE TECHNOLOGIES CORP (US) 2012-07-11 EP claimed
EP-0475178-B1 Liposome for entrapping gene, liposomal preparation and process for the manufacture of the preparation VITAMIN KENKYUSHO KK (JP) 1994-03-30 EP claimed
JP-9248182-A None JP disclosed
US-20260146070-A1 FUNCTIONALLY MODIFIED MAYTANSINOIDS AND COMPOSITIONS AND METHODS OF USE THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2026-05-28 US disclosed
US-20260124210-A1 THERAPEUTIC CONSTRUCTS FOR CO-DELIVERY OF ANTI-CANCER AGENT(S) AND IMMUNE CHECKPOINT INHIBITOR(S) OREGON HEALTH & SCIENCE UNIVERSITY (US) 2026-05-07 US disclosed
US-12605470-B2 Nanodroplet with layer-by-layer assembly ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-04-21 US disclosed
US-20260091038-A1 COMPOSITIONS AND METHODS FOR ENHANCING WNT SIGNALING FOR TREATING CANCER MASSACHUSETTS INST TECHNOLOGY (US) 2026-04-02 US disclosed
US-12582658-B2 Therapeutic constructs for co-delivery of anti-cancer agent(s) and immune checkpoint inhibitor(s) OREGON HEALTH & SCIENCE UNIVERSITY (US) 2026-03-24 US disclosed
US-20260071003-A1 COMPOSITIONS AND METHODS FOR DIRECTING APOLIPOPROTEIN L1 TO INDUCE MAMMALIAN CELL DEATH UNIV GEORGIA (US) 2026-03-12 US disclosed
EP-2034019-A1 COMPOSITION FOR NUCLEIC-ACID INTRODUCTION Hokkaido System Science Co., Ltd. (JP) 2009-03-11 EP disclosed
US-20090022782-A1 Blood Retainable Device Exhibiting Selective Degradability in Tumor Tissue NATIONAL UNIVERSITY CORP. HOKKAIDO UNIVERSITY (JP) 2009-01-22 US disclosed
EP-1862470-A1 ELEMENT RETAINED IN BLOOD SHOWING DEGRADABILITY SELECTIVELY IN TUMOR TISSUE National University Corporation Hokkaido University (JP) 2007-12-05 EP disclosed
US-20070112176-A1 Lipid membrane structure containing anti-mt-mmp monoclonal antibody DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-05-17 US disclosed
EP-1618897-A1 LIPID MEMBRANE STRUCTURE CONTAINING ANTI-MT-MMP MONOCLONAL ANTIBODY The University of Tokyo (JP) 2006-01-25 EP disclosed
CN-1506041-A Formulation and making process of genetic skin beautifying and whitening cosmetics 殷冬生 2004-06-23 CN disclosed
CN-1427008-A Method of designing and selecting natural siRNA as gene medicine and medicine formulation YIN DONGSHENG (CN) 2003-07-02 CN disclosed
JP-H09248182-A MULTILAMELLAR LIPOSOME FOR EMBEDDING PLASMID THEREIN OYO SEIKAGAKU KENKYUSHO 1997-09-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091038-A1 COMPOSITIONS AND METHODS FOR ENHANCING WNT SIGNALING FOR TREATING CANCER WNT3A, APC, WNT3 KDM5A 2866/4885PHF8 4450/4885KDM4C 3148/4885
US-12582658-B2 Therapeutic constructs for co-delivery of anti-cancer agent(s) and immune checkpoint inhibitor(s) PLK1, BUB1, WEE1 KDM5A 3724/4885PHF8 2559/4885KDM4C 3299/4885
US-20260071003-A1 COMPOSITIONS AND METHODS FOR DIRECTING APOLIPOPROTEIN L1 TO INDUCE MAMMALIAN CELL DEATH APOL1, APOB, LY96 KDM5A 4527/4885PHF8 3392/4885KDM4C 4624/4885
US-20260146070-A1 FUNCTIONALLY MODIFIED MAYTANSINOIDS AND COMPOSITIONS AND METHODS OF USE THEREOF NOS1, NOS3, NOX5 KDM5A 308/4885PHF8 1760/4885KDM4C 659/4885
US-20260124210-A1 THERAPEUTIC CONSTRUCTS FOR CO-DELIVERY OF ANTI-CANCER AGENT(S) AND IMMUNE CHECKPOINT INHIBITOR(S) PLK1, BUB1, BUB1B KDM5A 3763/4885PHF8 2787/4885KDM4C 3379/4885
US-12605470-B2 Nanodroplet with layer-by-layer assembly FLNB, FLNA, DAGLB KDM5A 3962/4885PHF8 3910/4885KDM4C 4196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.