Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 15/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236365 | 0.85 | ALDH1A1 (0.58) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL432773 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL432775 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3040698 | 0.79 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL496532 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8432960 | 0.77 | MEN1 (0.56) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15635741 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11603313 | 0.76 | GRIK1 (0.62) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9688887 | 0.75 | ACLY (0.64) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14521237 | 0.74 | GRIK1 (0.60) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588219-B1 | FILTER PLATE ARTICLE HAVING A WATER-ABSORBENT FILTER ASSEMBLY | NEOGEN FOOD SAFETY US HOLDCO CORP (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-2519821-B1 | MICROBIAL DETECTION ARTICLE | 3M INNOVATIVE PROPERTIES CO (US) | 2016-11-30 | — | — | EP | disclosed |
| CN-102958584-B | Filter plate article with water absorbent filter assembly | 3M INNOVATIVE PROPERTIES CO. (US) | 2015-10-21 | — | — | CN | disclosed |
| US-8906645-B2 | Microbial detection article having a water-absorbent filter assembly | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-12-09 | — | — | US | disclosed |
| CN-102713616-B | Microorganism detection article | 3M INNOVATIVE PROPERTIES CO. (US) | 2014-10-15 | — | — | CN | disclosed |
| US-8753834-B2 | Microbial detection article | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-06-17 | — | — | US | disclosed |
| US-20130316393-A1 | MICROBIAL DETECTION ARTICLE HAVING A WATER-ABSORBENT FILTER ASSEMBLY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-11-28 | — | — | US | disclosed |
| EP-2588219-A2 | FILTER PLATE ARTICLE HAVING A WATER-ABSORBENT FILTER ASSEMBLY | 3M Innovative Properties Company (US) | 2013-05-08 | — | — | EP | disclosed |
| CN-102958584-A | Filter plate article with water absorbent filter assembly | 3M INNOVATIVE PROPERTIES CO | 2013-03-06 | — | — | CN | disclosed |
| US-20120288888-A1 | MICROBIAL DETECTION ARTICLE | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2012-11-15 | — | — | US | disclosed |
| EP-0983375-B1 | METHODS AND DEVICES FOR DETECTING BACTERIOPHAGE | MINNESOTA MINING & MFG (US) | 2005-01-12 | — | — | EP | disclosed |
| US-6699685-B1 | (4),6,(7)-(DI,TRI)CHLOROINDOLYL-BETA-D-GALACTOSIDE INDICATORS; PRODUCE MAUVE OR MAGENTA PRECIPITATES WHEN REACTED UPON BY BETA-GALACTOSIDASE; CONTRASTS IN COLOR WITH GLUCURONIDASE SUBSTRATES | RCR SCIENTIFIC, INC. | 2004-03-02 | — | — | US | disclosed |
| US-6090541-A | Method and device for detecting bacteriophage using contrast-coloring and precipitable dyes | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0983375-A1 | METHODS AND DEVICES FOR DETECTING BACTERIOPHAGE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-08 | — | — | EP | disclosed |
| US-5958675-A | Method for detecting bacteria using bacteriophage, contrast-coloring dye and precipitable dye | 3M INNOVATIVE PROPERTIES COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1998048042-A2 | METHODS AND DEVICES FOR DETECTING BACTERIOPHAGE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-29 | — | — | WO | disclosed |
| US-5393662-A | Nutrient base medium containing chromogenic indolyl beta-galactosidase substrate forming insoluble colored compound upon reacting with beta-galactosidase | RCR SCIENTIFIC, INC. (US) | 1995-02-28 | — | — | US | disclosed |
| US-5364767-A | 6-chloroindole derivatives; colorimetric and quantitative analysis | RESEARCH ORGANICS, IN. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5358854-A | 6-chloroindolyl-beta-D-galactosie; 6-chloroindolyl-beta-D-gulcoronide 6-chloriindolyl-beta-D-gulcuronic acid monocyclohexylammonium salt | RESEARCH ORGANICS, INC. (US) | 1994-10-25 | — | — | US | disclosed |
| US-5210022-A | Substrates sensitive to beta-galactosidase and beta-glucuronidase, quantitative analysis | RCR SCIENTIFIC, INC. (US) | 1993-05-11 | — | — | US | disclosed |