Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.48 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.48 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.48 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.40 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.39 |
| ▸ | P2RY4 known ✓ | P51582 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 5/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220868 | 1.00 | RAD51 (0.54) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL893765 | 0.94 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL29737199 | 0.94 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL1169584 | 0.94 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL30532269 | 0.94 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL8410050 | 0.89 | RAD51 (0.55) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL4821260 | 0.89 | RAD51 (0.55) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL4821301 | 0.89 | RAD51 (0.55) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL8410035 | 0.89 | RAD51 (0.55) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL8012728 | 0.88 | RAD51 (0.54) | RAD51CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947483-B2 | Encapsulates | PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA (CH) | 2021-03-16 | — | — | US | claimed |
| US-10604728-B2 | Encapsulates | PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA (CH) | 2020-03-31 | — | — | US | claimed |
| US-20200071639-A1 | Encapsulates | PROCTER & GAMBLE INT OPERATIONS SA (CH) | 2020-03-05 | — | — | US | claimed |
| US-20170130172-A1 | ENCAPSULATES | PROCTER & GAMBLE (US) | 2017-05-11 | — | — | US | claimed |
| US-20160304817-A1 | ENCAPSULATES | PROCTER & GAMBLE (US) | 2016-10-20 | — | — | US | claimed |
| US-20160130537-A1 | ENCAPSULATES | PROCTER & GAMBLE (US) | 2016-05-12 | — | — | US | claimed |
| EP-2999776-A2 | ENCAPSULATES | The Procter & Gamble Company (US) | 2016-03-30 | — | — | EP | claimed |
| WO-2014189906-A2 | ENCAPSULATES | THE PROCTER & GAMBLE COMPANY (US) | 2014-11-27 | — | — | WO | claimed |
| WO-2014189980-A1 | ENCAPSULATES | PGIOSA (CH) | 2014-11-27 | — | — | WO | claimed |
| EP-2806018-A1 | ENCAPSULATES | The Procter & Gamble Company (US) | 2014-11-26 | — | — | EP | claimed |
| US-20140338134-A1 | ENCAPSULATES | THE PROCTER & GAMBLE COMPANY (US) | 2014-11-20 | — | — | US | claimed |
| EP-2126017-A1 | LIQUID LAUNDRY DETERGENT COMPOSITIONS COMPRISING PERFORMANCE BOOSTERS | The Procter and Gamble Company (US) | 2009-12-02 | — | — | EP | claimed |
| WO-2008114171-A1 | LIQUID LAUNDRY DETERGENT COMPOSITIONS COMPRISING PERFORMANCE BOOSTERS | THE PROCTER & GAMBLE COMPANY (US) | 2008-09-25 | — | — | WO | claimed |
| EP-1807496-A1 | FABRIC CARE COMPOSITIONS COMPRISING HUEING DYE | The Procter and Gamble Company (US) | 2007-07-18 | — | — | EP | claimed |
| WO-2006041954-A1 | FABRIC CARE COMPOSITIONS COMPRISING HUEING DYE | THE PROCTER & GAMBLE COMPANY (US) | 2006-04-20 | — | — | WO | claimed |
| US-20060079438-A1 | Fabric care compositions comprising hueing dye | PROCTER & GAMBLE COMPANY, THE | 2006-04-13 | — | — | US | claimed |
| US-11066657-B2 | Methods and compositions for stabilizing trans-splicing intein modified proteases | AGRIVIDA, INC (US) | 2021-07-20 | — | — | US | disclosed |
| US-10947483-B2 | Encapsulates | PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA (CH) | 2021-03-16 | — | — | US | disclosed |
| EP-2126017-A1 | LIQUID LAUNDRY DETERGENT COMPOSITIONS COMPRISING PERFORMANCE BOOSTERS | The Procter and Gamble Company (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008114171-A1 | LIQUID LAUNDRY DETERGENT COMPOSITIONS COMPRISING PERFORMANCE BOOSTERS | THE PROCTER & GAMBLE COMPANY (US) | 2008-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071639-A1 | Encapsulates | LIPA, TTPA, CHMP4B | CA12 1532/4885CA1 3244/4885CA2 3928/4885 |
| US-10947483-B2 | Encapsulates | LIPA, TTPA, CHMP4B | CA12 1532/4885CA1 3244/4885CA2 3928/4885 |
| US-11066657-B2 | Methods and compositions for stabilizing trans-splicing intein modified proteases | RTCB, RNASE1, CPSF1 | CA12 3521/4885CA1 3161/4885CA2 4434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.