Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.47 |
| ▸ | ATIC | P31939 | 1/20 | 0.53 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.53 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GLB1 | P16278 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865041 | 1.00 | ATIC (0.53) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL29723334 | 1.00 | ATIC (0.53) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL29637797 | 0.88 | SENP2 (0.69) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11345068 | 0.88 | SENP2 (0.69) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL13330173 | 0.85 | SENP2 (0.64) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL30034854 | 0.82 | SENP7 (0.46) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11751115 | 0.81 | ATIC (0.75) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL29371618 | 0.80 | CARM1 (0.47) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL4172944 | 0.80 | CARM1 (0.47) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL1618524 | 0.79 | ATIC (0.45) | ATICSUMO2SUMO1SENP7SENP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 597 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110589806-B | Efficient purification method of water-dispersible carbon nano material | 武汉大学 | 2022-08-05 | — | — | CN | claimed |
| EP-2889671-B1 | POLARIZING LENS FOR SUNGLASSES | MITSUBISHI GAS CHEMICAL CO (JP) | 2020-11-04 | — | — | EP | claimed |
| CN-110589806-A | Efficient purification method of water-dispersible carbon nano material | 武汉大学 | 2019-12-20 | — | — | CN | claimed |
| CN-106082419-B | Method and application of the degradation of macrocyclic amide metal complex containing organic pollutant wastewater | 北京服装学院 | 2019-05-31 | — | — | CN | claimed |
| CN-106082419-A | The degraded of macrocyclic amide metal complex contains method and the application of organic pollutant wastewater | 北京服装学院 | 2016-11-09 | — | — | CN | claimed |
| EP-1847571-B1 | Pigment umfassend ein plättchenförmiges Substrat | MERCK PATENT GMBH (DE) | 2013-12-25 | — | — | EP | claimed |
| CN-102732055-A | Multi-component chromogenic anion co-intercalation supramolecular structure pigment and preparation method thereof | UNIV BEIJING CHEMICAL | 2012-10-17 | — | — | CN | claimed |
| US-20110160399-A1 | HISTONE MODIFICATION INHIBITOR SPECIFIC TO TARGET GENE | NIHON UNIVERSITY (JP) | 2011-06-30 | — | — | US | claimed |
| EP-2311494-A1 | HISTONE MODIFICATION INHIBITOR SPECIFIC TO TARGET GENE | Nihon University (JP) | 2011-04-20 | — | — | EP | claimed |
| WO-2011008795-A1 | YELLOW INKJET INK HAVING IMPROVED PRINT QUALITY WITH POROUS PHOTO MEDIA | LEXMARK INTERNATIONAL, INC. (US) | 2011-01-20 | — | — | WO | claimed |
| US-20030035034-A1 | Ink set comprising dark yellow ink composition | SEIKO EPSON CORPORATION | 2003-02-20 | — | — | US | claimed |
| US-6521030-B1 | Set of ink jet inks for ink jet printing, comprising light magenta ink comprising high lightfastness magenta dye, further comprising dark magenta ink comprising high chroma magenta dye | HEWLETT-PACKARD COMPANY | 2003-02-18 | — | — | US | claimed |
| US-20020198294-A1 | Antireflective, layer-forming composition, layer configuration containing the antireflective layer, and process for producing the antireflective layer | POLARIS INNOVATIONS LIMITED (IE) | 2002-12-26 | — | — | US | claimed |
| US-20020059884-A1 | Ink composition for ink-jet printers | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2002-05-23 | — | — | US | claimed |
| EP-1172422-A2 | Inkjet ink sets with high lightfastness dye | Hewlett-Packard Company (US) | 2002-01-16 | — | — | EP | claimed |
| US-6063174-A | GREEN PIXELS HAVING A HIGH PERMEABILITY. | CANON KABUSHIKI KAISHA (JP) | 2000-05-16 | — | — | US | claimed |
| US-5482545-A | Ink, and ink-jet recording method and instrument using the same | CANON KABUSHIKI KAISHA (JP) | 1996-01-09 | — | — | US | claimed |
| EP-0662499-A2 | Ink, and ink-jet recording method and instrument using the same | CANON KABUSHIKI KAISHA (JP) | 1995-07-12 | — | — | EP | claimed |
| US-4880788-A | Method for preventing and treating thrombosis | BAYLOR COLLEGE OF MEDICINE (US) | 1989-11-14 | — | — | US | claimed |
| WO-1989004166-A1 | METHOD FOR PREVENTING AND TREATING OF THROMBOSIS | BMRT, LTD. (US) | 1989-05-18 | — | — | WO | claimed |