Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.47 |
| ▸ | ATIC | P31939 | 1/20 | 0.53 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.53 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GLB1 | P16278 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723334 | 1.00 | ATIC (0.53) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL445718 | 1.00 | ATIC (0.53) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL29637797 | 0.88 | SENP2 (0.69) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11345068 | 0.88 | SENP2 (0.69) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL13330173 | 0.85 | SENP2 (0.64) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL30034854 | 0.82 | SENP7 (0.46) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11751115 | 0.81 | ATIC (0.75) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL29371618 | 0.80 | CARM1 (0.47) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL4172944 | 0.80 | CARM1 (0.47) | ATICSUMO2SUMO1SENP7SENP2 | |
| SCHEMBL1618524 | 0.79 | ATIC (0.45) | ATICSUMO2SUMO1SENP7SENP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-03-17 | — | — | US | disclosed |
| US-20180303977-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-10-25 | — | — | US | disclosed |
| US-7713472-B2 | Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-05-11 | — | — | US | disclosed |
| US-7651661-B2 | Medical devices with broad spectrum antimicrobial activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-01-26 | — | — | US | disclosed |
| US-20080183152-A1 | MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY | RAAD ISSAM | 2008-07-31 | — | — | US | disclosed |
| US-20070154621-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2007-07-05 | — | — | US | disclosed |
| US-20050197634-A1 | Methods for coating and impregnating medical devices with antiseptic compositions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2005-09-08 | — | — | US | disclosed |
| EP-1010094-A4 | COMPOUND SCREENING SYSTEM | COMMW SCIENT IND RES ORG (AU) | 2001-03-07 | — | — | EP | disclosed |
| EP-1010094-A1 | COMPOUND SCREENING SYSTEM | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999012118-A1 | COMPOUND SCREENING SYSTEM | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | CUTA, CD63, CDC37 | THRB 4713/4885ATIC 4475/4885SUMO2 3065/4885 |
| US-20180303977-A1 | METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS | CUTA, CD63, CDC37 | THRB 4713/4885ATIC 4475/4885SUMO2 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.