Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768750 | 0.79 | MGLL (0.39) | MGLLALDH1A1MAPTHSD17B10 | |
| SCHEMBL4872049 | 0.77 | ALDH1A1 (0.53) | MGLLALDH1A1MAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL29995407 | 0.76 | ALDH1A1 (0.52) | MGLLALDH1A1MAPTHSD17B10 | |
| SCHEMBL24947724 | 0.75 | MAOA (0.50) | ALDH1A1 | |
| SCHEMBL2058891 | 0.75 | ALDH1A1 (0.50) | MGLLALDH1A1MAPTHSD17B10 | |
| SCHEMBL19903237 | 0.74 | HPGD (0.38) | MGLLALDH1A1MAPTHSD17B10 | |
| SCHEMBL24894074 | 0.74 | KMT2A (0.38) | MGLLALDH1A1MAPTHSD17B10 | |
| SCHEMBL24124260 | 0.74 | ALDH1A1 (0.47) | MGLLALDH1A1MAPTHSD17B10 | |
| SCHEMBL19903214 | 0.71 | HPGD (0.39) | ALDH1A1 | |
| SCHEMBL15721254 | 0.71 | MAPK1 (0.44) | ALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858910-B2 | Pyridinylmethylenepiperidine derivatives and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2024-01-02 | — | — | US | disclosed |
| US-11253596-B2 | Phenylalkylcarboxylic acid delivery agents | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2022-02-22 | — | — | US | disclosed |
| EP-3841096-A1 | PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| US-20210188803-A1 | PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-06-24 | — | — | US | disclosed |
| US-20200405863-A1 | PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS | NOVO NORDISK A/S (DK) | 2020-12-31 | — | — | US | disclosed |
| US-RE48164-E1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES INC. (US) | 2020-08-18 | — | — | US | disclosed |
| WO-2020038435-A1 | PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-02-27 | — | — | WO | disclosed |
| US-10456472-B2 | Phenylalkylcarboxylic acid delivery agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| EP-2057112-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2018-12-19 | — | — | EP | disclosed |
| US-20180334430-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2018-11-22 | — | — | US | disclosed |
| US-7608629-B2 | (Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 2009-10-27 | — | — | US | disclosed |
| US-20090258817-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | NOVO NORDISK A/S (DK) | 2009-10-15 | — | — | US | disclosed |
| US-20090220451-A1 | CYCLOPROPYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090092580-A1 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-20080269108-A1 | Crystalline forms of the Di-Sodium Salt of N-(5-Chlorosalicyloyl)-8-Aminocaprylic Acid | EMISPHERE TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20060211734-A1 | (Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-ht1f agonists | ELILILLY AND COMPANY (US) | 2006-09-21 | — | — | US | disclosed |
| US-20060211734-A1 | (Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-ht1f agonists | ELILILLY AND COMPANY (US) | 2006-09-21 | — | — | US | disclosed |
| CN-1777584-A | As 5-HT1F(Piperidyloxy) phenyl, (peridyloxy) pyridyl, (peridylthio) phenyl and (peridylthio) pyridyl compounds of agonists | LILLY CO ELI (US) | 2006-05-24 | — | — | CN | disclosed |
| EP-1626958-A1 | (PIPERIDINYLOXY)PHENYL, (PIPERIDINYLOXY)PYRIDINYL, (PIPERIDINYLSULFANYL)PHENYL AND (PIPERIDINYLSULFANYL)PYRIDINYL COMPOUNDS AS 5-HT 1F AGONISTS | ELI LILLY AND COMPANY (US) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004094380-A1 | (PIPERIDINYLOXY)PHENYL, (PIPERIDINYLOXY)PYRIDINYL, (PIPERIDINYLSULFANYL)PHENYL AND (PIPERIDINYLSULFANYL)PYRIDINYL COMPOUNDS AS 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200405863-A1 | PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS | PGF, LIPA, PDGFA | MGLL 320/4885ALDH1A1 599/4885MAPT 3128/4885 |
| US-20060211734-A1 | (Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-ht1f agonists | HTR1A, HTR1F, HTR5A | MGLL 1951/4885ALDH1A1 1062/4885MAPT 3174/4885 |
| US-11858910-B2 | Pyridinylmethylenepiperidine derivatives and uses thereof | HTR1F, HTR1A, HTR5A | MGLL 1720/4885ALDH1A1 2534/4885MAPT 2350/4885 |
| US-20090220451-A1 | CYCLOPROPYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | PAICS, ABCB4, ABCB11 | MGLL 1345/4885ALDH1A1 2599/4885MAPT 1418/4885 |
| US-20090092580-A1 | DIALKYL ETHER DELIVERY AGENTS | LIPA, SLC10A1, ABCB11 | MGLL 6/4885ALDH1A1 1567/4885MAPT 2636/4885 |
| US-20090258817-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | ABCB7, ABCB4, PAICS | MGLL 923/4885ALDH1A1 1627/4885MAPT 3043/4885 |
| US-10456472-B2 | Phenylalkylcarboxylic acid delivery agents | PGF, LIPA, PDGFA | MGLL 320/4885ALDH1A1 599/4885MAPT 3128/4885 |
| US-20180334430-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | ABCB7, ABCB4, PAICS | MGLL 923/4885ALDH1A1 1627/4885MAPT 3043/4885 |
| US-11253596-B2 | Phenylalkylcarboxylic acid delivery agents | PGF, LIPA, PDGFA | MGLL 320/4885ALDH1A1 599/4885MAPT 3128/4885 |
| US-20210188803-A1 | PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | HTR1F, HTR1A, HTR5A | MGLL 1720/4885ALDH1A1 2534/4885MAPT 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.