Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494579 | 0.80 | ALDH1A1 (0.43) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4504869 | 0.78 | ALDH1A1 (0.42) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4485204 | 0.78 | ALDH1A1 (0.42) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4485664 | 0.77 | KDM4E (0.40) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4488093 | 0.76 | VDR (0.40) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4559832 | 0.75 | TP53 (0.46) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL4492331 | 0.75 | LMNA (0.42) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4490040 | 0.73 | GFER (0.47) | SMN1; SMN2GAAALDH1A1MAPT | |
| SCHEMBL4482567 | 0.73 | PLA2G2A (0.43) | KMT2AALDH1A1 | |
| SCHEMBL4490747 | 0.73 | PGR (0.43) | MEN1KMT2ASMN1; SMN2GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |