Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609237 | 0.84 | LTA4H (0.44) | MAOAMAOBLTA4HALDH1A1MEN1 | |
| SCHEMBL9242729 | 0.84 | MAOA (0.74) | MAOAMAOBLTA4HALDH1A1KDM4E | |
| SCHEMBL457634 | 0.84 | MAOA (0.74) | MAOAMAOBLTA4HALDH1A1KDM4E | |
| SCHEMBL919860 | 0.81 | MAOA (0.37) | MAOAMAOBLTA4HALDH1A1KDM4E | |
| SCHEMBL30385926 | 0.81 | MAOA (0.70) | MAOAMAOBLTA4HALDH1A1KDM4E | |
| SCHEMBL8748154 | 0.79 | ALDH3A1 (0.49) | MAOAMAOBLTA4HSMN1; SMN2KCNH2 | |
| SCHEMBL10839908 | 0.79 | ALDH1A1 (0.39) | MAOALTA4HALDH1A1MEN1MAPT | |
| SCHEMBL693602 | 0.78 | HSP90AA1 (0.55) | MEN1KMT2AHAO1HTR2ASLC6A4 | |
| SCHEMBL921574 | 0.78 | SOS1 (0.57) | MAPTSMN1; SMN2ARHTR2ASLC6A4 | |
| SCHEMBL8535186 | 0.77 | LTA4H (0.63) | MAOAMAOBLTA4HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344265-A | Amide compound and preparation method and application thereof | 河北大学 | 2024-07-16 | — | — | CN | claimed |
| WO-2022012550-A1 | SUBSTITUTED 1H-IMIDAZO [1, 2-B] PYRAZOLE-3-CARBOXAMIDE AS BRUTON'S TYROSINE KINASE INHIBITORS | HENAN NORMAL UNIVERSITY (CN) | 2022-01-20 | — | — | WO | claimed |
| US-10435376-B2 | Derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs | Guangzhou Insighter Biotechnology Co., Ltd. (CN) | 2019-10-08 | — | — | US | claimed |
| US-20180370921-A1 | Derivatives of 1H-imidazole-4,5-dicarboxamide and Use Thereof in Preparation of Anticoccidial Drugs | GUANGZHOU INSIGHTER BIOTECHNOLOGY CO.,LTD. (CN) | 2018-12-27 | — | — | US | claimed |
| CN-104672145-A | Glycalpyramide derivative and application thereof in preparing anticoccidial drug | GUANGZHOU INSIGHTER BIOTECHNOLOGY CO LTD | 2015-06-03 | — | — | CN | claimed |
| CN-102459166-B | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2015-03-25 | — | — | CN | claimed |
| US-8962607-B2 | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2015-02-24 | — | — | US | claimed |
| EP-2421823-B1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-01-14 | — | — | EP | claimed |
| US-20140243305-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (US) | 2014-08-28 | — | — | US | claimed |
| US-20130210769-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2013-08-15 | — | — | US | claimed |
| EP-0556377-A1 | NEMATICIDAL USE OF 4-ARALKYLPYRIDINES | DOWELANCO (US) | 1993-08-25 | — | — | EP | claimed |
| WO-1993004579-A1 | NEMATICIDAL USE OF 4-ARALKYLPYRIDINES | DOWELANCO (US) | 1993-03-18 | — | — | WO | claimed |
| US-4769493-A | Process for producing tetrafluorophthalic acid | SDS BIOTECH K.K. (JP) | 1988-09-06 | — | — | US | claimed |
| EP-0165775-A1 | Antifungal azole compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-12-27 | — | — | EP | claimed |
| EP-0115473-A2 | Substituted pyrrolidinone derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1984-08-08 | — | — | EP | claimed |
| US-4317673-A | MIXTURE OF /-TRIFLUOROPHENYL; 3-CHLORO, 4-CHLOROMETHYL-2-PYRROLIDONE AND AN N-P-CHLOROPHENOXYPHENYL-N*,N*-DIALKYL UREA | STAUFFER CHEMICAL COMPANY (US) | 1982-03-02 | — | — | US | claimed |
| US-4262851-A | HIGH SPEED MILLING WITHOUT SURFACTANTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-21 | — | — | US | claimed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | claimed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | claimed |
| US-3959332-A | N-(2-NITRO-4-ARYLOXYSULFONYL-PHENYL)-ARYLENEDIAMINES, DYES | SANDOZ LTD. (CH) | 1976-05-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180370921-A1 | Derivatives of 1H-imidazole-4,5-dicarboxamide and Use Thereof in Preparation of Anticoccidial Drugs | CYP3A5, DDC, CPS1 | MAOA 1483/4885MAOB 2024/4885LTA4H 1794/4885 |
| US-20140243305-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | PNLIP, LPL, LIPA | MAOA 467/4885MAOB 428/4885LTA4H 108/4885 |
| US-10435376-B2 | Derivatives of 1H-imidazole-4,5-dicarboxamide and use thereof in preparation of anticoccidial drugs | CYP3A5, DDC, CPS1 | MAOA 1483/4885MAOB 2024/4885LTA4H 1794/4885 |
| US-20130210769-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | CNR1, CNR2, FAAH | MAOA 1534/4885MAOB 1474/4885LTA4H 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.