Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2849841 | 0.98 | APP (0.40) | APPLMNAALDH1A1MAPK1SLC22A2 | |
| Hydrochloric Acid SCHEMBL3861963 | 0.98 | APP (0.40) | APPLMNAALDH1A1MAPK1SLC22A2 | |
| SCHEMBL13050090 | 0.92 | LMNA (0.40) | APPLMNAALDH1A1MAPK1SLC22A2 | |
| SCHEMBL9643514 | 0.91 | ALDH1A1 (0.41) | APPLMNAALDH1A1MAPK1BLM | |
| SCHEMBL3857753 | 0.88 | PRSS1 (0.42) | APPLMNAALDH1A1MAPK1ACHE | |
| SCHEMBL484008 | 0.81 | TDP1 (0.40) | APPLMNAALDH1A1MAPK1TSHR | |
| SCHEMBL33766 | 0.80 | APP (0.48) | APPLMNAALDH1A1CYP2C19MAPT | |
| SCHEMBL4006637 | 0.79 | ALDH1A1 (0.54) | APPLMNAALDH1A1MAPK1SLC22A2 | |
| SCHEMBL14596281 | 0.79 | TSHR (0.50) | APPLMNAALDH1A1MAPK1SLC22A2 | |
| Hydrochloric Acid SCHEMBL21056194 | 0.78 | APP (0.47) | APPLMNAALDH1A1MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 450 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12383482-B2 | Hair coloring compositions | WELLA GERMANY GMBH (DE) | 2025-08-12 | — | — | US | claimed |
| EP-4251285-B1 | HAIR COLORING COMPOSITIONS | WELLA INT OPERATIONS SWITZERLAND SARL (CH) | 2024-09-04 | — | — | EP | claimed |
| US-20240024218-A1 | HAIR COLORING COMPOSITIONS | WELLA GERMANY GMBH (DE) | 2024-01-25 | — | — | US | claimed |
| EP-4251285-A1 | HAIR COLORING COMPOSITIONS | Wella International Operations Switzerland Sàrl (CH) | 2023-10-04 | — | — | EP | claimed |
| WO-2022112473-A1 | HAIR COLORING COMPOSITIONS | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2022-06-02 | — | — | WO | claimed |
| EP-3263180-B1 | METHOD FOR COLORING HAIR FIBERS INTO A FIRST AND A SECOND PATTERNS | NOXELL CORP (US) | 2020-04-08 | — | — | EP | claimed |
| US-20190269945-A1 | METHOD FOR COLORING HAIR FIBERS INTO A FIRST AND A SECOND PATTERNS | NOXELL CORP (US) | 2019-09-05 | — | — | US | claimed |
| EP-3281623-B1 | HAIR COLORING COMPOSITION FOR PROVIDING A FILM ON KERATIN FIBERS | NOXELL CORP (US) | 2019-07-31 | — | — | EP | claimed |
| US-20190201308-A1 | METHOD FOR COLORING HAIR | NOXELL CORPORATION | 2019-07-04 | — | — | US | claimed |
| US-20190160000-A1 | HAIR COLORING COMPOSITION FOR PROVIDING A FILM ON KERATIN FIBERS | WELLA OPERATIONS US, LLC | 2019-05-30 | — | — | US | claimed |
| WO-2013058817-A1 | OXIDATIVE DYEING COMPOSITIONS COMPRISING AN 1-HEXYL/HEPTYL-4,5-DIAMINOPYRAZOLE AND A M-AMINOPHENOL AND DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2013-04-25 | — | — | WO | claimed |
| US-20120210521-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Benzo[1,3]dioxol-5-ylamine and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | claimed |
| US-20120210524-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Benzene-1,3-diamine and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | claimed |
| US-20120210519-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a 2-Aminophenol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | claimed |
| US-20120210522-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Naphthalen-1-ol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | claimed |
| US-20120210525-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexy1/Hepty1-4,5-diaminopyrazole and a Benzene-1,3-diol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | claimed |
| US-20120210520-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a m-Aminophenol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | claimed |
| US-20120210526-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Pyridine and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | claimed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | claimed |
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120210521-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Benzo[1,3]dioxol-5-ylamine and Derivatives Thereof | KRT18, HK1, AOX1 | APP 3441/4885LMNA 672/4885ALDH1A1 161/4885 |
| US-20120210520-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a m-Aminophenol and Derivatives Thereof | KRT18, AOC1, S100P | APP 2261/4885LMNA 1550/4885ALDH1A1 153/4885 |
| US-20120210526-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Pyridine and Derivatives Thereof | KRT18, NOX4, AOC1 | APP 2561/4885LMNA 1684/4885ALDH1A1 169/4885 |
| US-20190201308-A1 | METHOD FOR COLORING HAIR | TYR, CYB5R3, ALDH1A3 | APP 1903/4885LMNA 1342/4885ALDH1A1 41/4885 |
| US-20120210525-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexy1/Hepty1-4,5-diaminopyrazole and a Benzene-1,3-diol and Derivatives Thereof | AOC1, AOX1, HK1 | APP 2245/4885LMNA 4062/4885ALDH1A1 26/4885 |
| US-20120210519-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a 2-Aminophenol and Derivatives Thereof | TYR, GPX4, TH | APP 2735/4885LMNA 3787/4885ALDH1A1 18/4885 |
| US-20120210522-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Naphthalen-1-ol and Derivatives Thereof | AOC1, NOX1, AOX1 | APP 1910/4885LMNA 2627/4885ALDH1A1 55/4885 |
| US-20120210524-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Benzene-1,3-diamine and Derivatives Thereof | KRT18, AOC1, NOX4 | APP 2598/4885LMNA 1684/4885ALDH1A1 55/4885 |
| US-20190269945-A1 | METHOD FOR COLORING HAIR FIBERS INTO A FIRST AND A SECOND PATTERNS | COXFA4L2, KRT18, SHH | APP 2799/4885LMNA 854/4885ALDH1A1 378/4885 |
| US-20190160000-A1 | HAIR COLORING COMPOSITION FOR PROVIDING A FILM ON KERATIN FIBERS | KRT18, CUTA, POTEE | APP 1233/4885LMNA 301/4885ALDH1A1 1285/4885 |
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | KRT18, CDC73, DSP | APP 676/4885LMNA 214/4885ALDH1A1 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.