Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614158 | 0.80 | NPC1 (0.42) | RAB9ANPC1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL4616052 | 0.79 | ALDH1A1 (0.43) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4616109 | 0.77 | MAPT (0.42) | ARRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL4616110 | 0.77 | MAPT (0.42) | ARRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL5289255 | 0.74 | HSD17B1 (0.44) | CYP2C9CYP2C19 | |
| SCHEMBL4616837 | 0.74 | ALDH1A1 (0.45) | ARALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL5708545 | 0.74 | NPC1 (0.38) | ARRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL4616586 | 0.73 | ADORA3 (0.48) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5708532 | 0.73 | NPC1 (0.45) | ARRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL5288475 | 0.73 | MAOA (0.41) | ARRAB9ANPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601335-B1 | MEANS AND METHOD FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES | WELLA AG (DE) | 2008-03-19 | — | — | EP | claimed |
| US-7326254-B2 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | WELLA AG (DE) | 2008-02-05 | — | — | US | claimed |
| US-7291183-B2 | Agent and method for dyeing keratin fibers | WELLA AG (DE) | 2007-11-06 | — | — | US | claimed |
| EP-1599179-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | claimed |
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2006-07-27 | — | — | US | claimed |
| US-20060010616-A1 | Agent and method for dyeing keratin fibers | Wella GmbH (DE) | 2006-01-19 | — | — | US | claimed |
| US-7429274-B2 | Agent and method for the oxidative coloring of keratin fibers | WELLA AG (DE) | 2008-09-30 | — | — | US | disclosed |
| US-7326254-B2 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | WELLA AG (DE) | 2008-02-05 | — | — | US | disclosed |
| US-7291183-B2 | Agent and method for dyeing keratin fibers | WELLA AG (DE) | 2007-11-06 | — | — | US | disclosed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | Wella GmbH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | disclosed |
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | disclosed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | disclosed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | disclosed |
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2006-07-27 | — | — | US | disclosed |
| US-20060010616-A1 | Agent and method for dyeing keratin fibers | Wella GmbH (DE) | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | KRT18, GPX4, NOX4 | GSTP1 1617/4885AR 4238/4885RAB9A 3286/4885 |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | KRT18, KIT, AOC1 | GSTP1 1941/4885AR 2030/4885RAB9A 3292/4885 |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | KRT18, CDC73, OAT | GSTP1 1474/4885AR 855/4885RAB9A 2841/4885 |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | KRT18, KIT, CKMT1A; CKMT1B | GSTP1 867/4885AR 2888/4885RAB9A 2070/4885 |
| US-20060010616-A1 | Agent and method for dyeing keratin fibers | KRT18, KIT, MKI67 | GSTP1 1687/4885AR 2342/4885RAB9A 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.