Acrylic Acid

Acrylic Acid

SCHEMBL4647102

C=CC(=O)[O-].C=CC(=O)[O-].[H+].[Na+]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA4 known ✓ P22748 3/20 0.40
CA1 known ✓ P00915 2/20 0.38
LMNA P02545 2/20 0.44
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
FGFR4 P22455 1/20 0.41
FAHD1 Q6P587 1/20 0.40
MEN1 O00255 1/20 0.33
LDHA P00338 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL16257 0.96
Acrylic Acid SCHEMBL1082680 0.96 LMNA (0.47) LMNAALDH1A1TSHRFGFR4CA4
Acrylic Acid SCHEMBL988622 0.96
Acrylic Acid SCHEMBL11033079 0.92
Acrylic Acid SCHEMBL21246905 0.92 LMNA (0.44) LMNAALDH1A1TSHRFGFR4CA4
Acrylic Acid SCHEMBL9418472 0.92
Acrylic Acid SCHEMBL10632946 0.92 CA4 (0.50) LMNAALDH1A1TSHRFGFR4CA4
Acrylic Acid SCHEMBL21246904 0.92
Acrylic Acid SCHEMBL1367649 0.92
Acrylic Acid SCHEMBL16447654 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9931679-B2 Method for cleaning hard surfaces KIMBERLY-CLARK WORLDWIDE, INC. (US) 2018-04-03 US disclosed
US-20160325318-A1 METHOD FOR CLEANING HARD SURFACES KIMBERLY CLARK CO (US) 2016-11-10 US disclosed
US-9272281-B2 Method and device for targeted process control in a microfluidic processor having integrated active elements Technische Universität Dresden (DE) 2016-03-01 US disclosed
WO-2015103380-A1 METHOD FOR CLEANING HARD SURFACES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2015-07-09 WO disclosed
US-20150181863-A1 FLEXIBLE SUPERABSORBENT BINDER POLYMER AND ANTIMICROBIAL AGENT COMPOSITION EVONIK INDUSTRIES AG (DE) 2015-07-02 US disclosed
US-20150044688-A1 Method and Device for Targeted Process Control in a Microfluidic Processor Having Integrated Active Elements Technische Universität Dresden (DE) 2015-02-12 US disclosed
EP-1966257-B1 FLEXIBLE SUPERABSORBENT BINDER POLYMER COMPOSITION EVONIK CORP (US) 2014-09-10 EP disclosed
EP-1957122-B1 ARTICLES COMPRISING FLEXIBLE SUPERABSORBENT BINDER POLYMER COMPOSITION KIMBERLY CLARK CO (US) 2013-01-02 EP disclosed
CN-101356202-B Flexible superabsorbent binder polymer composition STOCKHAUSEN INC 2011-05-25 CN disclosed
CN-101356202-A Flexible superabsorbent binder polymer composition STOCKHAUSEN INC (US) 2009-01-28 CN disclosed
EP-1957122-A2 ARTICLES COMPRISING FLEXIBLE SUPERABSORBENT BINDER POLYMER COMPOSITION Kimberly-Clark Worldwide, Inc. (US) 2008-08-20 EP disclosed
US-7399813-B2 Flexible superabsorbent binder polymer composition STOCKHAUSSEN, INC. (US) 2008-07-15 US disclosed
US-7335713-B2 Method for preparing a flexible superabsorbent binder polymer composition STOCKHAUSEN, INC. (US) 2008-02-26 US disclosed
US-7312286-B2 Flexible superabsorbent binder polymer composition STOCKHAUSEN, INC. (US) 2007-12-25 US disclosed
US-20070265405-A1 FLEXIBLE SUPERABSORBENT BINDER POLYMER COMPOSITION STOCKHAUSEN, INC. 2007-11-15 US disclosed
WO-2007111716-A2 FLEXIBLE SUPERABSORBENT BINDER POLYMER COMPOSITION EVONIK STOCKHAUSEN, INC. (US) 2007-10-04 WO disclosed
WO-2007067277-A2 ARTICLES COMPRISING FLEXIBLE SUPERABSORBENT BINDER POLYMER COMPOSITION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2007-06-14 WO disclosed
US-20070129697-A1 Articles comprising flexible superabsorbent binder polymer composition KIMBERLY-CLARK WORLDWIDE, INC. 2007-06-07 US disclosed
US-20070129517-A1 METHOD FOR PREPARING A FLEXIBLE SUPERABSORBENT BINDER POLYMER COMPOSITION EVONIK SUPERABSORBER LLC 2007-06-07 US disclosed
US-20070129515-A1 Flexible superabsorbent binder polymer composition EVONIK CORPORATION 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150181863-A1 FLEXIBLE SUPERABSORBENT BINDER POLYMER AND ANTIMICROBIAL AGENT COMPOSITION FLOT1, PCNA, SI CA4 2167/4885CA1 2978/4885LMNA 4394/4885
US-20160325318-A1 METHOD FOR CLEANING HARD SURFACES SPOUT1, CD2, SIGLEC7 CA4 2941/4885CA1 2716/4885LMNA 3950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.