Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | USP1 | O94782 | 1/20 | 0.49 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966421 | 0.84 | KCNA5 (0.54) | KCNA5KCNH2MKNK1MKNK2CYP2A6 | |
| SCHEMBL10967673 | 0.84 | MKNK1 (0.55) | KCNA5KCNH2MKNK1MKNK2CYP2A6 | |
| SCHEMBL3273759 | 0.83 | KCNA5 (0.59) | KCNA5KCNH2MKNK1MKNK2CYP2A6 | |
| SCHEMBL21480329 | 0.83 | KCNA5 (0.59) | KCNA5KCNH2MKNK1MKNK2CYP2A6 | |
| SCHEMBL1130345 | 0.83 | KCNA5 (0.59) | KCNA5KCNH2MKNK1MKNK2CYP2A6 | |
| SCHEMBL3288789 | 0.83 | DPP4 (0.62) | KCNA5KCNH2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL9285273 | 0.83 | KCNA5 (0.59) | KCNA5KCNH2CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL27703205 | 0.82 | ATM (0.45) | KCNA5KCNH2CYP2A6CYP11B1USP1 | |
| SCHEMBL30091380 | 0.82 | PDCD1 (0.69) | KCNA5KCNH2MKNK1MKNK2CYP2A6 | |
| SCHEMBL11074941 | 0.82 | PDCD1 (0.69) | KCNA5KCNH2MKNK1MKNK2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894896-A | Inhibitors of green peroxidase | 阿斯利康(瑞典)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-115413657-B | Application of cinnamic acid derivative in mosquito control | 深圳市纬信科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| US-20240166642-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-05-23 | — | — | US | disclosed |
| CN-113354832-B | Cation Ag (I) -organic framework material and preparation method and application thereof | 天津农学院 | 2023-01-10 | — | — | CN | disclosed |
| CN-115413657-A | Application of cinnamic acid derivative in mosquito control | 五邑大学 | 2022-12-02 | — | — | CN | disclosed |
| CN-113354832-A | Cation Ag (I) -organic framework material and preparation method and application thereof | 天津农学院 | 2021-09-07 | — | — | CN | disclosed |
| US-8563786-B2 | Method for producing optically active alcohol | MITSUI CHEMICALS, INC. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-8546374-B2 | Amino-tetrazoles analogues and methods of use | ABBVIE INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120329772-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2012-12-27 | — | — | US | disclosed |
| US-8217067-B2 | Antiinflammatory agents, antidepressants, analgesics, purinergic receptor antagonists; neurodegenerative diseases, spinal cord injuries; 1-(2,3-dichlorophenyl)-N-[(2-methylphenyl)methyl]-1H-tetraazol-5-amine | ABBOTT LABORATORIES (US) | 2012-07-10 | — | — | US | disclosed |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-04-12 | — | — | US | disclosed |
| EP-2412694-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | Mitsui Chemicals, Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-7723367-B2 | Amino-tetrazoles analogues and methods of use | ABBOTT LABORATORIES (US) | 2010-05-25 | — | — | US | disclosed |
| US-7704997-B1 | Amino-tetrazole analogues and methods of use | ABBOTT LABORATORIES (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080171733-A1 | Amino-Tetrazoles Analogues and Methods of Use | ABBOTT LABORATORIES (US) | 2008-07-17 | — | — | US | disclosed |
| US-20070049584-A1 | Amino-tetrazoles analogues and methods of use | ABBVIE INC. | 2007-03-01 | — | — | US | disclosed |
| US-20060052374-A1 | Amino-tetrazole analogues and methods of use | ABBVIE INC. | 2006-03-09 | — | — | US | disclosed |
| EP-0148826-A1 | FUNGICIDAL, HERBICIDAL AND PLANT GROWTH REGULATING PYRIDYL-CONTAINING ETHERS | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1985-07-24 | — | — | EP | disclosed |
| WO-1985000289-A1 | FUNGICIDAL, HERBICIDAL AND PLANT GROWTH REGULATING PYRIDYL-CONTAINING ETHERS | CHEVRON RESEARCH COMPANY (US) | 1985-01-31 | — | — | WO | disclosed |
| US-4407806-A | PRE- AND POSTEMERGENCE HERBICIDES | CHEVRON RESEARCH COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171733-A1 | Amino-Tetrazoles Analogues and Methods of Use | P2RX7, P2RX2, P2RX5 | KCNA5 116/4885KCNH2 333/4885MKNK1 3927/4885 |
| US-20120329772-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | P2RX7, P2RX2, P2RX5 | KCNA5 116/4885KCNH2 333/4885MKNK1 3927/4885 |
| US-20240166642-A1 | INHIBITORS OF MYELOPEROXIDASE | MPO, XDH, EPX | KCNA5 2037/4885KCNH2 2795/4885MKNK1 4399/4885 |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | ADH1A, ADH1C, FHIT | KCNA5 795/4885KCNH2 710/4885MKNK1 2137/4885 |
| US-20070049584-A1 | Amino-tetrazoles analogues and methods of use | P2RX7, P2RX2, P2RX5 | KCNA5 116/4885KCNH2 333/4885MKNK1 3927/4885 |
| US-20060052374-A1 | Amino-tetrazole analogues and methods of use | P2RX7, P2RX2, P2RX3 | KCNA5 96/4885KCNH2 281/4885MKNK1 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.